eMedicine Specialties > Orthopedic Surgery > Spine
Lumbar Spine Fractures and Dislocations: Treatment
Updated: Jan 8, 2009
Treatment
Medical Therapy
Initial management of lumbar spine injury begins in the field. Any patient in whom a spinal injury is suspected should be placed on a board in a neutral supine position and immobilized in a neck collar for expeditious transportation to a trauma center.26
In the emergency department, all patients should be treated as though they have a spinal injury until spinal injury can be ruled out. The Advanced Trauma Life Support (ATLS) guidelines of the American College of Surgeons should be followed. Stabilization of the patient's airway and hemodynamic status should precede any treatment in order to secure an adequate oxygenation and tissue perfusion. A Foley catheter should be inserted. In patients with neurologic deficit, immediate peritoneal lavage often is advocated to rule out intra-abdominal injuries.27,28 Once the patient has been resuscitated, plain films of the cervical, thoracic, and lumbosacral spine should be obtained.
When possible, a detailed history should be obtained to ascertain the mechanism of injury and the relative force sustained. Individuals who sustain falls often have hyperflexion injuries at the thoracolumbar region in association with pelvic and lower extremity fractures. Persons who wore seat belts during motor vehicle accidents often have distraction injuries or associated cervical spine injuries. In these patients, the vertebrae frequently are compressed or dislocated in the horizontal plane. Crawford et al 29 studied the surgical management of pediatric patients with seat-belt fracture-dislocations of the spine.
Head injuries and extremity fractures commonly accompany vertebral fractures. Abdominal or urological trauma can occur with lumbar fractures, particularly with10 -type injuries.30 The possible presence of concurrent direct injuries to adjacent intracavitary soft tissue structures, such as renal, spleen, or liver lacerations, must be considered. In general, the more caudal the vertebral injury, the greater the biomechanical forces sustained and the greater propensity for injuries to the pelvis and sacrum.
As early as possible and within 8 hours following injury, all patients with spinal cord injuries should receive intravenous methylprednisolone (Solu-Medrol) at 30 mg/kg in a bolus, followed by infusion at 5.4 mg/kg/h for 23 hours. The results of a recent prospective trial demonstrated significantly better motor function and sensation at 6 months and 1 year in patients treated with this regimen compared with those given placebo.
The major goal of treatment in patients with disruption of the vertebral column who are neurologically intact is the prevention of neurologic deterioration. If a fracture is stable without nerve compression, surgical treatment may not be required. For unstable fractures or when neural compression is present, a decompressive procedure with a fusion, usually with instrumentation, becomes necessary. Goals of stabilization are to minimize pain and subsequent spinal deformity.
Compression fractures have a disrupted anterior and intact middle column. Treatment of these injuries depends on the status of the posterior ligamentous structures, as well as on the integrity of the bony elements. A compression of more than 40% of the anterior vertebral wall or a kyphotic deformity of more than 25° is often associated with posterior ligamentous injury. If the kyphotic angulation is less than 25° and the anterior body compression is less than 40% of the vertebral height, the injury can be treated nonoperatively.
The patient is placed in a thoracolumbar orthosis (TLSO) with restriction of activities.31 After 3-4 months in the orthosis, flexion extension radiographs should be obtained. If no motion is present and the deformity has not progressed, the patient can be weaned from the TLSO over several weeks and can start physical therapy for muscle strengthening. If abnormal motion is present, the deformity has progressed, or severe pain persists, surgical stabilization may be required. If the anterior column is compressed more than 40% or the kyphosis exceeds 25°, surgical stabilization is indicated.
