Right Ventricular Infarction Differential Diagnoses

  • Author: Claudia Dima, MD; Chief Editor: Eric H Yang, MD   more...
 
Updated: Mar 29, 2011
 
 

Diagnostic Considerations

Although right ventricular infarction occurs in more than 30% of patients with inferior posterior left ventricular myocardial infarction, hemodynamically significant right ventricular infarction occurs in less than 10% of these patients.[3, 18, 19]

A right ventricular infarct should be considered in all patients who present with an acute inferior wall myocardial infarction, especially in the setting of a low cardiac output.

Should a patient with right ventricular infarction experience unexplained hypoxia despite administration of 100% oxygen, right-to-left shunting at the atrial level in the presence of right ventricular failure and increased right atrial pressure must be considered.[22, 23]

Differential Diagnoses

Proceed to Workup
 
 
Contributor Information and Disclosures
Author

Claudia Dima, MD  Fellow in Interventional Cardiology, Department of Cardiology, Banner Good Samaritan Medical Center

Disclosure: Nothing to disclose.

Coauthor(s)

David L Coven, MD, PhD  Assistant Professor of Medicine, Columbia University College of Physicians and Surgeons; Attending Physician in Interventional Cardiology, St Luke's-Roosevelt Hospital Center

David L Coven, MD, PhD is a member of the following medical societies: American College of Physicians, American Medical Association, and Massachusetts Medical Society

Disclosure: Nothing to disclose.

Kenneth B Desser, MD  Clinical Professor, Director of Cardiology Fellowship, Banner Good Samaritan Medical Center, Phoenix, Arizona

Disclosure: Nothing to disclose.

Ashish Pershad, MD  Consulting Staff, Heart and Vascular Center of Arizona

Ashish Pershad, MD is a member of the following medical societies: American College of Cardiology

Disclosure: Nothing to disclose.

Specialty Editor Board

George A Stouffer III, MD  Henry A Foscue Distinguished Professor of Medicine and Cardiology, Director of Interventional Cardiology, Cardiac Catheterization Laboratory, Chief of Clinical Cardiology, Division of Cardiology, University of North Carolina Medical Center

George A Stouffer III, MD is a member of the following medical societies: Alpha Omega Alpha, American College of Cardiology, American College of Physicians, American Heart Association, Phi Beta Kappa, and Society for Cardiac Angiography and Interventions

Disclosure: Nothing to disclose.

Francisco Talavera, PharmD, PhD  Adjunct Assistant Professor, University of Nebraska Medical Center College of Pharmacy; Editor-in-Chief, Medscape Drug Reference

Disclosure: Medscape Salary Employment

Chief Editor

Eric H Yang, MD  Associate Professor of Medicine, Director of Interventional Cardiology Fellowship Program, Henry Ford Hospital

Eric H Yang, MD is a member of the following medical societies: Alpha Omega Alpha

Disclosure: Nothing to disclose.

Additional Contributors

The authors and editors of eMedicine gratefully acknowledge the contributions of previous author Rex C Liu, MD, to the development and writing of the source article.

References
  1. Chockalingam A, Gnanavelu G, Subramaniam T, Dorairajan S, Chockalingam V. Right ventricular myocardial infarction: presentation and acute outcomes. Angiology. Jul-Aug 2005;56(4):371-6. [Medline].

  2. Forman MB, Goodin J, Phelan B, Kopelman H, Virmani R. Electrocardiographic changes associated with isolated right ventricular infarction. J Am Coll Cardiol. Sep 1984;4(3):640-3. [Medline].

  3. Garty I, Barzilay J, Bloch L, Antonelli D, Koltun B. The diagnosis and early complications of right ventricular infarction. Eur J Nucl Med. 1984;9(10):453-60. [Medline].

  4. Giannitsis E, Potratz J, Wiegand U, Stierle U, Djonlagic H, Sheikhzadeh A. Impact of early accelerated dose tissue plasminogen activator on in-hospital patency of the infarcted vessel in patients with acute right ventricular infarction. Heart. Jun 1997;77(6):512-6. [Medline]. [Full Text].

  5. Haupt HM, Hutchins GM, Moore GW. Right ventricular infarction: role of the moderator band artery in determining infarct size. Circulation. Jun 1983;67(6):1268-72. [Medline].

  6. Hirsowitz GS, Lakier JB, Goldstein S. Right ventricular function evaluated by radionuclide angiography in acute myocardial infarction. Am Heart J. Oct 1984;108(4 Pt 1):949-54. [Medline].

  7. Hurst JW. Comments about the electrocardiographic signs of right ventricular infarction. Clin Cardiol. Apr 1998;21(4):289-91. [Medline].

