Follow-up
Complications
- Scurvy is fatal if untreated.
Prognosis
- Patients respond quickly to oral therapy.
- Spontaneous bleeding stops within 1 day.
- Muscle and bone pain abate quickly.
- Bleeding and sore gums heal in 2-3 days.
- Ecchymoses heal within 12 days.
- In advanced scurvy, serum bilirubin normalizes in less than a week. Anemia is corrected in less than a month.
Miscellaneous
Medicolegal Pitfalls
- Failure to recognize the condition
- Failure to properly treat the condition with administration of vitamin C
More on Scurvy |
| Overview: Scurvy |
| Differential Diagnoses & Workup: Scurvy |
| Treatment & Medication: Scurvy |
Follow-up: Scurvy |
| Multimedia: Scurvy |
| References |
| Further Reading |
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References
Leger D. Scurvy: reemergence of nutritional deficiencies. Can Fam Physician. Oct 2008;54(10):1403-6. [Medline]. [Full Text].
Hampl JS, Taylor CA, Johnston CS. Vitamin C deficiency and depletion in the United States: the Third National Health and Nutrition Examination Survey, 1988 to 1994. Am J Public Health. May 2004;94(5):870-5. [Medline]. [Full Text].
Hercberg S, Preziosi P, Galan P, et al. Vitamin status of a healthy French population: dietary intakes and biochemical markers. Int J Vitam Nutr Res. 1994;64(3):220-32. [Medline].
Mosdol A, Erens B, Brunner EJ. Estimated prevalence and predictors of vitamin C deficiency within UK's low-income population. J Public Health (Oxf). Dec 2008;30(4):456-60. [Medline].
Gan R, Eintracht S, Hoffer LJ. Vitamin C deficiency in a university teaching hospital. J Am Coll Nutr. Jun 2008;27(3):428-33. [Medline].
Biesalski HK. Parenteral ascorbic acid in haemodialysis patients. Curr Opin Clin Nutr Metab Care. Nov 2008;11(6):741-6. [Medline].
Singer R, Rhodes HC, Chin G, et al. High prevalence of ascorbate deficiency in an Australian peritoneal dialysis population. Nephrology (Carlton). Feb 2008;13(1):17-22. [Medline].
Carr AC, Frei B. Toward a new recommended dietary allowance for vitamin C based on antioxidant and health effects in humans. Am J Clin Nutr. Jun 1999;69(6):1086-107. [Medline]. [Full Text].
Fain O. Musculoskeletal manifestations of scurvy. Joint Bone Spine. 2005;72:124-128. [Medline].
Fauci AS, Braunwald E, Isselbacher KJ, et al, eds. Harrison's Principles of Internal Medicine. 14th ed. New York, NY: McGraw-Hill; 1998:484-5.
Johnston CS, Thompson LL. Vitamin C status of an outpatient population. J Am Coll Nutr. Aug 1998;17(4):366-70. [Medline]. [Full Text].
Jukes TH. The prevention and conquest of scurvy, beri-beri, and pellagra. Prev Med. Nov 1989;18(6):877-83. [Medline].
Levine M, Rumsey SC, Daruwala R, et al. Criteria and recommendations for vitamin C intake. JAMA. Apr 21 1999;281(15):1415-23. [Medline].
Olmedo JM, Yiannias JA, Windgassen EB, et al. Scurvy: a disease almost forgotten. Int J Dermatol. Aug 2006;45(8):909-13. [Medline].
Pimentel L. Scurvy: historical review and current diagnostic approach. Am J Emerg Med. Jul 2003;21(4):328-32. [Medline].
Schuman RW, Rahmin M, Dannenberg AJ. Scurvy and the gastrointestinal tract. Gastrointest Endosc. Feb 1997;45(2):195-6. [Medline].
Smith MS. The diagnosis and treatment of scurvy: an historical perspective. J R Nav Med Serv. Summer 1986;72(2):104-6. [Medline].
Toole MJ. Micronutrient deficiencies in refugees. Lancet. May 16 1992;339(8803):1214-6. [Medline].
Further Reading
Related eMedicine topics:
Celiac Sprue
Celiac Disease
Crohn Disease [Gastroenterology]
Crohn Disease [Pediatrics: General Medicine]
Crohn Disease [Radiology]
Malabsorption
Malabsorption Syndromes
Malnutrition
Scurvy [Dermatology]
Scurvy [Pediatrics: General Medicine]
Scurvy [Radiology]
Sprue
Whipple Disease [Gastroenterology]
Whipple Disease [Neurology]
Clinical guidelines:
Celiac disease. National Institutes of Health (NIH) Consensus Development Panel on Celiac Disease - Independent Expert Panel
Office of Medical Applications of Research (NIH) - Federal Government Agency [U.S.]. 2004 Aug 9. 15 pages. NGC:003830
Guideline for the diagnosis and treatment of celiac disease in children: recommendations of the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition. North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition - Professional Association. 2005 Jan. 19 pages. NGC:004186
Clinical trials:
Celiac Disease Prevention
Urinary Vitamin C Loss in Diabetic Subjects
Keywords
scurvy, vitamin C, ascorbic acid, vitamin C deficiency, vitamins, vitamin, vitamin deficiency, redox, malabsorption, vitamin C foods, ascorbic acid deficiency, malabsorption syndromes
Follow-up: Scurvy