eMedicine Specialties > Hematology > Red Blood Cells and Disorders

Anemia: Multimedia

Author: Marcel E Conrad, MD, (Retired) Distinguished Professor of Medicine, University of South Alabama
Contributor Information and Disclosures

Updated: Mar 11, 2008

Multimedia

Anemia. Decreased production of red blood cells i...Media file 1: Anemia. Decreased production of red blood cells is suggested in certain patients with anemia. Bone marrow biopsy specimen allows categorization of patients with anemia without evidence of blood loss or hemolysis into 3 groups: aplastic or hypoplastic disorder, hyperplastic disorder, or infiltration disorder. Each category and its associated causes are listed in this image.
Anemia. Decreased production of red blood cells i...

Anemia. Decreased production of red blood cells is suggested in certain patients with anemia. Bone marrow biopsy specimen allows categorization of patients with anemia without evidence of blood loss or hemolysis into 3 groups: aplastic or hypoplastic disorder, hyperplastic disorder, or infiltration disorder. Each category and its associated causes are listed in this image.

Microcytic anemia.Media file 2: Microcytic anemia.
Microcytic anemia.

Microcytic anemia.

Peripheral smear showing ovalocytes, macrocytes, ...Media file 3: Peripheral smear showing ovalocytes, macrocytes, and a hypersegmented polymorphonuclear leukocyte.
Peripheral smear showing ovalocytes, macrocytes, ...

Peripheral smear showing ovalocytes, macrocytes, and a hypersegmented polymorphonuclear leukocyte.

Peripheral smear showing classic spherocytes with...Media file 4: Peripheral smear showing classic spherocytes with loss of central pallor in the erythrocytes.
Peripheral smear showing classic spherocytes with...

Peripheral smear showing classic spherocytes with loss of central pallor in the erythrocytes.

Peripheral smear showing multiple inclusion bodie...Media file 5: Peripheral smear showing multiple inclusion bodies inside the red blood cells.
Peripheral smear showing multiple inclusion bodie...

Peripheral smear showing multiple inclusion bodies inside the red blood cells.

Bone marrow aspirate containing increased numbers...Media file 6: Bone marrow aspirate containing increased numbers of plasma cells.
Bone marrow aspirate containing increased numbers...

Bone marrow aspirate containing increased numbers of plasma cells.

Bone marrow aspirate showing erythroid hyperplasi...Media file 7: Bone marrow aspirate showing erythroid hyperplasia and many binucleated erythroid precursors.
Bone marrow aspirate showing erythroid hyperplasi...

Bone marrow aspirate showing erythroid hyperplasia and many binucleated erythroid precursors.

More on Anemia

Overview: Anemia
Differential Diagnoses & Workup: Anemia
Treatment & Medication: Anemia
Follow-up: Anemia
Multimedia: Anemia
References
Further Reading

References

  1. Servilla KS, Singh AK, Hunt WC, et al. Anemia management and association of race with mortality and hospitalization in a large not-for-profit dialysis organization. Am J Kidney Dis. Sep 2009;54(3):498-510. [Medline].

  2. Adebisi OY, Strayhorn G. Anemia in pregnancy and race in the United States: blacks at risk. Fam Med. Oct 2005;37(9):655-62. [Medline].

  3. Silva DG, Priore SE, Franceschini Sdo C. Risk factors for anemia in infants assisted by public health services: the importance of feeding practices and iron supplementation. J Pediatr (Rio J). Mar-Apr 2007;83(2):149-56. [Medline].

  4. Oliveira MA, Osório MM, Raposo MC. Socioeconomic and dietary risk factors for anemia in children aged 6 to 59 months. J Pediatr (Rio J). Jan-Feb Epub 2007 Jan 12 2007;83(1):39-46. [Medline].

  5. Stamatoyannopoulos G, Majerus PW, Perimutter RM. The Molecular Basis of Blood Diseases. Philadelphia, Pa: WB Saunders Co; 2000.

  6. Kuku I, Kaya E, Yologlu S, Gokdeniz R, Baydin A. Platelet counts in adults with iron deficiency anemia. Platelets. Aug 3 2009;1-5. [Medline].

  7. Dhar R, Zazulia AR, Videen TO, et al. Red blood cell transfusion increases cerebral oxygen delivery in anemic patients with subarachnoid hemorrhage. Stroke. Sep 2009;40(9):3039-44. [Medline].

  8. Beutler E, Lichtman MA, Coller BS. Williams Hematology. 6th ed. New York, NY: McGraw-Hill; 2000.

  9. Deal JA, Carlson MC, Xue QL, Fried LP, Chaves PH. Anemia and 9-year domain-specific cognitive decline in community-dwelling older women: The Women's Health and Aging Study II. J Am Geriatr Soc. Sep 2009;57(9):1604-11. [Medline].

  10. Hoffman R, Benz EJ Jr, Shattil SJ. Hematology: Basic Principles and Practice. New York, NY: Churchill Livingstone; 1998.

  11. Jandl JH. Blood: Textbook of Hematology. 2nd ed. Baltimore, Md: Lippincott Williams & Wilkins; 1996.

  12. Lee GR, Foerster J, Lukens J. Wintrobe's Clinical Hematology. 10th ed. Baltimore, Md:. Lippincott, Williams & Wilkins;1999.

