Laboratory Studies
- Erythrocyte sedimentation rate (ESR), antinuclear antibody (ANA), rheumatoid factor (RF)
- The ESR, ANA, and RF tests should all be ordered in cases in which autoimmune disease is suspected, because these inflammatory disorders can trigger bursitis.
- Fluid analysis
- The joint should be aspirated and fluid sent for analysis to rule out infectious or rheumatic causes. Bursal fluid should be drawn for uric acid crystal determination, cell count with differential, Gram stain, and culture. Nonseptic bursitis has cell counts less than 2000, with a predominance of mononuclear cells. Septic bursitis has cell counts greater than 70,000, with a predominance of polymorphonuclear cells. Gram stain and culture are done to identify any pathogens.
Imaging Studies
- Radiographs
- Plain radiographs may be useful in identifying osteophytes or other underlying bony pathology that may be triggering the bursal inflammation. They may also show joint effusions.
- Bone scan
- Bone scan is not a sensitive test of bursitis, but it may be done in cases in which the diagnosis is unclear, to rule out other causes of pain.
- MRI and CT scan
- MRI and CT are usually not necessary because of the common clinical presentation of bursitis. MRI is useful to delineate the anatomy of the entire joint and is a very sensitive test for identification of bursitis. MRI is also helpful in ruling out suspected solid tumors and defining pathology for possible surgical excision.
- Ultrasonography
- Ultrasonography is a useful modality to obtain further imaging of the bursa when the diagnosis is uncertain, and it is often used to obtain images of popliteal cysts. These bursae are often discovered incidentally when lower-extremity Doppler studies are done to rule out deep vein thrombosis. Ultrasound studies distinguish solid from cystic masses and are helpful in detecting Baker's cysts (popliteal bursitis) when there are extensive joint deformities.[11, 24]
Crenshaw AH, Canale ST. Nontraumatic disorders. In: Canale ST, ed. Campbell's Operative Orthopaedics. 9th ed. St Louis, Mo:. Mosby; 1998:776-85.
DeLee JC, Drez D. Imaging effusions, cysts, and ganglia. In: DeLee JC, Drez D, Miller MD, eds. DeLee and Drez's Orthopaedic Sports Medicine: Principles and Practice. Philadelphia, Pa: WB Saunders;. 2003: 1646-8.
Sheon RP, Moskowitz RW, Goldberg VM. Soft Tissue Rheumatic Pain: Recognition, Management, Prevention. 3rd ed. Baltimore, Md: Williams and Wilkins;. 1996.
Farmer KW, Jones LC, Brownson KE, Khanuja HS, Hungerford MW. Trochanteric Bursitis After Total Hip Arthroplasty Incidence and Evaluation of Response to Treatment. J Arthroplasty. Mar 3 2009;[Medline].
Pretell J, Ortega J, García-Rayo R, Resines C. Distal fascia lata lengthening: an alternative surgical technique for recalcitrant trochanteric bursitis. Int Orthop. Oct 2009;33(5):1223-7. [Medline].
Martinez-Taboada VM, Cabeza R, Cacho PM, Blanco R, Rodriguez-Valverde V. Cloxacillin-based therapy in severe septic bursitis: Retrospective study of 82 cases. Joint Bone Spine. Jul 1 2009;[Medline].
Reilly JP, Nicholas JA. The chronically inflamed bursa. Clin Sports Med. Apr 1987;6(2):345-70. [Medline].
Hirji Z, Hunjun JS, Choudur HN. Imaging of the bursae. J Clin Imaging Sci. 2011;1:22. [Medline]. [Full Text].
Salzman KL, Lillegard WA, Butcher JD. Upper extremity bursitis. Am Fam Physician. Nov 1 1997;56(7):1797-806, 1811-2. [Medline].
Chen MJ, Lew HL, Hsu TC, Tsai WC, Lin WC, Tang SF. Ultrasound-guided shoulder injections in the treatment of subacromial bursitis. Am J Phys Med Rehabil. Jan 2006;85(1):31-5. [Medline].
