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Portal-Systemic Encephalopathy Follow-up

  • Author: Gagan K Sood, MD; Chief Editor: BS Anand, MD  more...
Updated: Dec 18, 2014

Further Inpatient Care

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  • Alcohol rehabilitation is a requirement for consideration of acceptance for listing for orthotopic liver transplantation. Regardless of whether the patient is a candidate for orthotopic liver transplantation, the development of portosystemic encephalopathy is a potential revelation that permits progress toward achieving and maintaining abstinence. This is a critical step for increasing the probability of survival and often is best approached initially by taking advantage of the inpatient status.


See the list below:

  • Respiratory and ventilatory insufficiency and failure to protect the airway with consequent aspiration are anticipated complications that should be avoided with endotracheal intubation.


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  • In general, the prognosis for patients with advanced liver disease is poor unless they are able to undergo liver transplantation. The contribution that portosystemic encephalopathy makes to the decline of these individuals is limited, and, rather than acting as a causal factor, it is essentially a marker of decompensated liver disease. As with other complications of chronic liver disease, survival likely correlates better with Child-Pugh score than the outcome of the complication itself.
Contributor Information and Disclosures

Gagan K Sood, MD Associate Professor, Department of Medicine and Surgery, Baylor College of Medicine

Gagan K Sood, MD is a member of the following medical societies: American Association for the Study of Liver Diseases, American Gastroenterological Association

Disclosure: Nothing to disclose.

Specialty Editor Board

Francisco Talavera, PharmD, PhD Adjunct Assistant Professor, University of Nebraska Medical Center College of Pharmacy; Editor-in-Chief, Medscape Drug Reference

Disclosure: Received salary from Medscape for employment. for: Medscape.

Noel Williams, MD, FRCPC FACP, MACG, Professor Emeritus, Department of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada; Professor, Department of Internal Medicine, Division of Gastroenterology, University of Alberta, Edmonton, Alberta, Canada

Noel Williams, MD, FRCPC is a member of the following medical societies: Royal College of Physicians and Surgeons of Canada

Disclosure: Nothing to disclose.

Chief Editor

BS Anand, MD Professor, Department of Internal Medicine, Division of Gastroenterology, Baylor College of Medicine

BS Anand, MD is a member of the following medical societies: American Association for the Study of Liver Diseases, American College of Gastroenterology, American Gastroenterological Association, American Society for Gastrointestinal Endoscopy

Disclosure: Nothing to disclose.

Additional Contributors

Ann Ouyang, MBBS Professor, Department of Internal Medicine, Pennsylvania State University College of Medicine; Attending Physician, Division of Gastroenterology and Hepatology, Milton S Hershey Medical Center

Disclosure: Nothing to disclose.


The authors and editors of Medscape Reference gratefully acknowledge the contributions of previous coauthor, Blake A Jones, MD, to the development and writing of this article.

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