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Histology of Bone: Multimedia
Updated: Jan 28, 2008
Multimedia
 | Media file 1: Cortical bone is composed of haversian systems (osteons). Each osteon has a central haversian canal and peripheral concentric layers of lamellae. |
 | Media file 2: Growth plate. |
 | Media file 3: Trabecular bone and the surrounding hematopoietic cells, as well as adipose tissue in medullary cavity. |
 | Media file 4: Mature trabecular bone exhibits lamellae and osteocytes between the lamellae. Inactive osteocytes are also present on the bone surface with a flattened shape. |
 | Media file 5: Woven bone under a polarized microscope; collagen fibers are arranged in disorganized arrays. |
 | Media file 6: Tooth socket in adults. |
 | Media file 7: Tendon insertion site in adults. |
 | Media file 8: Osteon of mature bone viewed under a polarized microscope; lamellae are shown as alternating dark and bright layers due to the perpendicular orientation of the collagen fibers in the neighboring lamellae. |
 | Media file 9: Osteoblasts in cytologic preparation (Diff-Quik stain). Each active osteoblast has eccentrically located nuclei with a conspicuous nucleus and a perinuclear halo, resembling a plasma cell. However, the osteoblast does not exhibit the clock-face or wheel-like chromatin pattern that is seen in a plasma cell. |
 | Media file 10: Active osteoblasts depositing osteoid on the surface of a woven bone trabecula. Osteoblasts are columnar or cuboidal shaped, with eccentric nuclei and perinuclear halo. These cells also have polarity, with the cytoplasm toward the bone but the nuclei at the end away from the bone. |
 | Media file 11: Osteocytes are present in lacunae; their cytoplasmic processes contact each other through the canaliculi. |
 | Media file 12: Osteoclast in a cytologic preparation (Papanicolaou stain). This image shows multiple nuclei and cytoplasmic processes. |
 | Media file 13: Remodeling of bone. Multiple osteoclasts are sitting in the Howship lacunae, resorbing one side of a bony trabecula, while osteoblasts are depositing new bone on the other side. |
 | Media file 14: Intramembranous ossification. Woven bone arises directly from the surrounding mesenchymal tissue. |
 | Media file 15: Primary calcification center of fetal bone. |
 | Media file 16: Endochondral ossification in a primary ossification center of a fetal chondral model. The chondrocytes are hypertrophic. Early calcification starts in the matrix between the chondrocytes. The surface of the chondral model is covered by perichondrium, which later becomes the periosteum. |
 | Media file 17: Primary spongiosa in the ossification zone of growth plate. The osteoid is deposited at the periphery of calcified cartilage. |
 | Media file 18: The cement line is evidence of a previous remodeling process. |
 | Media file 19: Periosteal bone formation on the surface of cortical bone. New bone is deposited by osteoblasts derived from progenitor cells in the cambium layer of the periosteum. |
 | Media file 20: The articular cartilage can be divided into 3 zones. The calcified zone is separated from the upper zone by a calcified line termed the tidemark. Duplication of the tidemark can be seen with aging, when the calcified cartilage is gradually replaced by endochondral bone formation. Consequently, the calcified zone pushes into the upper zone. |
 | Media file 21: Synovial membrane is partly a smooth connective tissue and partly a villous fibrovascular connective tissue that is lined by a single layer of synovial epithelium. |
 | Media file 22: The meniscus is composed of fibrocartilage. |
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References
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Further Reading
Keywords
osteoblast, osteocyte, osteoclast, haversian system/canal, lamellae, ossification, endosteum, synovium, cartilage, joints, bone growth, bone development
