Close
New

Medscape is available in 5 Language Editions – Choose your Edition here.

 

Abdominal Abscess Treatment & Management

  • Author: Alan A Saber, MD, MS, FACS; Chief Editor: John Geibel, MD, DSc, MSc, MA  more...
 
Updated: Jun 21, 2016
 

Approach Considerations

Contraindications for surgical correction of abdominal abscesses are based on the patient’s comorbidities and on the individual’s ability to tolerate surgery.

Next

Pharmacologic Therapy

Pharmacologic therapy involves the empiric administration of parenteral empiric antibiotics. This should be initiated before abscess drainage and concluded when all systemic signs of sepsis have resolved. Because abscess fluid usually contains a mixture of aerobic and anaerobic organisms, initial empiric therapy must be directed against both types of microbes. This may be accomplished with antibiotic combination therapy or with broad-spectrum single-agent therapy. Specific therapy is then guided by the results of cultures retrieved from the abscess.[5]

In patients who are immunosuppressed, candidal species may play an important pathogenic role, and treatment with amphotericin B may be indicated.

Previous
Next

Percutaneous Abscess Drainage

Drainage of pus is mandatory and is the first line of defense against progressive sepsis. Percutaneous computed tomography (CT)-guided catheter drainage has become the standard treatment of most intra-abdominal abscesses (see the image below). It avoids anesthesia and possibly difficult laparotomy, prevents the possibility of wound complications from open surgery, and may reduce the length of hospitalization. It also obviates the possibility of contaminating other areas within the peritoneal cavity.

Percutaneous computed tomography (CT) scan–guided Percutaneous computed tomography (CT) scan–guided drainage of postoperative subhepatic collection.

CT-guided drainage delineates the abscess cavity and may provide safe access for percutaneous drainage. When performed by experienced physicians, it also prevents the possibility of injury to adjacent viscera or blood vessels.[10, 11]

A diagnostic needle aspiration initially is performed to confirm the presence of pus, which makes Gram staining and culture possible. A large-bore drainage catheter is then placed in the most dependent position.

In patients who are critically ill, initial percutaneous drainage can control sepsis and improve hemodynamics before definitive surgical treatment (if this becomes necessary). Initial catheter drainage also may drain a peridiverticular abscess enough to make a single-stage resection and bowel anastomosis possible, thus avoiding multiple-stage procedures. A visualized collection may be sterile (eg, bile, hematoma) or infected, and CT-guided aspiration is most helpful in distinguishing between these states.[12]

After drainage, clinical improvement should occur within 48-72 hours. Lack of improvement within this time frame mandates repeat CT to check for additional abscesses. Surgical drainage becomes mandatory if residual fluid cannot be evacuated with catheter irrigation, manipulation, or additional drain placement.

Criteria for removal of percutaneous catheters include resolution of sepsis signs, minimal drainage from the catheter, and resolution of the abscess cavity as demonstrated by ultrasonography or CT. Persistent drainage usually reflects the presence of an enteric fistula, and CT with contrast should be performed. Frequently, this fistula can be documented by sinography.

Complications of percutaneous drainage include bleeding or inadvertent puncture of the gastrointestinal (GI) tract.

Percutaneous drainage is effective in 90% of patients who have a single unilocular abscess with no enteral communication. Complex abscesses that include multiple loculations or interloop abscesses or those associated with an enteric fistula may necessitate surgery. Surgical intervention also may be indicated for abscesses with tenacious contents, such as infected hematoma, infected pancreatic necrosis, or fungal abscesses.

Previous
Next

Laparoscopic or Open Abscess Drainage

If percutaneous drainage fails or if collections are not amenable to catheter drainage, surgical drainage is an option. The surgical approach may be either laparoscopic or open (laparotomic).

Laparoscopic drainage for a massive intra-abdominal abscess is minimally invasive, permitting exploration of the abdominal cavity without the use of a wide incision; purulent exudate can be aspirated under direct vision.[13]

With accurate preoperative localization, direct open surgical drainage may be possible through an extraperitoneal open approach. This technique reduces the risk of bowel injury, contamination spread, and bleeding. It also allows for a faster return of bowel function.

