Osgood-Schlatter Disease Workup
- Author: J Andy Sullivan, MD; Chief Editor: Craig C Young, MD more...
Histologic Findings
Lazerte and Rapp, in examining resected operative specimens in patients with Osgood-Schlatter disease, demonstrated avulsion fractures in the distal portion of the tibial tubercle.[9]
Ehrenborg examined histologic specimens of bone excised from portions of tibial tubercles and found viable cancellous bone without evidence of inflammation or avascular necrosis.[10, 11]
Approach Considerations
Laboratory evaluation is not indicated for Osgood-Schlatter disease (OSD) unless other diagnoses are being entertained.
Imaging studies are not required to make a diagnosis of OSD; however, they often are used to rule out osteomyelitis, tumors, and other pathologies. Bone scanning may demonstrate increased uptake in the area of the tibial tuberosity.
Radiographs
Not all patients with Osgood-Schlatter disease (OSD) need radiography, since the diagnosis is clinical. However, plain films are helpful for ruling out other etiologies, such as neoplasm, acute tibial apophyseal fracture, and infection. In addition, radiographs may indicate:
- Superficial ossicle in the patellar tendon
- Irregular ossification of the proximal tibial tuberosity
- Calcification within the patellar tendon
- Thickening of the patellar tendon
- Soft-tissue edema proximal to the tibial tuberosity
The Osgood-Schlatter lesion is best seen on the lateral view, with the knee in slight internal rotation of 10-20°.
When radiographs are obtained, the most common finding is that the knee films are normal, especially if the child is in the preossification phase.
The acute phase of OSD may reveal a prominent and elevated tibial tubercle with anterior soft-tissue swelling.
In severe cases, radiographs may reveal radiodense fragments or ossicles separated from the tibial tuberosity. (An ossicle is seen in the image below.)
Radiograph of a patient who is skeletally mature. Note that the tibial tubercle is enlarged and there is an ossicle. A bursa was overlying this. Occasionally, the radiographs may reveal irregularity, fragmentation (seen below), or increased density of the ossification of the tibial tubercle. This pattern may be a normal variant in asymptomatic children.
Radiograph of a patient who is skeletally immature. The tubercle is elongated and fragmented Other Imaging Modalities
Ultrasonography may reveal a normal tubercle and signal changes consistent with thickening (more echogenic) in the patellar tendon and hypoechoic area of the adjacent soft tissue.[7, 8]
Computed tomography (CT) scanning or MRI may reveal changes at the insertion of the patellar tendon.
MRI may assist in diagnosis of an atypical presentation. It may eventually play a role in staging of the disease and prognosticating the clinical course. However, MRI’s role in diagnosis, prognostication, and management is currently limited.[6]
Pommering TL, Kluchurosky L. Overuse injuries in adolescents. Adolesc Med State Art Rev. May 2007;18(1):95-120, ix. [Medline].
Krause BL, Williams JP, Catterall A. Natural history of Osgood-Schlatter disease. J Pediatr Orthop. Jan-Feb 1990;10(1):65-8. [Medline].
Weiss JM, Jordan SS, Andersen JS, Lee BM, Kocher M. Surgical treatment of unresolved Osgood-Schlatter disease: ossicle resection with tibial tubercleplasty. J Pediatr Orthop. Oct-Nov 2007;27(7):844-7. [Medline].
Demirag B, Ozturk C, Yazici Z, Sarisozen B. The pathophysiology of Osgood-Schlatter disease: a magnetic resonance investigation. J Pediatr Orthop B. Nov 2004;13(6):379-82. [Medline].
Kujala UM, Kvist M, Heinonen O. Osgood-Schlatter's disease in adolescent athletes. Retrospective study of incidence and duration. Am J Sports Med. Jul-Aug 1985;13(4):236-41. [Medline].
Gholve PA, Scher DM, Khakharia S, Widmann RF, Green DW. Osgood Schlatter syndrome. Curr Opin Pediatr. Feb 2007;19(1):44-50. [Medline].
Ducher G, Cook J, Spurrier D, Coombs P, Ptasznik R, Black J, et al. Ultrasound imaging of the patellar tendon attachment to the tibia during puberty: a 12-month follow-up in tennis players. Scand J Med Sci Sports. Feb 2010;20(1):e35-40. [Medline].
Ducher G, Cook J, Lammers G, Coombs P, Ptazsnik R, Black J, et al. The ultrasound appearance of the patellar tendon attachment to the tibia in young athletes is conditional on gender and pubertal stage. J Sci Med Sport. Jan 2010;13(1):20-3. [Medline].
LAZERTE GD, RAPP IH. Pathogenesis of Osgood-Schlatter's disease. Am J Pathol. Jul-Aug 1958;34(4):803-15. [Medline]. [Full Text].
EHRENBORG G. The Osgood-Schlatter lesion. A clinical study of 170 cases. Acta Chir Scand. Aug 1962;124:89-105. [Medline].
EHRENBORG G. The Osgood-Schlatter lesion. A clinical and experimental study. Acta Chir Scand Suppl. 1962;Suppl 288:1-36. [Medline].
Pihlajamäki HK, Mattila VM, Parviainen M, Kiuru MJ, Visuri TI. Long-term outcome after surgical treatment of unresolved Osgood-Schlatter disease in young men. J Bone Joint Surg Am. Oct 2009;91(10):2350-8. [Medline].
Binazzi R, Felli L, Vaccari V, Borelli P. Surgical treatment of unresolved Osgood-Schlatter lesion. Clin Orthop Relat Res. Apr 1993;202-4. [Medline].
Orava S, Malinen L, Karpakka J, Kvist M, Leppilahti J, Rantanen J, et al. Results of surgical treatment of unresolved Osgood-Schlatter lesion. Ann Chir Gynaecol. 2000;89(4):298-302. [Medline].
Trail IA. Tibial sequestrectomy in the management of Osgood-Schlatter disease. J Pediatr Orthop. Sep-Oct 1988;8(5):554-7. [Medline].

