Lactic Acidosis Differential Diagnoses

  • Author: Kyle J Gunnerson, MD; Chief Editor: Michael R Pinsky, MD, CM, FCCP, FCCM   more...
 
Updated: Jun 3, 2011
 
 

Diagnostic Considerations

Conditions to be considered in the diagnosis of lactic acidosis include the following:

  • Inborn errors of metabolism
  • Pyruvate dehydrogenase deficiency
  • Oxidative phosphorylation defects
  • Cardiogenic shock
  • Cardiogenic pulmonary edema
  • Pyruvate carboxylase deficiency
  • Glucose-6-phosphatase deficiency

Differential Diagnoses

Proceed to Workup
 
 
Contributor Information and Disclosures
Author

Kyle J Gunnerson, MD  Associate Professor, Departments of Anesthesiology/CCM and Emergency Medicine, Virginia Commonwealth University School of Medicine; Associate Director, Center for Adult Critical Care, Chief, Division of Critical Care, Director of Critical Care Anesthesiology, Co-Director of Cardiac Surgery ICU, Departments of Anesthesiology and Emergency Medicine, Virginia Commonwealth University Health System

Kyle J Gunnerson, MD is a member of the following medical societies: American Academy of Emergency Medicine, American College of Chest Physicians, American College of Emergency Physicians, American College of Physicians, American Medical Association, Society for Academic Emergency Medicine, and Society of Critical Care Medicine

Disclosure: Nothing to disclose.

Specialty Editor Board

Cory Franklin, MD  Professor, Department of Medicine, Rosalind Franklin University of Medicine and Science; Director, Division of Critical Care Medicine, Cook County Hospital

Cory Franklin, MD is a member of the following medical societies: New York Academy of Sciences and Society of Critical Care Medicine

Disclosure: Nothing to disclose.

Francisco Talavera, PharmD, PhD  Adjunct Assistant Professor, University of Nebraska Medical Center College of Pharmacy; Editor-in-Chief, Medscape Drug Reference

Disclosure: Medscape Salary Employment

Chief Editor

Michael R Pinsky, MD, CM, FCCP, FCCM  Professor of Critical Care Medicine, Bioengineering, Cardiovascular Disease and Anesthesiology, Vice-Chair of Academic Affairs, Department of Critical Care Medicine, University of Pittsburgh School of Medicine, University of Pittsburgh Medical Center

Michael R Pinsky, MD, CM, FCCP, FCCM is a member of the following medical societies: American College of Chest Physicians, American College of Critical Care Medicine, American Heart Association, American Thoracic Society, Association of University Anesthetists, European Society of Intensive Care Medicine, Shock Society, and Society of Critical Care Medicine

Disclosure: LiDCO Ltd Honoraria Consulting; iNTELOMED Intellectual property rights Board membership; Edwards Lifesciences Honoraria Consulting; Applied Physiology, Ltd Honoraria Consulting; Cheetah Medical Consulting fee Consulting

Additional Contributors

The authors and editors of eMedicine gratefully acknowledge the contributions of previous author Sat Sharma, MD, FRCPC,to the development and writing of the source article.

References

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Pathophysiologic classification of lactic acidosis.
 
 
 
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