In burst fractures, both the anterior and middle columns are disrupted.32,33 The posterior column may or may not be affected. In burst fractures, it is important to analyze the percentage of canal compromise, the degree of angulation, and the neurologic status of the patient.34 If the canal compromise is less than 40%, the patient may require a TLSO brace worn for at least 3 months. Standing lateral radiographs should be obtained on a regular basis to document any interval increase in spinal deformity. If the canal compromise is more than 40%, the kyphotic deformity is more than 25°, or the patient develops neurologic changes (eg, changes in motor function or bladder control, new sensory deficits), surgical intervention may be required. Burst fractures can be reduced and stabilized from an anterior or a posterior approach.35,36 In patients with burst fractures and significant posterior column disruption, anterior and posterior fusion (360°)isindicated.37,38
In patients with fracture-dislocation injuries, all 3 columns of the spine are disrupted. This type of injury carries a high incidence of spinal cord injury. In general, most fracture-dislocation injuries require surgical treatment. If a patient with a fracture-dislocation has normal neurologic examination findings, the spine must be stabilized to prevent a spinal cord, cauda equina, or nerve root injury. When the patient has an incomplete spinal cord injury from a fracture-dislocation, the spinal canal should be decompressed and the spine stabilized to prevent neurologic deterioration. Stabilization of the spine in patients with a complete neurologic deficit from a fracture-dislocation may prevent progressive kyphotic deformation, allowing early mobilization and rehabilitation, thereby minimizing the hospital length of stay.
Surgical Therapy
The decision to perform surgery in the acute setting is determined by the surgeon, depending on the stability of the fracture, the radiologic evidence of spinal cord or cauda equina compression, the patient's neurologic examination, and the overall status of the patient. In general, decompressive surgery is not indicated for patients with complete deficit lasting more than 48 hours and is advocated for patients with partial cord or cauda equina injuries.
The relationship between the timing of surgical decompression and neurologic outcome has been widely debated. Some evidence in the literature suggests that acute surgical therapy decreases the length of hospitalization and related costs, facilitating rehabilitation in many patients with spine injury.
Numerous factors must be considered in the selection of the surgical approach, including the degree of bone destruction, associated ligamentous injury, presence and degree of neurologic deficit, age and medical condition of the patient, and associated injuries.
Preoperative Details
The surgical procedure usually is performed under general anesthesia with the patient in a prone, lateral, or knee-elbow position. After the patient is under general anesthesia and the endotracheal tube is secured, the patient's eyes should be well lubricated and taped shut. For a posterior approach, the author's preference is to perform the procedure under general anesthesia with the patient in the prone position over gel rolls that extend from the shoulders to the lower pelvis, or using a Wilson frame.
The use of a radiolucent Wilson frame on a Jackson table is recommended because it maintains the spine in lordosis and avoids increased intra-abdominal pressure. Increase in intra-abdominal pressure increases venous pressure to the epidural veins, resulting in increased epidural bleeding. The use of intraoperative spinal cord monitoring of the somatosensorial evoked potential and electromyography is recommended to minimize the risk of further neurologic deficits. The authors prefer the use of the operative microscope, which allows increased illumination and visibility.
Intraoperative Details
Surgical decompression
The preferred posterior skin incision is midline. The length of the incision should permit complete visualization of the entire hemilamina rostral and caudad to the appropriate interlaminar space or spaces, as well as the entire facet complex. The lumbodorsal fascia is incised with the electric knife just lateral to the spinous process and supraspinous ligament. Atraumatic dissection of the muscles off the spinous processes, laminae, and transverse processes is accomplished with a periosteal elevator and electric knife. After exposing the appropriate interlaminar area, a self-retaining retractor is used to retract the musculofascial layers. Posterior element fractures usually are visualized at this time.
If compression of neural structures has been determined preoperatively, adequate bilateral exposure and decompression of ligaments and bone are then performed with a high-speed drill, rongeurs, and Kerrison punches and carried both rostrad and caudad well beyond the area of neurocompressive pathology. All residual ligamentum flavum is gently microdissected from the dura and nerve root sheath and excised with either a 2- or 3-mm thin-footplate Kerrison rongeur. Once adequate dorsolateral decompression and exposure of the dural sac and involved nerve root have been accomplished, a generous foraminotomy is accomplished with the thin-plate Kerrison rongeur.
Posterior intertransverse fusion
The spine is exposed through a posterior midline incision and subperiosteal muscle dissection. The incision length must be adequate to fully expose the transverse processes. The dissection is carried out laterally over the facet joint to completely expose the transverse processes at the levels to be fused. All soft tissue is meticulously removed from the grafting area, including the transverse process, lateral aspect of the superior facet joints, and pars interarticularis.
The bone graft can be harvested through the previously made midline incision or through the separately placed lateral incision. The superior and outer margins of the iliac crest are exposed subperiosteally. Multiple corticocancellous strips are harvested.