  8. Iqbal MZ, Liebson PR. Counterpulsation and dobutamine. Their use in treatment of cardiogenic shock due to right ventricular infarct. Arch Intern Med. Feb 1981;141(2):247-9. [Medline].

  9. Kinn JW, Ajluni SC, Samyn JG, Bates ER, Grines CL, O'Neill W. Rapid hemodynamic improvement after reperfusion during right ventricular infarction. J Am Coll Cardiol. Nov 1 1995;26(5):1230-4. [Medline].

  10. Bates ER. Revisiting reperfusion therapy in inferior myocardial infarction. J Am Coll Cardiol. Aug 1997;30(2):334-42. [Medline].

  11. Andersen HR, Nielsen D, Falk E. Right ventricular infarction: larger enzyme release with posterior than with anterior involvement. Int J Cardiol. Mar 1989;22(3):347-55. [Medline].

  12. Andersen HR, Falk E, Nielsen D. Right ventricular infarction: frequency, size and topography in coronary heart disease: a prospective study comprising 107 consecutive autopsies from a coronary care unit. J Am Coll Cardiol. Dec 1987;10(6):1223-32. [Medline].

  13. Andersen HR, Nielsen D, Lund O, Falk E. Prognostic significance of right ventricular infarction diagnosed by ST elevation in right chest leads V3R to V7R. Int J Cardiol. Jun 1989;23(3):349-56. [Medline].

  14. Birnbaum Y, Wagner GS, Barbash GI, Gates K, Criger DA, Sclarovsky S, et al. Correlation of angiographic findings and right (V1 to V3) versus left (V4 to V6) precordial ST-segment depression in inferior wall acute myocardial infarction. Am J Cardiol. Jan 15 1999;83(2):143-8. [Medline].

  15. Braat SH, Brugada P, den Dulk K, van Ommen V, Wellens HJ. Value of lead V4R for recognition of the infarct coronary artery in acute inferior myocardial infarction. Am J Cardiol. Jun 1 1984;53(11):1538-41. [Medline].

  16. Braat SH, Brugada P, de Zwaan C, Coenegracht JM, Wellens HJ. Value of electrocardiogram in diagnosing right ventricular involvement in patients with an acute inferior wall myocardial infarction. Br Heart J. Apr 1983;49(4):368-72. [Medline]. [Full Text].

  17. Elkayam U, Halprin SL, Frishman W, Strom J, Cohen MN. Echocardiographic findings in cardiogenic shock due to right ventricular myocardial infarction. Cathet Cardiovasc Diagn. 1979;5(3):289-94. [Medline].

  18. Lisbona R, Sniderman A, Derbekyan V, Lande I, Boudreau R. Phase and amplitude imaging in the diagnosis of acute right ventricular damage in inferior infarction. Clin Nucl Med. Nov 1983;8(11):517-20. [Medline].

  19. Martin W, Tweddel A, McGhie I, Hutton I. The evaluation of right ventricular function in acute myocardial infarction by xenon-133. Nucl Med Commun. Jan 1989;10(1):35-43. [Medline].

  20. Mittal SR. Isolated right ventricular infarction. Int J Cardiol. Aug 1994;46(1):53-60. [Medline].

  21. Silverman BD, Carabajal NR, Chorches MA, Taranto AI. Tricuspid regurgitation and acute myocardial infarction. Arch Intern Med. Jul 1982;142(7):1394-5. [Medline].

  22. Nader DA, Ceretto WJ, Vieweg WV. Atrial pacing in the management of right ventricular infarction. South Med J. Mar 1981;74(3):362-3. [Medline].

  23. Pfisterer M, Emmenegger H, Müller-Brand J, Burkart F. Prevalence and extent of right ventricular dysfunction after myocardial infarction--relation to location and extent of infarction and left ventricular function. Int J Cardiol. Sep 1990;28(3):325-32. [Medline].

  24. Sugimoto T, Ogawa K, Asada T, Mukohara N, Higami T, Obo H, et al. Surgical treatment of ventricular septal perforation with right ventricular infarction. J Cardiovasc Surg (Torino). Feb 1996;37(1):71-4. [Medline].

  25. Mavric Z, Zaputovic L, Matana A, Kucic J, Roje J, Marinovic D, et al. Prognostic significance of complete atrioventricular block in patients with acute inferior myocardial infarction with and without right ventricular involvement. Am Heart J. Apr 1990;119(4):823-8. [Medline].

  26. Singhal AM, Ilangovan S, Mehta S, Portaluppi F. Isolated right ventricular infarction followed by posterior left ventricular infarction after a few days. Acta Cardiol. 1984;39(4):307-12. [Medline].

