Dental Abscess Empiric Therapy 

Updated: Mar 03, 2015
  • Author: Jane M Gould, MD, FAAP; Chief Editor: Thomas E Herchline, MD  more...
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Empiric Therapy Regimens

Most dental abscesses respond to surgical treatment (incision and drainage, root canal, or extraction) and elimination of the source of infection. The addition of antibiotics is not recommended for a localized dental abscess. Antibiotics are indicated if drainage is not possible or if the patient shows signs of systemic involvement or is immunocompromised. The duration of therapy should be 7d. [1, 2, 3, 4, 5]

Treatment recommendations

See the list below:

  • Penicillin VK 500mg PO TID or
  • Penicillin G 2-4 million U IV/IM q4-6h or
  • Amoxicillin-clavulanate 500mg/125mg PO TID or 875mg/125mg PO BID or
  • Clindamycin 300-450mg PO TID-QID or 600-900mg IV q6-8h
  • Duration of therapy: 7d