The transperitoneal open approach is made safer by the judicious use of preoperative antibiotics. Although contamination of otherwise uninfected sites remains a major concern, this complication is particularly reduced if the organisms involved are sensitive to the chosen drugs. Transabdominal exploration of the entire peritoneal cavity allows fibrin debridement. It also permits complete bowel mobilization to locate and drain all synchronous abscesses, which occur in as many as 23% of patients.

Transperitoneal exploration is indicated for multiple abscesses not amenable to CT-guided drainage, such as interloop collections or an enteric fistula feeding the abscess. In the latter situation, draining the abscesses with an enteric communication may be possible for several days before a laparotomy is performed to control the fistula. This may allow some resolution of the inflammatory process, thus making surgery less difficult.

Pelvic abscesses often are palpable as tender, fluctuant masses impinging on the vagina or rectum. Draining these abscesses transvaginally or transrectally is best to avoid the transabdominal approach.

During the course of a laparotomy, the surgeon must use digital or direct exploration to be certain that all loculations are broken down and that all debris (eg, hematoma, necrotic tissue) is evacuated. Irrigation must be complete, and a Penrose or sump drain should be placed to allow continued evacuation and collapse of the abscess cavity postoperatively.

Improved clinical findings within 3 days after treatment indicate successful drainage. Failure to improve may indicate inadequate drainage or another source of sepsis. If left untreated, the septic state inevitably produces multiple organ failure.

The transabdominal open approach to intra-abdominal abscesses can be exceedingly difficult. Matted bowel, adhesions, and loss of anatomic integrity can pose severe problems. This is especially true when susceptible viscera, such as a loop of small bowel, intermittently adhere to the abscess wall or cavity. Therefore, whenever possible, CT-guided drainage is a valuable initial step.

Previous
 
 
Contributor Information and Disclosures
Author

Alan A Saber, MD, MS, FACS FASMBS, Director of Bariatric and Metabolic Surgery, University Hospitals Case Medical Center; Surgical Director, Bariatric Surgery, Metabolic and Nutrition Center, University Hospitals Digestive Health Institute; Associate Professor of Surgery, Case Western Reserve University School of Medicine

Alan A Saber, MD, MS, FACS is a member of the following medical societies: American College of Surgeons, American Society for Metabolic and Bariatric Surgery, American Society for Gastrointestinal Endoscopy

Disclosure: Nothing to disclose.

Coauthor(s)

Raymond D LaRaja, MD, MD 

Raymond D LaRaja, MD, MD is a member of the following medical societies: American College of Surgeons, American Medical Association, New York Academy of Medicine, New York County Medical Society

Disclosure: Nothing to disclose.

Chief Editor

John Geibel, MD, DSc, MSc, MA Vice Chair and Professor, Department of Surgery, Section of Gastrointestinal Medicine, and Department of Cellular and Molecular Physiology, Yale University School of Medicine; Director, Surgical Research, Department of Surgery, Yale-New Haven Hospital; American Gastroenterological Association Fellow

John Geibel, MD, DSc, MSc, MA is a member of the following medical societies: American Gastroenterological Association, American Physiological Society, American Society of Nephrology, Association for Academic Surgery, International Society of Nephrology, New York Academy of Sciences, Society for Surgery of the Alimentary Tract

Disclosure: Received royalty from AMGEN for consulting; Received ownership interest from Ardelyx for consulting.

Acknowledgements

H Scott Bjerke, MD, FACS Clinical Associate Professor, Department of Surgery, University of Missouri-Kansas City School of Medicine; Medical Director of Trauma Services, Research Medical Center; Clinical Professor, Department of Surgery, Kansas City University of Medicine and Biosciences

H Scott Bjerke, MD, FACS is a member of these medical societies: American Association for the History of Medicine, American Association for the Surgery of Trauma, American College of Surgeons, Association for Academic Surgery, Eastern Association for the Surgery of Trauma, Midwest Surgical Association, National Association of EMS Physicians, Pan-Pacific Surgical Association, Royal Society of Medicine, Southwestern Surgical Congress, and Wilderness Medical Society

Disclosure: Nothing to disclose.

Michael A Grosso, MD Consulting Staff, Department of Cardiothoracic Surgery, St Francis Hospital

Michael A Grosso, MD is a member of the following medical societies: American College of Surgeons, Society of Thoracic Surgeons, and Society of University Surgeons

Disclosure: Nothing to disclose.

