Wrist and Forearm Amputations Workup
- Author: Scott G Edwards, MD; Chief Editor: Harris Gellman, MD more...
Laboratory Studies
- Hematocrit and hemoglobin levels should be monitored. In trauma situations, acute blood loss is a concern. Even with elective amputations, postoperative bleeding and hematoma formation require careful assessment. Acceptable levels are individualized based on age, associated medical problems and injuries, and baseline values. In general, a young, otherwise healthy patient should maintain a hematocrit/hemoglobin level greater than 20/6. Elderly patients or patients with underlying cardiovascular disease should be maintained at higher levels (30/10).
- Creatinine levels should be monitored. In individuals with muscle injury and necrosis, myoglobin enters the systemic circulation and can lead to renal insufficiency and failure. This is especially true in individuals with thermal and electrical burns. If creatinine levels continue to rise more than 0.4 over baseline, preoperative, or preinjury levels, more aggressive surgical intervention and fluid hydration should be considered.
- Potassium and calcium levels should be monitored. As dead tissue is metabolized, destroyed cells release intracellular stores of potassium and calcium into the extracellular space. Elevated levels of these electrolytes may lead to cardiac arrhythmias and seizures.
- White blood cell count, C-reactive protein, and erythrocyte sedimentation rate values should be monitored in persons with infection. Observe that these values normalize following amputation, thus suggesting resolution of the infection. Expect the C-reactive protein to be the first laboratory value to respond to treatment, as the 2 others may take several days to weeks to normalize despite eradication of the infection. If these values remain elevated or rise further, treatment should be reassessed by considering changing to a more appropriate antibiotic, searching for an unrelated occult infection or hidden abscess, and possibly revising the amputation at a more proximal level.
- Platelets should be monitored periodically if subcutaneous heparin is administered postoperatively. Heparin-induced thrombocytopenia may occur even in small subcutaneous doses.
Imaging Studies
- With few exceptions, plain radiographs should be included in preoperative planning. The presence of hardware or occult pathology in an extremity to be amputated is an embarrassing intraoperative discovery.
- In oncology cases, a preoperative CT scan and MRI have proven invaluable in assessing the extent of tumor involvement and level of amputation. Occasionally, a preoperative CT scan or MRI is helpful to evaluate the extent of infection and abscess in these particular settings.
- Magnetic resonance angiography remains a noninvasive alternative to arteriography. The complications of arterial puncture are avoided, the risk of contrast-related renal failure is eliminated, and sensitivity is higher than in contrast angiography in the identification of severe peripheral arterial occlusive disease. Because of the expense and expertise involved, many medical centers cannot offer this alternative.
- Pyrophosphate nuclear scanning has been introduced as another noninvasive method of evaluating tissue viability.[10] It has been demonstrated to be a useful adjunct in predicting the need for amputation in persons with extremities damaged by electrical injury, frostbite, or invasive infection. Pyrophosphate nuclear scanning has a sensitivity of 94%, a specificity of 100%, and an accuracy rate of 96%.
Other Tests
- Doppler ultrasound detects blood flow, and, when used in conjunction with blood pressure cuffs, can measure arterial pressure at different levels in the upper extremity.
- Transcutaneous oxygen tensions reflect tissue perfusion. Significant occlusive disease causes these measurements to fall below 35 mm Hg. When considering the level of amputation, it is imperative that transcutaneous oxygen tensions at the level of incision are at least 35 mm Hg because measurements below this are associated with decreased healing and wound problems. Measurement of tissue oxygen tension is not affected by incompressible calcified vessels and appears to be very sensitive in evaluating arterial occlusive disease during exercise.
Diagnostic Procedures
- Arteriography remains the criterion standard for the definitive analysis of vascular status. However, because this is an invasive procedure, arteriography carries increased risks for pseudoaneurysm, hematoma, and vascular embolism.
Louis DS, Jebson PJL, Graham TJ. Amputations. In: Green DP, Hotchkiss RN, Pederson WC, eds. Green's Operative Hand Surgery. 4th ed. New York, NY: Churchill Livingstone; 1999:48-94.
Tooms RE. General Principles of Amputations. In: Canale ST, ed. Campbell's Operative Orthopaedics. 9th ed. St. Louis, Mo: CV Mosby; 1998:521-531.
Tooms RE. Amputations of Upper Extremity. In: Canale ST, ed. Campbell's Operative Orthopaedics. 9th ed. St. Louis, Mo: CV Mosby; 1998:550-560.
