eMedicine Specialties > Hematology > Immune System and Disorders
Granulocytopenia: Follow-up
Updated: Apr 8, 2009
Follow-up
Deterrence/Prevention:
- Patients with neutropenia should avoid exposure to people with respiratory tract infections.
- Neutropenic individuals should avoid overcrowded areas.
- Patients should wear a facemask in public places if their ANC is less than 1000/mm3.
Prognosis:
- The prognosis of a patient with neutropenia depends on the underlying cause of their neutropenia. Improved broad-spectrum antibiotic agents, combined with improved supportive care, have improved the prognosis for most patients with severe neutropenia. Ultimately, patient survival depends on the recovery of adequate neutrophil numbers.
Miscellaneous
Medicolegal Pitfalls
- Failure to treat neutropenic fevers on an outpatient basis with extreme caution
- Failure of the neutropenic individual to be reliable and failure to have strong support at home by family and friends
- Failure to fit the patient criteria for low-risk neutropenia (see Medical Care)
- Failure to properly inform the patient about the seriousness and complications of neutropenic infections
- Failure to acknowledge a fever and to offer appropriate on-time care, thereby allowing the neutropenic patient's condition to become life threatening
More on Granulocytopenia |
| Overview: Granulocytopenia |
| Differential Diagnoses & Workup: Granulocytopenia |
| Treatment & Medication: Granulocytopenia |
Follow-up: Granulocytopenia |
| Multimedia: Granulocytopenia |
| References |
| Further Reading |
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References
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[Best Evidence] Massey E, Paulus U, Doree C, Stanworth S. Granulocyte transfusions for preventing infections in patients with neutropenia or neutrophil dysfunction. Cochrane Database Syst Rev. Jan 21 2009;CD005341. [Medline]. [Full Text].
Further Reading
Related eMedicine Topics
Best Evidence
- Massey E, Paulus U, Doree C, Stanworth S. Granulocyte transfusions for preventing infections in patients with neutropenia or neutrophil dysfunction. Cochrane Database Syst Rev. Jan 21 2009;CD005341. [Medline]. [Full Text].
Clinical Trials
- FDG-PET/CT In the Evaluation of Persistent Febrile Neutropenia in Cancer Patients
- Fatigue and Symptom Burden in Febrile Neutropenia
- A Pilot Study to Evaluate the Safety and Activities of EW02 in Reducing Neutropenia Caused by Chemotherapy
- Safety and Effectiveness of Granulocyte Transfusions in Resolving Infection in People With Neutropenia (The RING Study)
National Guidelines Clearinghouse
- 2006 update of recommendations for the use of white blood cell growth factors: an evidence-based clinical practice guideline. American Society of Clinical Oncology - Medical Specialty Society. 1994 Nov (revised 2006 Jul 1). 19 pages. NGC:005040
- Clinical guideline on dental management of pediatric patients receiving chemotherapy, hematopoietic cell transplantation, and/or radiation. American Academy of Pediatric Dentistry - Professional Association. 2004. 6 pages. [NGC Update Pending] NGC:004039
Keywords
granulocytopenia, neutropenia, agranulocytosis, granulopenia, leukopenia, hypogranulocytosis, neutrophils, eosinophils, basophils, granulocytes, granulocyte colony-stimulating factor, GCSF, granulocyte-macrophage colony-stimulating factor, GM-CSF
Follow-up: Granulocytopenia