Following adequate bone harvest, the donor bed is copiously irrigated with antibiotic solution and waxed to reduce blood loss. This wound is closed in layers. Decortication of the graft bed usually is performed with a high-speed drill. The harvested bone then is placed onto the recipient bone bed and packed into the facet joints. The wound is copiously irrigated and closed with an absorbable suture.
The intertransverse process region provides ample surface area for graft contact, which results in a high rate of fusion. Exposure of this region requires substantial paraspinal muscle dissection, which can be bloody and time consuming. This technique does not decrease immediate motion, correct deformity, or maintain spinal alignment and generally is used in conjunction with pedicle screw placement.
Posterior interbody fusion
Lumbar interbody fusion remains a popular method of arthrodesis because it allows access to the anterior weightbearing spinal column through a standard posterior laminectomy.39 This technique seems most ideally suited for cases of mechanical instability that require concomitant spinal canal or disk space entry for decompression. Patient position and initial spinal exposure are similar to that described for intertransverse process fusion. The dissection need only be carried out to the lateral aspect of the facet joints.
A standard bilateral laminectomy or bilateral heminectomies are performed. Removal of the medial two thirds of the facet joints adequately exposes the disk space for graft placement. Epidural veins are cauterized and divided. A wide opening is made into the annulus, and the disk is removed. Sharp osteotomes and ring curets are used to remove the cartilaginous endplates. Bone grafts or implants filled with bone graft are impacted into the disk space and levered medially until 60-80% of the central disk space volume has been filled. The use of this technique in the paramedial space is known as posterior lateral interbody fusion, whereas a more lateral approach is known as transpedicular interbody fusion.40,41
Anterior corpectomy and fusion
Various approaches to the anterior lumbar and lumbosacral spine have been described. Proper exposure of the anterior lumbar spine requires a detailed knowledge of the neurovascular soft tissue surrounding the anterior spine. Following incision of the abdominal wall musculature, the peritoneal sac is bluntly freed from its attachment to the transversalis fascia until the spine and psoas muscle are identified. The ureter usually remains attached to the posterior peritoneum and is elevated away from the spine during the dissection. It must be identified and protected before any sharp dissection is performed.
A 37-year-old man who underwent an anterior approach for an unstable L1 burst fracture. A corpectomy was performed, with a vertebral reconstruction with Harms cages and a screw to stabilize the cage. The patient subsequently underwent a posterior arthrodesis with iliac crest bone graft and transpedicular screw placement.
The aorta overlies the anterior aspect of the spine and bifurcates into common iliac arteries at about the L4-L5 disk space. The inferior vena cava is dorsolateral to the aorta on the right side, and the left common iliac vein crosses the midline behind the iliac arteries and may partially overlie the L5-S1 disk space. Segmental arteries and veins run transversely at the midvertebral body level to enter the aorta and vena cava, respectively. These vessels need to be suture ligated in order to reflect the great vessels for exposure of the spine. The lumbar sympathetic chain descends just medial to the psoas muscle and can be identified easily. Once adequate exposure has been achieved, self-retaining retractors are used. Injury to the great vessels is a common complication of surgery. Therefore, these vessels must be adequately protected during this dissection.
Localization of the vertebral fracture is performed using a cross table lateral radiograph. Once the correct level has been exposed, the superior and inferior disks are removed using a long knife, rongeurs, curets, and osteotomes. The vertebral corpectomy is performed using a high-speed drill, curettes, osteotomes, and rongeurs with special care when approaching the spinal canal. Once adequate decompression has been achieved, the cartilaginous endplates are removed down to bleeding subchondral bone. Spinal fixation is placed in the adjacent vertebral bodies, and gentle distraction of the corpectomy is achieved with a distractor. Various donor bone sources are available. The authors prefer to use humerus, femur, or a tibial strut allograft. This can be combined with local autogenous bone from the corpectomy. Autogenous anterior iliac crest bone graft can also be used.