Blankstein A, Ganel A, Givon U, Mirovski Y, Chechick A. Ultrasonographic findings in patients with olecranon bursitis. Ultraschall Med. Dec 2006;27(6):568-71. [Medline].
Turan H, Serefhanoglu K, Karadeli E, Timurkaynak F, Arslan H. A case of brucellosis with abscess of the iliacus muscle, olecranon bursitis, and sacroiliitis. Int J Infect Dis. Apr 23 2009;[Medline].
Malkin J, Shrimpton A, Wiselka M, Barer MR, Duddridge M, Perera N. Olecranon bursitis secondary to Mycobacterium kansasii infection in a patient receiving infliximab for Behcet's disease. J Med Microbiol. Mar 2009;58:371-3. [Medline].
Butcher JD, Salzman KL, Lillegard WA. Lower extremity bursitis. Am Fam Physician. May 15 1996;53(7):2317-24. [Medline].
Keplinger FS, Gupta N. Knee bursitis. In: Frontera WR, Silver JK, eds. Essentials of Physical Medicine and Rehabilitation. Philadelphia, Pa: Hanley & Belfus;2002: 340-4.
McAfee JH, Smith DL. Olecranon and prepatellar bursitis. Diagnosis and treatment. West J Med. Nov 1988;149(5):607-10. [Medline].
Brinks A, van Rijn RM, Bohnen AM, Slee GL, Verhaar JA, Koes BW. Effect of corticosteroid injection for trochanter pain syndrome: design of a randomised clinical trial in general practice. BMC Musculoskelet Disord. Sep 19 2007;8(1):95. [Medline].
Alvarez-Nemegyei J, Canoso JJ. Evidence-Based Soft Tissue Rheumatology: III: Trochanteric Bursitis. J Clin Rheumatol. Jun 2004;10(3):123-124. [Medline].
Rowand M, Chambliss ML, Mackler L. Clinical inquiries. How should you treat trochanteric bursitis?. J Fam Pract. Sep 2009;58(9):494-500. [Medline].
Viradia NK, Berger AA, Dahners LE. Relationship between width of greater trochanters and width of iliac wings in tronchanteric bursitis. Am J Orthop (Belle Mead NJ). Sep 2011;40(9):E159-62. [Medline].
Alvarez-Nemegyei J. Risk factors for pes anserinus tendinitis/bursitis syndrome: a case control study. J Clin Rheumatol. Apr 2007;13(2):63-5. [Medline].
Alvarez-Nemegyei J, Canoso JJ. Evidence-Based Soft Tissue Rheumatology IV: Anserine Bursitis. J Clin Rheumatol. Aug 2004;10(4):205-206. [Medline].
Wiegerinck JI, Kok AC, van Dijk CN. Surgical treatment of chronic retrocalcaneal bursitis. Arthroscopy. Feb 2012;28(2):283-93. [Medline].
Tsai YH, Huang TJ, Hsu WH, Huang KC, Li YY, Peng KT. Detection of subacromial bursa thickening by sonography in shoulder impingement syndrome. Chang Gung Med J. Mar-Apr 2007;30(2):135-41. [Medline].
Buchbinder R, Green S, Youd JM, Johnston RV. Oral steroids for adhesive capsulitis. Cochrane Database Syst Rev. 2006;(4):CD006189. [Medline].
Hong JY, Yoon SH, Moon do J, Kwack KS, Joen B, Lee HY. Comparison of high- and low-dose corticosteroid in subacromial injection for periarticular shoulder disorder: a randomized, triple-blind, placebo-controlled trial. Arch Phys Med Rehabil. Dec 2011;92(12):1951-60. [Medline].
Baker CL Jr, Massie RV, Hurt WG, Savory CG. Arthroscopic bursectomy for recalcitrant trochanteric bursitis. Arthroscopy. Aug 2007;23(8):827-32. [Medline].
Baums MH, Spahn G, Nozaki M, Steckel H, Schultz W, Klinger HM. Functional outcome and general health status in patients after arthroscopic release in adhesive capsulitis. Knee Surg Sports Traumatol Arthrosc. May 2007;15(5):638-44. [Medline].

