Acute Otitis Media Organism-Specific Therapy 

Updated: Dec 17, 2015
  • Author: Brenda L Natal, MD, MPH; Chief Editor: Thomas E Herchline, MD  more...
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Specific Organisms and Therapeutic Regimens

Organism-specific therapeutic regimens for acute otitis media in adults are outlined below, including those for Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis. [1, 2, 3, 4, 5]

Streptococcus pneumoniae

See the list below:

Haemophilus influenzae

See the list below:

  • Amoxicillin-clavulanate 875 mg/125 mg PO BID for 7-10d or
  • Cefuroxime 500 mg PO BID for 7-14d or
  • Cefpodoxime 200 mg PO BID for 7-10d or
  • Cefprozil 250-500 mg PO BID for 10d or
  • Ceftriaxone 1 g IM every other day for 3 doses

Moraxella catarrhalis

See the list below:

  • Amoxicillin-clavulanate 875 mg/125 mg PO BID for 7-10d or
  • Cefuroxime 500 mg PO BID for 7-14d or
  • Cefpodoxime 200 mg PO BID for 7-10d or
  • Cefprozil 250-500 mg PO BID for 10d or
  • Ceftriaxone 1 g IM every other day for 3 doses