Further Inpatient Care
Admit the patient for testing and surgical intervention.
Further Outpatient Care
- Monitor patients annually with echocardiography to detect the occurrence of new cardiac myxomas.
- Annual history and physical examination also is required to detect the development of extracardiac myxomas, other tumors, and signs and symptoms of endocrine dysfunction.
Inpatient & Outpatient Medications
- No specific medications are indicated for this condition.
- Antibiotic prophylaxis is required if an associated valvular insufficiency exists.
- Medical management of endocrine dysfunction may be appropriate.
Transfer
Transfer of the patient may be required for further diagnostic evaluation and surgical intervention.
Deterrence/Prevention
No particular deterrent is available.
Complications
- Recurrent myxoma growth
- Congestive heart failure
- Stroke
- Peripheral embolization including coronary, retinal, renal, celiac, and femoral and pulmonary arteries
- Arrhythmia
- Pulmonary hypertension
Prognosis
Prognosis generally is good and depends on the proclivity of cardiac myxomas to recur. The risks associated with open-heart surgery increase with each successive surgery.
Patient Education
The family should be aware that this is an autosomal dominant disorder with a 50% chance that the offspring of an affected individual will have the disorder.
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Casey M, Mah C, Merliss AD, et al. Identification of a novel genetic locus for familial cardiac myxomas and Carney complex. Circulation. Dec 8 1998;98(23):2560-6. [Medline].
Casey M, Vaughan CJ, He J, et al. Mutations in the protein kinase A R1alpha regulatory subunit cause familial cardiac myxomas and Carney complex. J Clin Invest. Sep 2000;106(5):R31-8. [Medline].
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