Multiple Minute Digitate Hyperkeratoses Follow-up
- Author: Annie Wester, MS; Chief Editor: Dirk M Elston, MD more...
Further Outpatient Care
Regular annual follow-up examinations are recommended.
Further Inpatient Care
Follow patients on a yearly basis because of the rarity of minute digitate hyperkeratosis (MMDH) (spiny hyperkeratosis). In particular, an annual skin examination and follow up by a primary care physician for age-appropriate screenings are recommended.
No reports in the evidence-based literature have examined the prognosis of minute digitate hyperkeratosis (spiny hyperkeratosis). However, the lesions themselves are believed to be benign in nature.
The larger unanswered question is the role of associated findings that may occur with minute digitate hyperkeratosis (spiny hyperkeratosis). Currently, multiple minute digitate hyperkeratosis appears to be found inconsistently with other disease processes. Any further associations would require a larger series of patients or pathogenic, molecular, or genetic studies to correlate the somewhat random findings noted to date. Anecdotal and clinical observations have suggested early-onset/congenital multiple minute digitate hyperkeratosis (spiny hyperkeratosis) differs from late-onset/acquired forms. Although not backed by a large body of evidence, the late-onset multiple minute digitate hyperkeratosis (spiny hyperkeratosis) is presumed to have an increased association with inflammatory or malignant disease in some cases. However, the evidence for these associations is anecdotal.[6, 16]
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