Updated: Apr 20, 2009
Hester et al first described the central pedicle reduction technique in 1985.1 The principle of this technique is to preserve the breast volume where maximum projection is desired. Evolution of the technique has resulted in the current technique described here.2,3
Macromastia or mammary hyperplasia is the condition of large breast size out of proportion to a woman's body habitus that is associated with symptoms including back, neck, and shoulder pain. Macromastia is a common condition treated by plastic surgeons.
Reduction mammaplasty is one of the 5 most frequently performed reconstructive operations. According to the American Society of Aesthetic Plastic Surgeons (ASPS), more than 153,087 breast reduction procedures were performed in 2007 up from 47,874 in 1997.4 The ASPS/Plastic Surgery Educational Foundation (PSEF) procedural data from 2007 lists 105,706 cases of reduction mammaplasty, up from 39,639 cases in 1992.5
Etiology is unknown.
The precise pathophysiology of macromastia is unclear.6 End-organ hypersensitivity to hormonal stimulation appears to play a role. With the onset of menarche and hormonal production, breast growth and, in some cases, hypertrophy can be seen. Some patients present with macromastia following pregnancy; others see exacerbation of macromastia related to weight gain or obesity.7,8
Preoperative assessment includes a standard history and physical examination, with special attention directed to breast history and health, including family history of breast cancer. Preoperative photos should be taken and reviewed with the patient to point out conditions such as preexisting asymmetry. Representative before and after photos also should be reviewed if available to ensure that the patient understands the scars and has realistic expectations.
Macromastia is a common condition treated by plastic surgeons. Because women have various body shapes and sizes, and rules regarding insurance coverage vary from region to region, no universally accepted definition of macromastia that requires surgery exists. However, definite symptoms exist, which have been documented by numerous authors including Hagerty, Shewmake, and Gonzalez among many others.9,10,11 Most commonly, these symptoms consist of upper back and neck pain, breast pain, shoulder grooving from bra straps, and inframammary intertrigo.
In an effort to relieve these symptoms of pain, a number of surgical techniques for reduction mammaplasty have been described using various pedicles and skin resections.12,13,14,15,16,17,18,19 The ideal breast reduction results in complete relief of symptoms while maintaining normal sensation and the ability to lactate. Additionally, the operation should result in an aesthetically pleasing breast shape with minimal scarring and a low complication rate. Lastly, most or all of these objectives should be achieved in a time-efficient and cost-efficient manner.
The female breast consists of the glandular breast mound and the axillary tail of Spence. The nipple-areola complex (NAC) is the most prominent anatomic feature on the breast. It has important relations to the underlying glandular tissue.
The first of these relations consists of the blood supply to the NAC, which enters through the glandular breast tissue but also receives contributions from the subdermal plexus of the breast skin.
The second important anatomic relationship between the glandular breast tissue and the NAC is that of innervation. The nipple lies in the dermatome of the fourth intercostal nerve. Additional innervation is contributed by adjacent dermatomes. No clear anatomic distinction has been identified for innervation contributing erogenous versus tactile sensation.
Lastly, one must consider the communication between the lactiferous ducts of the glandular breast tissue and the nipple. Clearly, the importance of this depends upon the patient's childbearing status and any prior demonstration of the ability (or inability) to lactate.
Contraindications to breast reduction surgery are similar to contraindications to any elective surgical procedure, including cardiac and pulmonary considerations. Fortunately, most women seeking breast reduction surgery are often young and in otherwise good health. Since the operation is performed to relieve symptoms and not to treat a life- or limb-threatening disease, use common sense regarding general anesthetic risks. Smoking, diabetes, and obesity have been associated with increased complication rates, including nipple necrosis.
Complications are usually minimal and may consist of seroma and small areas of wound separation (especially at the 3-way junction of the inverted T incision). Nipple areola loss should be approximately 1% and is frequently associated with loss of underlying glandular breast tissue.20,21,22 Loss of sensation is an uncommon problem with the use of a central glandular technique, as it safely preserves the nerve distribution to the nipple.23,24 Loss of the capacity to lactate postoperatively has been demonstrated to be unusual with various pedicles.25
All of these problems should be treated conservatively with frequent office visits for reassurance. In the case of nipple loss, corrective surgery is usually required but should be deferred for several months until edema has resolved and any compromised tissue has been debrided. Obesity and smoking have been identified as increasing the risks for complications following reduction mammaplasty and should be avoided, if possible, to reduce complications.26,27,28
In a reported series of 153 patients, presenting symptoms were back and neck pain, shoulder grooving, and intertrigo.2 An average of 794 g was reduced per side. One case of nipple areola loss occurred in 306 breasts. Wound healing complications (usually a small dehiscence at the inverted T incision) were observed in 24 patients, and all but one of these complications were managed by local wound care alone. Minor revisions under local anesthesia were required in 13 patients. Patient satisfaction and relief of symptoms were high. Other authors have also shown the efficacy of symptomatic relief.29,30,31 In addition, satisfactory aesthetic outcomes can be achieved with this technique.