The bone graft is carefully shaped to maximize bone contact area and is impacted into the space provided by the corpectomy. The distraction then is removed, further securing the bone graft. A titanium plate or rods are placed on the bolts securing the graft in position. The retractors are removed, and the wound is then closed in layers.39
Reported fusion rates and clinical success with anterior interbody techniques are widely variable. Differences probably are related to surgical technique, source of donor bone, patient selection, and method by which determination of fusion was evaluated. Internal fixation and direct current electrical stimulation probably enhance fusion rates.42
Posterior internal fixation with pedicle screws
Internal fixation as an adjunct to spinal fusion has become increasingly popular in recent years. Titanium rods are longitudinally anchored to the spine by hooks or transpedicular screws. Powerful forces can be applied to the spine through these implants to correct deformity. Implants provide immediate rigid spinal immobilization, which allows for early patient mobilization, and provides a more optimal environment for bone graft incorporation. Numerous clinical and experimental studies demonstrate higher fusion rates in patients with rigid internal fixation than in controls without instrumentation.
Postoperative lateral radiograph; although the patient was paraplegic, in order to prevent severe kyphotic deformity of the spine and to allow a rapid mobilization, a posterior arthrodesis was performed with pedicle screws, hooks, and rods.
Although various implants are available, pedicle fixation systems are the most commonly used implant type in the lumbosacral spine. The large size of the lumbar pedicles minimizes the number of instrumented motion segments required to achieve adequate stabilization. The technique of pedicle fixation requires a thorough knowledge of the pedicle anatomy.43
Several techniques are available for screw placement, but the authors prefer an entry point into the pedicle at the intersection of the middle of the transverse process, the facet joint, and the pars.44 Once a screw trajectory has been achieved within a pedicle finder, palpation of the cortical margins of the screw tract with a ball tip finder minimizes the penetration of the screw into the spinal canal. A tap is then used to create the threads for the screws. Finally, the screws can be placed under continuous fluoroscopic guidance. A depth of 50-75% of the AP vertebral body diameter is usually recommended for lumbar fixation, while bicortical screw purchase is recommended for sacral fixation. The position of the screws is then assessed electrophysiologically with a nerve stimulator and radiologically with an AP, lateral, and 2-dimensional scan of the spine performed with an isocentric C arm.
Kyphoplasty
Compression fractures with an intact posterior cortical wall can be treated by means of a kyphoplasty. It consists of the transpedicular placement of a balloon through a bone biopsy needle and canula into the compressed vertebral body under fluoroscopic guidance. The balloon is then inflated under controlled pressure, resulting in expansion of the vertebral body and creation of a cavity. The cavity created is then filled with bone cement. This procedure results in elevation of the endplate and stabilization the fracture fragments, with a consequent reduction of pain.45,46 A posterior cortical defect in a burst fracture is considered a contraindication for kyphoplasty. For a comparison of vertebroplasty and kyphoplasty, see Hiwatashi et al47 and Karlsson et al.48
Patients with compression fractures not compromising the spinal canal can be treated by means of a kyphoplasty. The use of a percutaneous balloon allows for expansion of the fractured vertebrae. Then, the void created by the balloon is filled with bone cement
Patients with an acute compression fracture treated with kyphoplasty. AP and lateral views demonstrate a good expansion of the compressed vertebral body and nice feeling with cement.
A 47-year-old man was involved in a motor vehicle accident. He arrived at the hospital with paraplegia but preserved sensation in both lower extremities. He was immediately taken to surgery for an open reduction of the fracture, decompression of the cauda equine, and arthrodesis of the spine. He regained motor function following the surgery.
Postoperative Details
Significant postoperative discomfort limits activity for several days in most patients. A morphine patient-controlled analgesia pump usually is employed during the first 36-48 hours. A molded lumbar or thoracolumbar orthosis is often worn for 3 months.
During the postoperative period, patients with fractures that have resulted in neurologic deficits are prone to multiple complications including skin decubitus, pulmonary problems, and urinary sepsis (see Complications).
Nursing care should include frequent repositioning, vigorous pulmonary toilet, and deep venous thrombosis (DVT) prophylaxis. Intermittent pneumatic compression stockings are indicated for all patients with spinal injuries. If the patient is neurologically intact, pulsatile stockings alone suffice. However, if the patient has neurologic compromise, pulsatile stockings and low-dose subcutaneous heparin combined are used to prevent DVT. If the patient is immobilized from multiple injuries, heparin should be started after the second postoperative day, even in patients who are neurologically intact.