Francisco Talavera, PharmD, PhD, Adjunct Assistant Professor, University of Nebraska Medical Center College of Pharmacy; Editor-in-Chief, Medscape Drug Reference

Disclosure: Medscape Reference Salary Employment

References
  1. Eberhardt JM, Kiran RP, Lavery IC. The impact of anastomotic leak and intra-abdominal abscess on cancer-related outcomes after resection for colorectal cancer: a case control study. Dis Colon Rectum. 2009 Mar. 52(3):380-6. [Medline].

  2. Varcus F, Lazar F, Beuran M, Lica I, Turculet C, Nicolau E, et al. Laparoscopic treatment of perforated duodenal ulcer - a multicentric study. Chirurgia (Bucur). 2013 Mar-Apr. 108(2):172-6. [Medline].

  3. L V, Rao V D, Rao M S, Y M. "Toxic Pancreatitis with an Intra-Abdominal Abscess which was Caused by Organophosphate Poisoning (OP)". J Clin Diagn Res. 2013 Feb. 7(2):366-8. [Medline]. [Full Text].

  4. Yang YM, Tian XD, Zhuang Y, Wang WM, Wan YL, Huang YT. Risk factors of pancreatic leakage after pancreaticoduodenectomy. World J Gastroenterol. 2005 Apr 28. 11(16):2456-61. [Medline].

  5. Hasper D, Schefold JC, Baumgart DC. Management of severe abdominal infections. Recent Pat Antiinfect Drug Discov. 2009 Jan. 4(1):57-65. [Medline].

  6. Malangoni MA, Shumate CR, Thomas HA, Richardson JD. Factors influencing the treatment of intra-abdominal abscesses. Am J Surg. 1990 Jan. 159(1):167-71. [Medline].

  7. Greenberg J, Arnell TD. Diverticular abscess presenting as an incarcerated inguinal hernia. Am Surg. 2005 Mar. 71(3):208-9. [Medline].

  8. Pedrazzoli S, Liessi G, Pasquali C, Ragazzi R, Berselli M, Sperti C. Postoperative pancreatic fistulas: preventing severe complications and reducing reoperation and mortality rate. Ann Surg. 2009 Jan. 249(1):97-104. [Medline].

  9. van Randen A, Bipat S, Zwinderman AH, Ubbink DT, Stoker J, Boermeester MA. Acute appendicitis: meta-analysis of diagnostic performance of CT and graded compression US related to prevalence of disease. Radiology. 2008 Oct. 249(1):97-106. [Medline].

  10. Hemming A, Davis NL, Robins RE. Surgical versus percutaneous drainage of intra-abdominal abscesses. Am J Surg. 1991 May. 161(5):593-5. [Medline].

  11. Rypens F, Dubois J, Garel L, Deslandres C, Saint-Vil D. Percutaneous drainage of abdominal abscesses in pediatric Crohn's disease. AJR Am J Roentgenol. 2007 Feb. 188(2):579-85. [Medline].

  12. Laborda A, De Gregorio MA, Miguelena JM, Medrano J, Gómez-Arrue J, Serrano C, et al. Percutaneous treatment of intrabdominal abscess: urokinase versus saline serum in 100 cases using two surgical scoring systems in a randomized trial. Eur Radiol. 2009 Jul. 19(7):1772-9. [Medline].

  13. Kimura T, Shibata M, Ohhara M. Effective laparoscopic drainage for intra-abdominal abscess not amenable to percutaneous approach: report of two cases. Dis Colon Rectum. 2005 Feb. 48(2):397-9. [Medline].

 
Previous
Next
 
Percutaneous computed tomography (CT) scan–guided drainage of postoperative subhepatic collection.
Contrast-enhanced computed tomography (CT) scan of infected pancreatic pseudocyst (which can develop from acute necrotizing pancreatitis and give rise to an abscess).
A 35-year-old man with a history of Crohn disease presented with pain and swelling in the right abdomen. Figure A shows a thickened loop of terminal ileum adherent to the right anterior abdominal wall. In figure B, the right anterior abdominal wall, adjacent to the inflamed terminal ileum, is markedly thickened and edematous. Figure C shows a right lower quadrant abdominal wall abscess and enteric fistula (confirmed by the presence of enteral contrast in the abdominal wall).
 
 
 
All material on this website is protected by copyright, Copyright © 1994-2016 by WebMD LLC. This website also contains material copyrighted by 3rd parties.