A multitude of breast reduction techniques has been described over the years. Variations of the inferior pedicle technique are the most common procedures in use today.32,33,34 Certainly, no single best operative technique exists for reduction mammaplasty. The authors' intention in this article is to illustrate one technique and to present results from a representative series of patients. For information on other breast reduction techniques, see the following eMedicine Plastic Surgery articles:
Hester TR Jr, Bostwick J 3rd, Miller L, Cunningham SJ. Breast reduction utilizing the maximally vascularized central breast pedicle. Plast Reconstr Surg. Dec 1985;76(6):890-900. [Medline].
Grant JH 3rd, Rand RP. The maximally vascularized central pedicle breast reduction: evolution of a technique. Ann Plast Surg. Jun 2001;46(6):584-9. [Medline].
Cho BC, Yang JD, Baik BS. Periareolar reduction mammoplasty using an inferior dermal pedicle or a central pedicle. J Plast Reconstr Aesthet Surg. 2008;61(3):275-81. [Medline].
Surgical and Nonsurgical Procedures: 11-year Comparison, 1997-2007 [database online]. http://www.surgery.org: American Society of Aesthetic Plastic Surgeons; 6/23/08. Updated 6/23/08.
2007 Reconstructive Plastic Surgery Trends 1992, 2006, 2007 [database online]. www.plasticsurgery.org: American Society of Plastic Surgeons; 6/23/08. Updated 6/23/08.
de la Torre JI, Vasconez LO. Macromastia and Reduction Mammaplasty. In: Bland KI, Copeland EM. The Breast. Vol 2. 3rd ed. St. Louis, Mo: Saunders; 2004:43. [Full Text].
Ayan F, Sakoglu N, Paksoy M, As A, Dogan M. Pregnancy-induced macromastia. Breast J. Sep-Oct 2004;10(5):448. [Medline].
Cruz-Korchin N, Korchin L, González-Keelan C, Climent C, Morales I. Macromastia: how much of it is fat?. Plast Reconstr Surg. Jan 2002;109(1):64-8. [Medline].
Hagerty RC, Hagerty RF. Reduction mammaplasty: central cone technique for maximal preservation of vascular and nerve supply. South Med J. Feb 1989;82(2):183-5. [Medline].
Shewmake KB. Reduction mammaplasty and mastopexy. Selected Readings in Plast Surg. 1994;7:30:1-27.
Gonzalez F, Walton RL, Shafer B, et al. Reduction mammaplasty improves symptoms of macromastia. Plast Reconstr Surg. Jun 1993;91(7):1270-6. [Medline].
Courtiss EH, Goldwym RM. Reduction mammaplasty by the inferior pedicle technique. An alternative to free nipple and areola grafting for severe macromastia or extreme ptosis. Plast Reconstr Surg. Apr 1977;59(4):500-7. [Medline].
McKissock PK. Reduction mammaplasty by the vertical bipedicle flap technique. Rationale and results. Clin Plast Surg. Apr 1976;3(2):309-20. [Medline].
McKissock PK. Invited discussion: Breast reduction utilizing the maximally vascularized central breast pedicle. Plast Reconstr Surg. 1985;76:899-900.
Parenteau JM, Regnault P. The Regnault "B" technique in mastopexy and breast reduction: a 12-year review. Aesthetic Plast Surg. Spring 1989;13(2):75-9. [Medline].
Yousif NJ, Larson DL, Sanger JR, Matloub HS. Elimination of the vertical scar in reduction mammaplasty. Plast Reconstr Surg. Mar 1992;89(3):459-67; discussion 468. [Medline].
Reus WF, Mathes SJ. Preservation of projection after reduction mammaplasty: long-term follow-up of the inferior pedicle technique. Plast Reconstr Surg. Oct 1988;82(4):644-52. [Medline].
Moufarrege R, Beauregard G, Bosse JP, et al. Reduction mammoplasty by the total dermoglandular pedicle. Aesthetic Plast Surg. 1985;9(3):227-32. [Medline].
Wise RJ. A preliminary report on a method of planning the mammaplasty. Plast Reconstr Surg. May 1956;17(5):367-75. [Medline].
Brown DM, Young VL. Reduction mammoplasty for macromastia. Aesthetic Plast Surg. 1993;17(3):211-23. [Medline].
Nahabedian MY, McGibbon BM, Manson PN. Medial pedicle reduction mammaplasty for severe mammary hypertrophy. Plast Reconstr Surg. Mar 2000;105(3):896-904. [Medline].
Chang P, Shaaban AF, Canady JW, Ricciardelli EJ, Cram AE. Reduction mammaplasty: the results of avoiding nipple-areolar amputation in cases of extreme hypertrophy. Ann Plast Surg. Dec 1996;37(6):585-91. [Medline].
