eMedicine Specialties > General Surgery > Colorectal

Gardner Syndrome: Follow-up

Author: Hemant Singhal, MD, MBBS, FRCSE, FRCS(C), Senior Lecturer, Department of Surgery, Imperial College School of Medicine, UK; Consultant Surgeon, Northwick Park and St Marks Hospitals, UK
Coauthor(s): Scott M Hovis, MD, Staff Physician, Department of General Surgery, Spartanburg Regional Medical Center; Sidney R Steinberg, MD, FACS, Program Director, Department of General Surgery, Spartanburg Regional Healthcare System; Consulting Surgeon, Department of Surgery, WG Hefner Veterans Affairs Medical Center
Contributor Information and Disclosures

Updated: Feb 26, 2009

Outcome and Prognosis

The 5-year survival rate for patients older than 45 years who do not receive operative management is 0%.

The 5-year survival rate for patients who undergo proctocolectomy and mucosectomy with IPAA is nearly 100%.

The recurrence rate in 20 years after total colectomy with IRA is 30%. The recurrence rate in 30 years after total colectomy with IRA is 45%.

Future and Controversies

To recapitulate the debate, which has been ongoing since the 1970s, the surgical choices for prophylaxis in familial adenomatous polyposis are proctocolectomy8 with ileostomy versus proctocolectomy, mucosectomy, and IPAA versus total colectomy with IRA.

 
Acknowledgments

The authors and editors of eMedicine gratefully acknowledge the contributions of previous coauthor, William T Cummins, MD, to the development and writing of this article.



More on Gardner Syndrome

Overview: Gardner Syndrome
Workup: Gardner Syndrome
Treatment: Gardner Syndrome
Follow-up: Gardner Syndrome
Multimedia: Gardner Syndrome
References
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References

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Further Reading

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Keywords

Gardner syndrome, colon cancer, colorectal cancer, rectal cancer, familial adenomatous polyposis, colon polyps, adenomatous, polyposis, desmoid tumor, colon polyps, adenomatous polyposis, epidermoid cyst, Gardner's syndrome, FAP, colorectal carcinoma, APC gene, familial polyposis coli, FPC, hereditary adenomatosis of the colon and rectum, HACR, colon adenoma, rectum adenoma, rectal adenoma, colon tumor, rectum tumor, colon mass, rectum mass, rectal mass, rectal carcinoma, colon carcinoma, rectum carcinoma, intestinal polyposis, desmoid, rectal polyps

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Contributor Information and Disclosures

Author

Hemant Singhal, MD, MBBS, FRCSE, FRCS(C), Senior Lecturer, Department of Surgery, Imperial College School of Medicine, UK; Consultant Surgeon, Northwick Park and St Marks Hospitals, UK
Hemant Singhal, MD, MBBS, FRCSE, FRCS(C) is a member of the following medical societies: Royal College of Physicians and Surgeons of Canada and Royal College of Surgeons of Edinburgh
Disclosure: Nothing to disclose.

Coauthor(s)

Scott M Hovis, MD, Staff Physician, Department of General Surgery, Spartanburg Regional Medical Center
Scott M Hovis, MD is a member of the following medical societies: American Medical Association and South Carolina Medical Association
Disclosure: Nothing to disclose.

Sidney R Steinberg, MD, FACS, Program Director, Department of General Surgery, Spartanburg Regional Healthcare System; Consulting Surgeon, Department of Surgery, WG Hefner Veterans Affairs Medical Center
Sidney R Steinberg, MD, FACS is a member of the following medical societies: American College of Surgeons, American Medical Association, Association for Surgical Education, South Carolina Medical Association, and Southeastern Surgical Congress
Disclosure: Nothing to disclose.

Pharmacy Editor

Francisco Talavera, PharmD, PhD, Senior Pharmacy Editor, eMedicine
Disclosure: Nothing to disclose.

Managing Editor

David L Morris, MD, PhD, Professor, Department of Surgery, St George Hospital, University of New South Wales, Australia
Disclosure: Nothing to disclose.

CME Editor

Paolo Zamboni, MD, Professor of Surgery, Chief of Day Surgery Unit, Chair of Vascular Diseases Center, University of Ferrara, Italy
Paolo Zamboni, MD is a member of the following medical societies: American Venous Forum and New York Academy of Sciences
Disclosure: Nothing to disclose.

Chief Editor

John Geibel, MD, DSc, MA, Vice Chairman, Professor, Department of Surgery, Section of Gastrointestinal Medicine and Department of Cellular and Molecular Physiology, Yale University School of Medicine; Director of Surgical Research, Department of Surgery, Yale-New Haven Hospital
John Geibel, MD, DSc, MA is a member of the following medical societies: American Gastroenterological Association, American Physiological Society, American Society of Nephrology, Association for Academic Surgery, International Society of Nephrology, New York Academy of Sciences, and Society for Surgery of the Alimentary Tract
Disclosure: AMGEN Royalty Other

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