eMedicine Specialties > Gastroenterology > Esophagus
Boerhaave Syndrome: Follow-up
Updated: Aug 12, 2008
Follow-up
Complications
- Esophageal rupture may lead to the development of septicemia, pneumomediastinum, mediastinitis, massive pleural effusion, empyema, pneumomediastinum, or subcutaneous emphysema.
- If the esophageal rupture extends directly into the pleura, hydropneumothorax is expected.
- In adults, this occurs more commonly on the left side of the pleura.
- In neonates, the esophageal rupture usually occurs on the right side.
- After the esophageal rupture, free air enters the mediastinum and also may spread to the adjacent structures and result in mediastinal abscess or superimposed secondary infection.
- Other complications include acute respiratory distress syndrome, pneumomediastinum, pneumothorax, and hydrothorax.
Prognosis
- Prognosis is directly contingent on early recognition and appropriate intervention.
- Early diagnosis of Boerhaave syndrome allows prompt surgical repair.
- Diagnosis and surgery within 24 hours carry a 75% survival rate. This drops to approximately 50% after a 24-hour delay and approximately 10% after 48 hours.
Miscellaneous
Medicolegal Pitfalls
- Failure to diagnose
The authors and editors of eMedicine gratefully acknowledge the contributions of previous coauthor, Prakash Ramanathan, MD, to the development and writing of this article.
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References
Kish GF, Katske FA. A case of recurrent Boerhaave's syndrome. W V Med J. Feb 1980;76(2):27-30. [Medline].
Bladergroen MR, Lowe JE, Postlethwait RW. Diagnosis and recommended management of esophageal perforation and rupture. Ann Thorac Surg. Sep 1986;42(3):235-9. [Medline].
Adam A, Watkinson AF, Dussek J. Boerhaave syndrome: to treat or not to treat by means of insertion of a metallic stent. J Vasc Interv Radiol. Sep-Oct 1995;6(5):741-3; discussion 744-6. [Medline].
Adams BD, Sebastian BM, Carter J. Honoring the Admiral: Boerhaave-van Wassenaer's syndrome. Dis Esophagus. 2006;19(3):146-51. [Medline].
Bjerke HS. Boerhaave's syndrome and barogenic injuries of the esophagus. Chest Surg Clin N Am. Nov 1994;4(4):819-25. [Medline].
Bonheim N, Alavi I. Boerhaave's syndrome: spontaneous rupture of the esophagus. Chic Med Sch Q. 1970;29(1):31-6. [Medline].
Chiu CL, Gambach RR. Spontaneous perforation of the esophagus (Boerhaave's syndrome). J Iowa Med Soc. Sep 1973;63(9):436-8. [Medline].
Clark W, Cook IJ. Spontaneous intramural haematoma of the oesophagus: radiologic recognition. Australas Radiol. Aug 1996;40(3):269-72. [Medline].
Craven GG, Whittaker MG. Boerhaave's syndrome as a complication of pre-existent gastrointestinal disease. Ir J Med Sci. Dec 1992;161(12):670-4. [Medline].
Crookes PF. RE: Hermann Boerhaave: the man behind the syndrome. Dis Esophagus. Oct 1997;10(4):303. [Medline].
Curtis DL, Burbige EJ, Milligan FD. Boerhaave's syndrome: role of esophagoscopy. Gastrointest Endosc. May 1976;22(4):208-9. [Medline].
Datta CK, Brannon JV. Spontaneous rupture of esophagus (Boerhaave syndrome): a review of literature and a case presentation. W V Med J. Jul 1979;75(7):180-2. [Medline].
Davies AP, Vaughan R. Expanding mesh stent in the emergency treatment of Boerhaave's syndrome. Ann Thorac Surg. May 1999;67(5):1482-3. [Medline].
Davis R. The Boerhaave syndrome associated with carcinoma of the oesophagus. S Afr Med J. Dec 1 1973;47(47):2269-72. [Medline].
Drury M, Anderson W, Heffner JE. Diagnostic value of pleural fluid cytology in occult Boerhaave's syndrome. Chest. Sep 1992;102(3):976-8. [Medline].
Duehring GL. Boerhaave syndrome. Radiol Technol. Sep-Oct 2000;72(1):51-5. [Medline].
