Venous Malformations Workup
- Author: Silvio Podda, MD; Chief Editor: Gregory Caputy, MD, PhD, FICS more...
Laboratory Studies
- Typically, no laboratory tests are indicated for cutaneous venous malformations. Clotting studies and CBC may be indicated in an occasional visceral lesion that is bleeding. If a particular anomaly is a diagnostic dilemma, urinary bFGF rarely may be indicated as part of the workup.
- A 2005 study was able to differentiate between proliferating hemangiomas and vascular malformations based on serum vascular endothelial growth factor (VEGF) levels.[1]
- Perform a coagulation profile on children with extensive disease, as there is a risk for low-grade, localized intravascular coagulopathy (LIC). Disseminated intravascular coagulopathy (DIC) is rare.
Imaging Studies
- Plain radiographs - Phleboliths pathognomonic
- MRI
- Most informative modality
- Hyperintense on T2-weighted images
- No flow voids
- Inhomogeneous contrast enhancement (like CT)
- CT scan
- Inhomogeneous contrast enhancement (like MRI)
- Phleboliths easily seen
- Ultrasound - Hypoechogenic, septated mass
Diagnostic Procedures
- Arteriography has little or no role in venous malformation unless the diagnosis is unclear.
Histologic Findings
- If the diagnosis is in doubt, biopsy the lesion!
- Most venous malformations are diagnosed based on a good history and physical examination; all of the above studies are ancillary.
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