eMedicine Specialties > Hematology > Coagulation, Hemostasis, and Disorders
Dysfibrinogenemia: Follow-up
Updated: Apr 13, 2006
Follow-up
Prognosis
- Prognosis is good for patients with congenital dysfibrinogenemias. Events of bleeding or thrombosis are usually relatively mild.
- Acquired dysfibrinogenemia carries a worse prognosis because it is due to a severely damaged liver.
Patient Education
- Educate patients with congenital dysfibrinogenemias that it is an inherited condition and other family members may also be affected.
Miscellaneous
Medicolegal Pitfalls
- Failure to diagnose and treat bleeding or thrombosis
- Failure to counsel patients that other family members may be affected
Special Concerns
- Women who experience multiple miscarriages may benefit from prophylactic administration of cryoprecipitate.
More on Dysfibrinogenemia |
| Overview: Dysfibrinogenemia |
| Differential Diagnoses & Workup: Dysfibrinogenemia |
| Treatment & Medication: Dysfibrinogenemia |
Follow-up: Dysfibrinogenemia |
| References |
| « Previous Page |
References
Bazzan M, Tamponi G, Vaccarino A, et al. Natural and acquired inhibitors of hemostasis in selected symptomatic outpatients with venous thromboembolic disease. Haematologica. Jul-Aug 1997;82(4):420-2. [Medline].
Galanakis DK. Inherited dysfibrinogenemia: emerging abnormal structure associations with pathologic and nonpathologic dysfunctions. Semin Thromb Hemost. 1993;19(4):386-95. [Medline].
Haverkate F, Samama M. Familial dysfibrinogenemia and thrombophilia. Report on a study of the SSC Subcommittee on Fibrinogen. Thromb Haemost. Jan 1995;73(1):151-61. [Medline].
Martinez J. Quantitative and qualitative disorders of fibrinogen. In: Hoffman, et al, eds. Hematology: Basic Principles and Procedures. 2nd ed. Philadelphia, Pa: Churchill Livingstone;1995:1703-13, 2011-13.
Martinez J. Congenital dysfibrinogenemia. Curr Opin Hematol. Sep 1997;4(5):357-65. [Medline].
Mori T, Ikeda Y. [Acquired dysfibrinogenemia]. Ryoikibetsu Shokogun Shirizu. 1998;(21 Pt 2):529-31. [Medline].
Mosesson MW. Dysfibrinogenemia and thrombosis. Semin Thromb Hemost. 1999;25(3):311-9. [Medline].
Rodgers GM, Greenberg CS. Inherited coagulation disorders. In: Lee GR, Foerster J, Lukens J, Paraskevas F, Greer JP, Rodgers GM, eds. Wintrobe's Clinical Hematology. 10th ed. Baltimore, Md: Williams & Wilkins;1999:1702-3.
Schorer AE, Singh J, Basara ML. Dysfibrinogenemia: a case with thrombosis (fibrinogen Richfield) and an overview of the clinical and laboratory spectrum. Am J Hematol. Nov 1995;50(3):200-8. [Medline].
Further Reading
Keywords
congenital dysfibrinogenemia, cirrhosis, hepatoma, hepatitis, abnormal clot formation, fibrinopeptide, fibrinolysis, thrombotic events, fibrin, dysfibrinogenemia of liver disease, acquired dysfibrinogenemia
Follow-up: Dysfibrinogenemia