Dumonceau JM, Deviere J, Cappello M, et al. Endoscopic treatment of Boerhaave's syndrome. Gastrointest Endosc. Oct 1996;44(4):477-9. [Medline].
Eubanks PJ, Hu E, Nguyen D, Procaccino F, et al. Case of Boerhaave's syndrome successfully treated with a self-expandable metallic stent. Gastrointest Endosc. Jun 1999;49(6):780-3. [Medline].
Ghassemi KF, Rodriguez HJ, Vesga L, et al. Endoscopic treatment of Boerhaave syndrome using a removable self-expandable plastic stent. J Clin Gastroenterol. Oct 2007;41(9):863-4. [Medline].
Hansen CP, Bertelsen S. Boerhaave's syndrome: spontaneous rupture of the oesophagus. Ann Chir Gynaecol. 1988;77(4):138-41. [Medline].
Henderson JA, Peloquin AJ. Boerhaave revisited: spontaneous esophageal perforation as a diagnostic masquerader. Am J Med. May 1989;86(5):559-67. [Medline].
Jagminas L, Silverman RA. Boerhaave's syndrome presenting with abdominal pain and right hydropneumothorax. Am J Emerg Med. Jan 1996;14(1):53-6. [Medline].
Janjua KJ. Boerhaave's syndrome. Postgrad Med J. May 1997;73(859):265-70. [Medline].
Jenkins IR, Raymond R. Boerhaave's syndrome complicated by a large bronchopleural fistula. Chest. Mar 1994;105(3):964-5. [Medline].
John BE, Zua MS. Boerhaave's syndrome--an elusive diagnosis. Tenn Med. Feb 1997;90(2):56-8. [Medline].
Kallis P, Belsham PA, Pepper JR. Spontaneous rupture of the oesophagus (Boerhaave's syndrome): conservative versus surgical management. J R Soc Med. Nov 1991;84(11):690-1. [Medline].
Klausner JM, Epstein L, Peer G, et al. Perforation of the esophagus (Boerhaave's syndrome) during hemodialysis. Nephron. 1985;40(3):372-3. [Medline].
Klin B, Berlatzky Y, Uretzky G. Boerhaave's syndrome: case report and review of the literature. Isr J Med Sci. Feb 1989;25(2):113-5. [Medline].
Korn O, Onate JC, Lopez R. Anatomy of the Boerhaave syndrome. Surgery. Feb 2007;141(2):222-8. [Medline].
Kyriacou DN. A case of Boerhaave's syndrome presenting as diffuse left pulmonary infiltrate. Ann Emerg Med. Nov 1991;20(11):1239-42. [Medline].
Lawrence DR, Ohri SK, et al. Primary esophageal repair for Boerhaave's syndrome. Ann Thorac Surg. 1999;67(3):818-20. [Medline].
Levinsky L, Adler RH. Recurrent diagphragmatic herniation: following gastric onlay reinforcement of esophageal rupture (Boerhaave syndrome). N Y State J Med. Feb 1980;80(2):244-8. [Medline].
Levy F, Mysko WK, Kelen GD. Spontaneous esophageal perforation presenting with right-sided pleural effusion. J Emerg Med. May-Jun 1995;13(3):321-5. [Medline].
Lin WC, Chen JD, Tiu CM, et al. Boerhaave syndrome with atypical clinical presentations diagnosed by computed tomography. Zhonghua Yi Xue Za Zhi (Taipei). Jan 2002;65(1):45-8. [Medline].
Lujan HJ, Lin PH, Boghossian SP, et al. Recurrent spontaneous rupture of the esophagus: an unusual late complication of Boerhaave's syndrome. Surgery. Sep 1997;122(3):634-6. [Medline].
Marshall WB. Boerhaave syndrome: a case report. AANA J. Aug 2002;70(4):289-92. [Medline].
McCartney J, Dobrow J, Hendrix TR. Boerhaave syndrome. Johns Hopkins Med J. Jan 1979;144(1):28-33. [Medline].
Meyer GW, Castell DO. Evaluation and management of diseases of the esophagus. Am J Otolaryngol. Nov 1981;2(4):336-44. [Medline].