Schlenz I, Rigel S, Schemper M, Kuzbari R. Alteration of nipple and areola sensitivity by reduction mammaplasty: a prospective comparison of five techniques. Plast Reconstr Surg. Mar 2005;115(3):743-51; discussion 752-4. [Medline].
Hamdi M, Blondeel P, Van de Sijpe K, et al. Evaluation of nipple-areola complex sensitivity after the latero-central glandular pedicle technique in breast reduction. Br J Plast Surg. Jun 2003;56(4):360-4. [Medline].
Cruz NI, Korchin L. Lactational performance after breast reduction with different pedicles. Plast Reconstr Surg. Jul 2007;120(1):35-40. [Medline].
Gamboa-Bobadilla GM, Killingsworth C. Large-volume reduction mammaplasty: the effect of body mass index on postoperative complications. Ann Plast Surg. Mar 2007;58(3):246-9. [Medline].
Setälä L, Papp A, Joukainen S, Martikainen R, Berg L, Mustonen P, et al. Obesity and complications in breast reduction surgery: are restrictions justified?. J Plast Reconstr Aesthet Surg [serial online]. Nov 24 2007;[Medline]. Available at http://www.sciencedirect.com/science/journal/17486815.
Chan LK, Withey S, Butler PE. Smoking and wound healing problems in reduction mammaplasty: is the introduction of urine nicotine testing justified?. Ann Plast Surg. Feb 2006;56(2):111-5. [Medline].
Spector JA, Singh SP, Karp NS. Outcomes after breast reduction: does size really matter?. Ann Plast Surg. May 2008;60(5):505-9. [Medline].
Iwuagwu OC. Effects of reduction mammaplasty on pulmonary function and symptoms of macromastia. Plast Reconstr Surg. Dec 2003;112(7):1969-70; author reply 1970. [Medline].
O'Blenes CA, Delbridge CL, Miller BJ, Pantelis A, Morris SF. Prospective study of outcomes after reduction mammaplasty: long-term follow-up. Plast Reconstr Surg. Feb 2006;117(2):351-8. [Medline].
Balch CR. The central mound technique for reduction mammaplasty. Plast Reconstr Surg. Mar 1981;67(3):305-11. [Medline].
Georgiade NG, Serafin D, Morris R, Georgiade G. Reduction mammaplasty utilizing an inferior pedicle nipple-areolar flap. Ann Plast Surg. Sep 1979;3(3):211-8. [Medline].
Ribeiro L, Accorsi A Jr, Buss A, Marcal-Pessoa M. Creation and evolution of 30 years of the inferior pedicle in reduction mammaplasties. Plast Reconstr Surg. Sep 1 2002;110(3):960-70. [Medline].
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Jorge I de la Torre, MD, FACS, Professor of Surgery and Physical Medicine and Rehabilitation, Residency Program Director, Division of Plastic Surgery, University of Alabama at Birmingham; Director, Center for Advanced Surgical Aesthetics
Jorge I de la Torre, MD, FACS is a member of the following medical societies: American Association of Plastic Surgeons, American Burn Association, American College of Surgeons, American Medical Association, American Society for Laser Medicine and Surgery, American Society for Reconstructive Microsurgery, American Society of Maxillofacial Surgeons, American Society of Plastic Surgeons, Association for Academic Surgery, and Medical Association of the State of Alabama
Disclosure: Nothing to disclose.
James Neal Long, MD, Assistant Professor of Plastic and Reconstructive Surgery, Division of Plastic Surgery, University of Alabama at Birmingham and Kirklin Clinics
James Neal Long, MD is a member of the following medical societies: Alpha Omega Alpha, American College of Surgeons, American Medical Association, American Society of Plastic Surgeons, Plastic Surgery Research Council, Sigma Xi, Southeastern Society of Plastic and Reconstructive Surgeons, and Southeastern Surgical Congress
Disclosure: Nothing to disclose.
Pankaj Tiwari, MD, Assistant Professor, Division of Plastic Surgery, Ohio State University
Disclosure: Nothing to disclose.
Francisco Talavera, PharmD, PhD, Senior Pharmacy Editor, eMedicine
Disclosure: Nothing to disclose.
Nicolas (Nick) G Slenkovich, MD, Director, Colorado Plastic Surgery Center
Nicolas (Nick) G Slenkovich, MD is a member of the following medical societies: American Academy of Otolaryngology-Head and Neck Surgery, American College of Surgeons, American Medical Association, American Society of Aesthetic Plastic Surgery, American Society of Plastic Surgeons, and Colorado Medical Society
Disclosure: Nothing to disclose.
Steven F Morris, MD, MSc, FRCSC, Professor, Department of Surgery, Professor, Department of Anatomy and Neurobiology, Cross Appointment (Professor), Division of Otolaryngology, Member, Faculty of Graduate Studies, Dalhousie University; Attending Plastic Surgeon, Queen Elizabeth II Health Sciences Center and Izaak Walton Killam Grace Health Centre, Nova Scotia
Disclosure: Nothing to disclose.