  13. Lin JD, Lin PY, Lin LP, et al. Prevalence and associated risk factors of anemia in children and adolescents with intellectual disabilities. Res Dev Disabil. Aug 28 2009;epub ahead of print. [Medline].

  14. Mozaffari-Khosravi H, Noori-Shadkam M, Fatehi F, Naghiaee Y. Once weekly low-dose iron supplementation effectively improved iron status in adolescent girls. Biol Trace Elem Res. Aug 4 2009;epub ahead of print. [Medline].

Further Reading

Related eMedicine Topics

Clinical Trials

Clinical Guidelines

Keywords

anemia, red blood cell count, RBC, hemoglobin concentration, Hb, hematocrit, Hct, reticulocytes, erythrocytes, sickle cell anemia, thalassemia, malaria, hookworm, chronic infections, iron deficiency, folic acid deficiency, mean corpuscular volume, MCV, mean corpuscular hemoglobin concentration, MCHC, blood loss, increased RBC destruction, hemolysis,

decreased production of RBCs, heme iron, decrease in red blood cell, decrease in RBC mass, hereditary spherocytosis, glucose-6-phosphate dehydrogenase deficiency, G-6-PD deficiency, chronic hemolytic anemia, pernicious anemia, calf cramps, hemoglobinopathies, sex-linked sideroblastic anemias, Fanconi syndrome, use of aspirin, use of nonsteroidal anti-inflammatory drugs, use of NSAIDs, use of Coumadin,

gastrointestinal bleeding, tarry stools, neoplasms of colon, hemorrhoidal blood loss, pagophagia, cramps in the calves, sore tongue, cheilosis, steatorrhea, coagulopathy, thrombocytopenia, bleeding disorders, hypothyroidism, lupus erythematosus, paroxysmal cold hemoglobinuria, macroglobulinemias, march hemoglobinuria, paroxysmal nocturnal hemoglobinuria, endocrinopathy, pallor, hepatomegaly

splenomegaly, bacterial endocarditis, enzyme abnormalities of the glycolytic pathways, hemolytic uremic syndrome, thrombotic thrombocytopenic purpura, toxoplasmosis, leishmaniasis, gram-negative sepsis, cytomegalovirus, infectious mononucleosis, hepatitis, collagen vascular diseases, neoplasia, hepatic disease, renal disease, malignancies, chronic diseases

megaloblastic anemia, aplastic anemia, frostbite, burns, trauma, hemorrhage, generalized malnutrition, folate deficiency, vitamin B-12 deficiency, Fanconi anemia, abetalipoproteinemia, hereditary xerocytosis, Rh null disease, congenital dyserythropoietic anemia

Contributor Information and Disclosures

Author

Marcel E Conrad, MD, (Retired) Distinguished Professor of Medicine, University of South Alabama
Marcel E Conrad, MD is a member of the following medical societies: Alpha Omega Alpha, American Association for the Advancement of Science, American Association of Blood Banks, American Chemical Society, American College of Physicians, American Physiological Society, American Society for Clinical Investigation, American Society of Hematology, Association of American Physicians, Association of Military Surgeons of the US, International Society of Hematology, Society for Experimental Biology and Medicine, and Southwest Oncology Group
Disclosure: No financial interests None None

Medical Editor

Jose A Perez Jr, MD, MSEd, MBA, Consulting Physician, Department of Internal Medicine, Residency Director, Vice Chair of Education Department of Medicine, The Methodist Hospital, Houston; Associate Professor of Clinical Medicine, Weill Cornell Medical College
Jose A Perez Jr, MD, MSEd, MBA is a member of the following medical societies: American College of Physician Executives, American College of Physicians, and Society of General Internal Medicine
Disclosure: Nothing to disclose.

Pharmacy Editor

Francisco Talavera, PharmD, PhD, Senior Pharmacy Editor, eMedicine
Disclosure: eMedicine Salary Employment

Managing Editor

Ronald A Sacher, MB, BCh, MD, FRCPC, Professor, Internal Medicine and Pathology, Director, Hoxworth Blood Center, University of Cincinnati Academic Health Center
Ronald A Sacher, MB, BCh, MD, FRCPC is a member of the following medical societies: American Society of Hematology
Disclosure: Glaxo Smith Kline Honoraria Speaking and teaching; Talecris Honoraria Board membership

CME Editor

Rajalaxmi McKenna, MD, FACP, Southwest Medical Consultants, SC, Department of Medicine, Good Samaritan Hospital, Advocate Health Systems
Rajalaxmi McKenna, MD, FACP is a member of the following medical societies: American Society of Clinical Oncology, American Society of Hematology, and International Society on Thrombosis and Haemostasis
Disclosure: Nothing to disclose.

Chief Editor

Emmanuel C Besa, MD, Professor, Department of Medicine, Division of Hematologic Malignancies, Kimmel Cancer Center, Thomas Jefferson University
Emmanuel C Besa, MD is a member of the following medical societies: American Association for Cancer Education, American College of Clinical Pharmacology, American Federation for Medical Research, American Society of Hematology, and New York Academy of Sciences
Disclosure: Nothing to disclose.

 
 
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