Pancreatic Pseudocysts Clinical Presentation
- Author: Louis R Lambiase, MD, MHA; Chief Editor: Julian Katz, MD more...
History
- No specific set of symptoms is pathognomic of pseudocysts; however, consider the possibility of a pseudocyst in a patient who has persistent abdominal pain, anorexia, or abdominal mass after a case of pancreatitis.
- Rarely, patients present with jaundice or sepsis from an infected pseudocyst.
- Pleural effusion is also a common finding.
Physical
- The sensitivity of physical examination findings is limited.
- Patients very frequently have a tender abdomen.
- Patients occasionally have a palpable mass in the abdomen.
- Peritoneal signs suggest rupture of the cyst or infection.
- Other possible findings include the following:
- Fever
- Scleral icterus
- Pleural effusion
Causes
Acute or chronic pancreatitis or abdominal trauma causes pseudocysts. If no history of pancreatitis or trauma exists, the diagnosis must be carefully confirmed.
Jani N, Bani Hani M, Schulick RD, Hruban RH, Cunningham SC. Diagnosis and management of cystic lesions of the pancreas. Diagn Ther Endosc. 2011;2011:478913. [Medline]. [Full Text].
Brun A, Agarwal N, Pitchumoni CS. Fluid collections in and around the pancreas in acute pancreatitis. J Clin Gastroenterol. Aug 2011;45(7):614-25. [Medline].
Zheng M, Qin M. Endoscopic ultrasound guided transgastric stenting for the treatment of traumatic pancreatic pseudocyst. Hepatogastroenterology. Jul-Aug 2011;58(109):1106-9. [Medline].
Weckman L, Kylanpaa ML, Puolakkainen P, Halttunen J. Endoscopic treatment of pancreatic pseudocysts. Surg Endosc. Apr 2006;20(4):603-7. Epub 2006 Jan 19. [Medline].
Aljarabah M, Ammori BJ. Laparoscopic and endoscopic approaches for drainage of pancreatic pseudocysts: a systematic review of published series. Surg Endosc. Nov 2007;21(11):1936-44. [Medline].
Oida T, Mimatsu K, Kano H, Kawasaki A, Kuboi Y, Fukino N, et al. Laparoscopic Cystogastrostomy via the Posterior Approach for Pancreatic Pseudocyst Drainage. Hepatogastroenterology. Nov 14 2011;58(110-111):1771-1775. [Medline].
Beckingham IJ, Krige JE, Bornman PC, Terblanche J. Long term outcome of endoscopic drainage of pancreatic pseudocysts. Am J Gastroenterol. Jan 1999;94(1):71-4. [Medline].
Binmoeller KF, Seifert H, Walter A, Soehendra N. Transpapillary and transmural drainage of pancreatic pseudocysts. Gastrointest Endosc. Sep 1995;42(3):219-24. [Medline].
Criado E, De Stefano AA, Weiner TM, Jaques PF. Long term results of percutaneous catheter drainage of pancreatic pseudocysts. Surg Gynecol Obstet. Oct 1992;175(4):293-8. [Medline].
D'Agostino HB, vanSonnenberg E, Sanchez RB, Goodacre BW, Villaveiran RG, Lyche K. Treatment of pancreatic pseudocysts with percutaneous drainage and octreotide. Work in progress. Radiology. Jun 1993;187(3):685-8. [Medline].
El Hamel A, Parc R, Adda G, Bouteloup PY, Huguet C, Malafosse M. Bleeding pseudocysts and pseudoaneurysms in chronic pancreatitis. Br J Surg. Sep 1991;78(9):1059-63. [Medline].
Gershoni-Baruch R, Mandel H, Bar El H, Bar-Nizan N, Borochowitz Z, Dar H. Interstitial deletion (6)q13q15. Am J Med Genet. Apr 24 1996;62(4):345-7. [Medline].
Heider R, Meyer AA, Galanko JA, Behrns KE. Percutaneous drainage of pancreatic pseudocysts is associated with a higher failure rate than surgical treatment in unselected patients. Ann Surg. Jun 1999;229(6):781-7; discussion 787-9. [Medline].
Howell DA, Elton E, Parsons WG. Endoscopic management of pseudocysts of the pancreas. Gastrointest Endosc Clin N Am. Jan 1998;8(1):143-62. [Medline].
Lewandrowski KB, Southern JF, Pins MR, Compton CC, Warshaw AL. Cyst fluid analysis in the differential diagnosis of pancreatic cysts. A comparison of pseudocysts, serous cystadenomas, mucinous cystic neoplasms, and mucinous cystadenocarcinoma. Ann Surg. Jan 1993;217(1):41-7. [Medline].
Morton JM, Brown A, Galanko JA, Norton JA, Grimm IS, Behrns KE. A national comparison of surgical versus percutaneous drainage of pancreatic pseudocysts: 1997-2001. J Gastrointest Surg. Jan 2005;9(1):15-20; discussion 20-1. [Medline].
Nealon WH, Walser E. Surgical management of complications associated with percutaneous and/or endoscopic management of pseudocyst of the pancreas. Ann Surg. Jun 2005;241(6):948-57; discussion 957-60. [Medline].
Nguyen BL, Thompson JS, Edney JA, Bragg LE, Rikkers LF. Influence of the etiology of pancreatitis on the natural history of pancreatic pseudocysts. Am J Surg. Dec 1991;162(6):527-30; discussion 531. [Medline].
Pitchumoni CS, Agarwal N. Pancreatic pseudocysts. When and how should drainage be performed?. Gastroenterol Clin North Am. Sep 1999;28(3):615-39. [Medline].
Sahani DV, Kadavigere R, Saokar A, Fernandez-del Castillo C, Brugge WR, Hahn PF. Cystic pancreatic lesions: a simple imaging-based classification system for guiding management. Radiographics. Nov-Dec 2005;25(6):1471-84. [Medline].
Soliani P, Franzini C, Ziegler S, Del Rio P, Dell'Abate P, Piccolo D, et al. Pancreatic pseudocysts following acute pancreatitis: risk factors influencing therapeutic outcomes. JOP. Sep 2004;5(5):338-47. [Medline].
Vitas GJ, Sarr MG. Selected management of pancreatic pseudocysts: operative versus expectant management. Surgery. Feb 1992;111(2):123-30. [Medline].
Warshaw AL, Compton CC, Lewandrowski K, Cardenosa G, Mueller PR. Cystic tumors of the pancreas. New clinical, radiologic, and pathologic observations in 67 patients. Ann Surg. Oct 1990;212(4):432-43; discussion 444-5. [Medline].
Warshaw AL, Rutledge PL. Cystic tumors mistaken for pancreatic pseudocysts. Ann Surg. Apr 1987;205(4):393-8. [Medline].
Yeo CJ, Bastidas JA, Lynch-Nyhan A, Fishman EK, Zinner MJ, Cameron JL. The natural history of pancreatic pseudocysts documented by computed tomography. Surg Gynecol Obstet. May 1990;170(5):411-7. [Medline].