  27. Strauss HD, Sobel BE, Roberts R. The influence of occult right ventricular infarction on enzymatically estimated infarct size, hemodynamics and prognosis. Circulation. Sep 1980;62(3):503-8. [Medline].

  28. Dokainish H, Abbey H, Gin K, Ramanathan K, Lee PK, Jue J. Usefulness of tissue Doppler imaging in the diagnosis and prognosis of acute right ventricular infarction with inferior wall acute left ventricular infarction. Am J Cardiol. May 1 2005;95(9):1039-42. [Medline].

  29. Chockalingam A, Gnanavelu G, Alagesan R, Subramaniam T. Myocardial performance index in evaluation of acute right ventricular myocardial infarction. Echocardiography. Aug 2004;21(6):487-94. [Medline].

  30. Lahm T, McCaslin CA, Wozniak TC, Ghumman W, Fadl YY, Obeidat OS, et al. Medical and surgical treatment of acute right ventricular failure. J Am Coll Cardiol. Oct 26 2010;56(18):1435-46. [Medline].

  31. Robalino BD, Petrella RW, Jubran FY, Bravo EL, Healy BP, Whitlow PL. Atrial natriuretic factor in patients with right ventricular infarction. J Am Coll Cardiol. Mar 1 1990;15(3):546-53. [Medline].

  32. Roth A, Miller HI, Kaluski E, Keren G, Shargorodsky B, Krakover R, et al. Early thrombolytic therapy does not enhance the recovery of the right ventricle in patients with acute inferior myocardial infarction and predominant right ventricular involvement. Cardiology. 1990;77(1):40-9. [Medline].

  33. Schuler G, Hofmann M, Schwarz F, Mehmel H, Manthey J, Tillmanns H, et al. Effect of successful thrombolytic therapy on right ventricular function in acute inferior wall myocardial infarction. Am J Cardiol. Nov 1 1984;54(8):951-7. [Medline].

  34. Sharpe DN, Botvinick EH, Shames DM, Schiller NB, Massie BM, Chatterjee K, et al. The noninvasive diagnosis of right ventricular infarction. Circulation. Mar 1978;57(3):483-90. [Medline].

  35. Zorio E, Arnau MA, Rueda J, Almenar L, Osa A, Martínez-Dolz L, et al. The presence of epsilon waves in a patient with acute right ventricular infarction. Pacing Clin Electrophysiol. Mar 2005;28(3):245-7. [Medline].

  36. Sugiura T, Iwasaka T, Shiomi K, Nagahama Y, Takehana K, Inada M. Clinical significance of right ventricular dilatation in patients with right ventricular infarction. Coron Artery Dis. Dec 1994;5(12):955-9. [Medline].

  37. Tan HC, Yeo TC, Lim YT, Chia BL. A case of unusual electrocardiographic presentation of right ventricular myocardial infarction. Ann Acad Med Singapore. Nov 1997;26(6):844-7. [Medline].

  38. Reynolds HR, Hochman JS. Cardiogenic shock: current concepts and improving outcomes. Circulation. Feb 5 2008;117(5):686-97. [Medline].

  39. Tobinick E, Schelbert HR, Henning H, LeWinter M, Taylor A, Ashburn WL, et al. Right ventricular ejection fraction in patients with acute anterior and inferior myocardial infarction assessed by radionuclide angiography. Circulation. Jun 1978;57(6):1078-84. [Medline].

  40. Vesterby A, Steen M. Isolated right ventricular myocardial infarction. A case report. Acta Med Scand. 1984;216(2):233-5. [Medline].

  41. Yoshino H, Udagawa H, Shimizu H, Kachi E, Kajiwara T, Yano K, et al. ST-segment elevation in right precordial leads implies depressed right ventricular function after acute inferior myocardial infarction. Am Heart J. Apr 1998;135(4):689-95. [Medline].

  42. Zeymer U, Neuhaus KL, Wegscheider K, Tebbe U, Molhoek P, Schröder R. Effects of thrombolytic therapy in acute inferior myocardial infarction with or without right ventricular involvement. HIT-4 Trial Group. Hirudin for Improvement of Thrombolysis. J Am Coll Cardiol. Oct 1998;32(4):876-81. [Medline].

  43. Inglessis I, Shin JT, Lepore JJ, Palacios IF, Zapol WM, Bloch KD, et al. Hemodynamic effects of inhaled nitric oxide in right ventricular myocardial infarction and cardiogenic shock. J Am Coll Cardiol. Aug 18 2004;44(4):793-8. [Medline].

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Table. Sensitivity and Specificity of More Than 1 mm of ST-Segment Elevation in V1, V3 R, and V4 R
Leads Sensitivity (%) Specificity (%)
V12892
V3 R6997
V4 R9395
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