Michel L. Post-emetic laceration and rupture of the gastroesophageal junction. Acta Chir Belg. Jan-Feb 1982;82(1):13-24. [Medline].
Munemura T, Suzuki O, Ootake S, et al. A rare case of spontaneous esophageal rupture (Boerhaave's syndrome) associated with pulmonary rupture. Jpn J Thorac Cardiovasc Surg. Nov 1998;46(11):1074-7. [Medline].
Pezzulli FA, Aronson D, Goldberg N. Computed tomography of mediastinal hematoma secondary to unusual esophageal laceration: a Boerhaave variant. J Comput Assist Tomogr. Jan-Feb 1989;13(1):129-31. [Medline].
Phillips LG Jr, Cogbill CL, Makkar JC, et al. Barogenic rupture of the esophagus (Boerhaave's syndrome): successful treatment of a late case. Am Surg. Aug 1982;48(8):430-4. [Medline].
Rogers LF, Puig AW, Dooley BN, et al. Diagnostic considerations in mediastinal emphysema: a pathophysiologic-roentgenologic approach to Boerhaave's syndrome and spontaneous pneumomediastinum. Am J Roentgenol Radium Ther Nucl Med. Jul 1972;115(3):495-511. [Medline].
Rozycki GS. Image of the month. Esophageal perforation (Boerhaave syndrome). Arch Surg. Mar 2001;136(3):355-6. [Medline].
Sabanathan S, Eng J, Richardson J. Surgical management of intrathoracic oesophageal rupture. Br J Surg. Jun 1994;81(6):863-5. [Medline].
Sakamoto Y, Tanaka N, Furuya T, et al. Surgical management of late esophageal perforation. Thorac Cardiovasc Surg. Dec 1997;45(6):269-72. [Medline].
Salim AS. Jejunostomy feeding for the conservative management of spontaneous rupture of the oesophagus. Br J Clin Pract. Spring 1991;45(1):37-40. [Medline].
Salo JA, Seppala KM, Pitkaranta PP, et al. Spontaneous rupture and functional state of the esophagus. Surgery. Nov 1992;112(5):897-900. [Medline].
Scott HJ, Rosin RD. Thoracoscopic repair of a transmural rupture of the oesophagus (Boerhaave's syndrome). J R Soc Med. Jul 1995;88(7):414P-415P. [Medline].
Singh GS, Slovis CM. "Occult" Boerhaave's syndrome. J Emerg Med. Jan-Feb 1988;6(1):13-6. [Medline].
Smyth AR, Wastell C. Spontaneous rupture of the oesophagus (Boerhaave's syndrome): delayed diagnosis and successful conservative management. J R Soc Med. Aug 1989;82(8):498. [Medline].
Troum S, Lane CE, Dalton ML Jr. Surviving Boerhaave's syndrome without thoracotomy. Chest. Jul 1994;106(1):297-9. [Medline].
Van Nooten G, Azagra JS, Alle JL, et al. Spontaneous rupture of the esophagus after coronary artery bypass. Acta Chir Belg. Nov-Dec 1987;87(6):367-70. [Medline].
Weil RJ. Candidal mediastinitis after surgical repair of esophageal perforation. South Med J. Aug 1991;84(8):1052-3. [Medline].
White RK, Morris DM. Diagnosis and management of esophageal perforations. Am Surg. Feb 1992;58(2):112-9. [Medline].
Zawisza MJ, Geisler A. Spontaneous rupture of esophagus (Boerhaave's syndrome): case report and literature review. J Am Osteopath Assoc. Jun 1988;88(6):787-90. [Medline].
Zisis C, Guillin A, Heyries L, et al. Stent placement in the management of oesophageal leaks. Eur J Cardiothorac Surg. Mar 2008;33(3):451-6. [Medline].
Further Reading
Keywords
Boerhaave syndrome, Boerhaave's syndrome, esophageal perforation, esophageal rupture, perforated esophagus, esophagus perforation, esophagus rupture, ruptured esophagus, esophagus tear, esophageal tear, spontaneous esophageal rupture, spontaneous rupture of the esophagus, transmural perforation of the esophagus, forceful emesis, emesis complications
Follow-up: Boerhaave Syndrome