Intermittent catheterization should be performed in patients with spinal cord injuries and urinary retention. A bowel regimen consisting of stool softeners and suppositories always should be instituted in these patients.
Follow-up
The fusion is evaluated with plain radiographs, including flexion and extension views, at 6 weeks, 3 months, and 6 months postoperatively. If in doubt, a CT scan is performed.
Complications
Patients with spinal cord injuries are prone to multiple complications, including decubitus ulcers, pulmonary problems, urinary sepsis, and new fractures49 . Occasionally, patients develop delayed progressive neurologic deterioration months to years after sustaining spinal trauma as a result of instability and progressive spinal deformation.
Intraoperative complications
Neurologic deterioration can occur from neural traction, compression, or interruption of the vascular supply to the neural elements. The overall risk of neurologic injury from posterior instrumentation is 1-3%. In addition, postoperative neurologic deterioration may occur from graft dislodgment, displacement of the hardware, or hematomas.
Intraoperative injury to major vessels and viscera may occur during vertebral exposure and reconstruction. Dural tears, which may be the result of bone fragments or may occur during the surgical approach, can result in cerebrospinal fluid leaks.
Failure of the fusion
Pseudarthrosis is a cause of chronic pain as result of the malunion of the fusion. It may lead to progressive deformity, neural compromise, and pain. Failure of the instrumentation, such as dislodgment or breakage, is usually related to pseudarthrosis.
Infections
Infections can occur following spine surgery, especially following a long surgical procedure for a complicated instrumentation placement. Superficial infections should be opened and debrided. The wound may be packed open or closed using retention sutures. Appropriate antibiotics should be employed, starting with coverage against gram-positive coccus and adjusting according to culture results. All attempts should be made to keep the instrumentation and graft in place until the fusion is solid.
Thromboembolic disease
DVT is a significant potential complication in patients with spinal fractures. Thromboembolism has been reported to occur in as many as 70% of patients with complete motor paralysis. Pulmonary embolism (PE) significantly affects the probability of survival following a spinal fracture. Mortality rates for patients with PE have not decreased significantly in the last 30 years, emphasizing the need for more effective preventive measures. Recommendations for prophylaxis are varied and usually include subcutaneous or low molecular weight heparin, sequential compression stockings, and elastic hose placed on the lower extremities. Patients who develop DVT should be treated aggressively with anticoagulation. If the risk for systemic anticoagulation is prohibitive, options include thrombectomy or a cava vein filter.
Stress ulcers
The stress resulting from a traumatic injury, a complicated surgery, and mechanical ventilation can predispose a patient to gastric ulcers. However, the widespread use of prophylaxis measures, such as H2 blockers, sucralfate, and proton pump inhibitors, has reduced the incidence of severe bleeding from stress ulcers.
Adynamic ileus and Ogilvie syndrome
Ogilvie syndrome, also known as pseudoobstruction of the colon, is characterized by massive abdominal distention with a cecal diameter of more than 9 cm. Nausea, vomiting, diarrhea, and severe abdominal distention are common symptoms.
Preventive measures for both conditions include minimizing bed rest, returning to ambulation as early as possible, and limiting the use of narcotics. Early recognition and treatment of these conditions are essential to reduce morbidity and mortality. Initial treatment includes cessation of oral intake, nasogastric suction, insertion of rectal tubes, and cessation of narcotics.
Genitourinary complications
Urinary complications continue to be significant sources of morbidity following spinal injuries. In patients with spinal cord injuries, distention of the bladder can lead to autonomic dysreflexia, impairment of bladder sensation, detrusor hyperreflexia, and sphincter dyssynergia, which can lead to renal damage from hydronephrosis or vesicourethral reflux. These complications are decreased with indwelling Foley catheters. In patients with spinal cord injury, the most frequent source of morbidity is sepsis related to urinary tract infections.
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Keywords
lumbar spine fractures and dislocations, lumbar spine trauma, spinal fractures, acute spinal injuries, lumbar vertebral fractures, lumbar compression fracture, thoracolumbar injuries, lumbar injuries, osteoporosis, paraplegia, tetraplegia, spinal cord injury, broken back, chance fracture










Treatment: Lumbar Spine Fractures and Dislocations