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Schatzki Ring Medication

  • Author: Rajeev Vasudeva, MD; Chief Editor: Julian Katz, MD  more...
 
Updated: Dec 16, 2014
 

Medication Summary

No specific drug therapy for Schatzki ring exists. Consider treating any associated reflux disease with potent antisecretory agents (eg, proton pump inhibitors).

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Proton pump inhibitors

Class Summary

Inhibits H+/K+ -ATPase enzyme system in the gastric parietal cells, resulting in decreased gastric acid secretion. Used for esophagitis or unresponsiveness to H2-antagonist therapy.

Rabeprazole sodium (Aciphex)

 

Decreases gastric acid secretion by inhibiting the parietal cell H+/K+ ATP pump. For short-term (4-8 wk) treatment and relief symptomatic erosive or ulcerative GERD. Patients not healed after 8 wk, consider additional 8-wk course.

Esomeprazole magnesium (Nexium)

 

S-isomer of omeprazole. Inhibits gastric acid secretion by inhibiting H+/K+ -ATPase enzyme system at secretory surface of gastric parietal cells.

Omeprazole (Prilosec)

 

Inhibits gastric acid secretion. Used for the short-term treatment (4-8 wk) of GERD. May be needed for long-term therapy.

Pantoprazole (Protonix)

 

Suppresses gastric acid secretion by specifically inhibiting H+/K+ ATPase enzyme system at the secretory surface of gastric parietal cells.

Lansoprazole (Prevacid)

 

Inhibits gastric acid secretion. Used for up to 8 wk to treat all grades of erosive esophagitis.

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Contributor Information and Disclosures
Author

Rajeev Vasudeva, MD Clinical Professor of Medicine, Consultants in Gastroenterology, University of South Carolina School of Medicine

Rajeev Vasudeva, MD is a member of the following medical societies: American College of Gastroenterology, Columbia Medical Society, South Carolina Gastroenterology Association, American Gastroenterological Association, American Society for Gastrointestinal Endoscopy, South Carolina Medical Association

Disclosure: Received honoraria from Pricara for speaking and teaching; Received consulting fee from UCB for consulting.

Specialty Editor Board

Francisco Talavera, PharmD, PhD Adjunct Assistant Professor, University of Nebraska Medical Center College of Pharmacy; Editor-in-Chief, Medscape Drug Reference

Disclosure: Received salary from Medscape for employment. for: Medscape.

Chief Editor

Julian Katz, MD Clinical Professor of Medicine, Drexel University College of Medicine

Julian Katz, MD is a member of the following medical societies: American College of Gastroenterology, American College of Physicians, American Gastroenterological Association, American Geriatrics Society, American Medical Association, American Society for Gastrointestinal Endoscopy, American Society of Law, Medicine & Ethics, American Trauma Society, Association of American Medical Colleges, Physicians for Social Responsibility

Disclosure: Nothing to disclose.

Acknowledgements

Mounzer Al Samman, MD Assistant Professor, Department of Internal Medicine, Division of Gastroenterology, Texas Tech University School of Medicine

Mounzer Al Al Samman, MD is a member of the following medical societies: American College of Gastroenterology, American College of Physicians, and American Gastroenterological Association

Disclosure: Nothing to disclose.

John Schaberg, MD

Disclosure: Nothing to disclose.

Noel Williams, MD Professor Emeritus, Department of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada; Professor, Department of Internal Medicine, Division of Gastroenterology, University of Alberta, Edmonton, Alberta, Canada

Noel Williams, MD is a member of the following medical societies: Royal College of Physicians and Surgeons of Canada

Disclosure: Nothing to disclose.

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Endoscopic appearance of the distal esophagus illustrating a Schatzki ring.
Barium swallow illustrating an indentation at the gastroesophageal junction consistent with a Schatzki ring above a sliding hiatal hernia.
A Schatzki ring dilated by the passage of a single large bougie.
 
 
 
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