eMedicine Specialties > Orthopedic Surgery > Neoplasms

Unicameral Bone Cyst: Workup

Author: Charles T Mehlman, DO, MPH, Director, Musculoskeletal Outcomes Research, Associate Professor, Division of Pediatric Orthopedic Surgery, Cincinnati Children's Hospital Medical Center
Contributor Information and Disclosures

Updated: Apr 8, 2008

Workup

Laboratory Studies

  • The diagnosis of a UBC is strongly suspected based upon its typical radiographic appearance and is confirmed when an appropriate cyst fluid is demonstrated. Specific laboratory tests are not a routine part of the workup of a UBC.8,29,30,31

Imaging Studies

  • Plain radiographs
    • Appropriate imaging studies for a UBC should always include plain radiographs.
    • The plain radiograph appearance of the lesion is virtually diagnostic.
    • A particular radiographic sign (ie, fallen-fragment sign) is, at times, very helpful in the radiographic diagnosis of a UBC. Reynolds is credited with describing this sign in 1969.32
      • Typically, the sign is identified when the patient with a UBC presents with a pathologic fracture. The interior of the bone cyst may have complete or nearly complete thin bony septations within the cyst.
      • At the time of pathologic fracture, a portion of one of these bony segments may actually break free and float to the bottom of the cyst. This is possible because the UBC is filled with fluid and is not a solid. The fallen-fragment sign is found in approximately 20% of patients who present with a pathologic fracture secondary to a UBC.33,34
      • Some authors have altered the original description of this sign and refer to it as the fallen-leaf sign as they choose to imagine the broken fragment of bone gently wafting down from the top of the cyst to the bottom of the cyst as if it were a leaf slowly falling to earth from a tree.
  • Magnetic resonance imaging (MRI)35,36,37
    • If a UBC is in close proximity to a growth plate and growth impairment is a concern, MRI may prove to be quite helpful.
    • MRI should not be a routine part of the workup of a UBC. Instead, it should be reserved for unusual or atypical situations. One such instance is a cyst in which growth-plate damage is a concern. Several authors have documented that such damage can occur about the proximal humeral growth plate.
    • Another situation in which preoperative MRI could be of value is in rare cases in which a more sinister diagnosis is suspected, such as in persons with pseudocystic osteosarcoma or low-grade central osteosarcoma. In such instances, MRI is an appropriate part of preoperative staging of such a tumor.
    • A UBC can produce a wide variety of appearances on MRI, including rather heterogeneous fluid signals and even fluid-fluid levels (a sign much more commonly found in aneurysmal bone cysts).

More on Unicameral Bone Cyst

Overview: Unicameral Bone Cyst
Workup: Unicameral Bone Cyst
Treatment: Unicameral Bone Cyst
Follow-up: Unicameral Bone Cyst
Multimedia: Unicameral Bone Cyst
References

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Further Reading

Keywords

UBC, simple bone cyst, solitary bone cyst, bone cyst, solitary unicameral bone cyst, benign bone cyst, essential bone cyst, aneurysmal bone cyst

Contributor Information and Disclosures

Author

Charles T Mehlman, DO, MPH, Director, Musculoskeletal Outcomes Research, Associate Professor, Division of Pediatric Orthopedic Surgery, Cincinnati Children's Hospital Medical Center
Charles T Mehlman, DO, MPH is a member of the following medical societies: American Academy of Pediatrics, American Fracture Association, American Medical Association, American Orthopaedic Foot and Ankle Society, American Osteopathic Association, Arthroscopy Association of North America, North American Spine Society, Ohio State Medical Association, Pediatric Orthopaedic Society of North America, and Scoliosis Research Society
Disclosure: Nothing to disclose.

Medical Editor

Miguel A Schmitz, MD, Consulting Surgeon, Department of Orthopedics, Klamath Orthopedic and Sports Medicine Clinic
Miguel A Schmitz, MD is a member of the following medical societies: American Academy of Orthopaedic Surgeons, American Orthopaedic Society for Sports Medicine, and Arthroscopy Association of North America
Disclosure: Nothing to disclose.

Pharmacy Editor

Francisco Talavera, PharmD, PhD, Senior Pharmacy Editor, eMedicine
Disclosure: eMedicine Salary Employment

Managing Editor

Sean P Scully, MD, PhD, Professor, Department of Orthopedics, University of Miami
Sean P Scully, MD, PhD is a member of the following medical societies: American Academy of Orthopaedic Surgeons, International Society on Thrombosis and Haemostasis, and Society of Surgical Oncology
Disclosure: Nothing to disclose.

CME Editor

Dinesh Patel, MD, FACS, Associate Clinical Professor of Orthopedic Surgery, Harvard Medical School; Chief of Arthroscopic Surgery, Department of Orthopedic Surgery, Massachusetts General Hospital
Dinesh Patel, MD, FACS is a member of the following medical societies: American Academy of Orthopaedic Surgeons, American Association of Physicians of Indian Origin, American College of International Physicians, and American College of Surgeons
Disclosure: Nothing to disclose.

Chief Editor

Harris Gellman, MD, Consulting Surgeon, Broward Hand Center; Voluntary Clinical Professor of Orthopedic Surgery and Plastic Surgery, Departments of Orthopedic Surgery and Surgery, University of Miami School of Medicine
Harris Gellman, MD is a member of the following medical societies: American Academy of Medical Acupuncture, American Academy of Orthopaedic Surgeons, American Orthopaedic Association, American Society for Surgery of the Hand, and Arkansas Medical Society
Disclosure: Nothing to disclose.

 
 
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