Levy CE, Bryant PR, Spires MC. Acquired limb deficiencies. 4. Troubleshooting. Arch Phys Med Rehabil. Mar 2001;82(3 Suppl 1):S25-30. [Medline].
Pandian G, Huang ME, Duffy DA. Acquired limb deficiencies. 2. Perioperative management. Arch Phys Med Rehabil. Mar 2001;82(3 Suppl 1):S9-S16. [Medline].
Atroshi I, Rosberg HE. Epidemiology of amputations and severe injuries of the hand. Hand Clin. Aug 2001;17(3):343-50, vii. [Medline].
Lutz BS, Klauke T, Dietrich FE. Late results after microvascular reconstruction of severe crush and avulsion injuries of the upper extremity. J Reconstr Microsurg. Aug 1997;13(6):423-9. [Medline].
DeBono R. A histological analysis of a high voltage electric current injury to an upper limb. Burns. Sep 1999;25(6):541-7. [Medline].
Hoppenfield S, deBoer P. The forearm. In: Surgical Exposures in Orthopaedics: The Anatomic Approach. 2nd ed. Philadelphia, Pa: JB Lippincott; 1994:117-146.
Affleck DG, Edelman L, Morris SE. Assessment of tissue viability in complex extremity injuries: utility of the pyrophosphate nuclear scan. J Trauma. Feb 2001;50(2):263-9. [Medline].
Louis DS, Hunter LY, Keating TM. Painful neuromas in long below-elbow amputees. Arch Surg. Jun 1980;115(6):742-4. [Medline].
Martini A, Fromm B. A new operation for the prevention and treatment of amputation neuromas. J Bone Joint Surg Br. May 1989;71(3):379-82. [Medline].
Jones ML, Blair WF. Salvage of a below-elbow amputation stump with a free latissimus dorsi muscle flap: a case report. J Hand Surg [Am]. Mar 1994;19(2):207-8.
Swanson AB, Swanson GD. The Krukenberg procedure in the juvenile amputee. Clin Orthop. May 1980;(148):55-61. [Medline].
Nathan PA, Trung NB. The Krukenberg operation: a modified technique avoiding skin grafts. J Hand Surg [Am]. Mar 1977;2(2):127-30. [Medline].
Garst RJ. The Krukenberg hand. J Bone Joint Surg Br. May 1991;73(3):385-8. [Medline].
Malone JM, Fleming LL, Roberson J. Immediate, early, and late postsurgical management of upper-limb amputation. J Rehabil Res Dev. May 1984;21(1):33-41. [Medline].
Grunert BK, Hargarten SW, Matloub HS. Predictive value of psychological screening in acute hand injuries. J Hand Surg [Am]. Mar 1992;17(2):196-9. [Medline].
Dettmers C, Adler T, Rzanny R, et al. Increased excitability in the primary motor cortex and supplementary motor area in patients with phantom limb pain after upper limb amputation. Neurosci Lett. Jul 13 2001;307(2):109-12. [Medline].
Karl A, Birbaumer N, Lutzenberger W. Reorganization of motor and somatosensory cortex in upper extremity amputees with phantom limb pain. J Neurosci. May 15 2001;21(10):3609-18. [Medline].
Kawashima N, Mita T. Metal bar prevents phantom limb motion: case study of an amputation patient who showed a profound change in the awareness of his phantom limb. Neurocase. Dec 2009;15(6):478-84. [Medline].
Speer DP. The pathogenesis of amputation stump overgrowth. Clin Orthop. Sep 1981;(159):294-307. [Medline].
Blume P, Salonga C, Garbalosa J, Pierre-Paul D, Key J, Gahtan V, et al. Predictors for the healing of transmetatarsal amputations: retrospective study of 91 amputations. Vascular. May-Jun 2007;15(3):126-33. [Medline].
Spikowska A, Stryla W. Analysis of quality of life in persons after arm amputations. Chir Narzadow Ruchu Ortop Pol. 2000;65(6):665-73. [Medline].
Li G, Kuiken TA. EMG pattern recognition control of multifunctional prostheses by transradial amputees. Conf Proc IEEE Eng Med Biol Soc. 2009;2009:6914-7. [Medline].
Castellini C, Fiorilla AE, Sandini G. Multi-subject/daily-life activity EMG-based control of mechanical hands. J Neuroeng Rehabil. Nov 17 2009;6:41. [Medline]. [Full Text].
Jones NF, Schneeberger S. Arm transplantation: prospects and visions. Transplant Proc. Mar 2009;41(2):476-80. [Medline].

