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Mucosa-Associated Lymphoid Tissue Differential Diagnoses

  • Author: Sara J Grethlein, MD; Chief Editor: Emmanuel C Besa, MD  more...
 
Updated: Dec 09, 2014
 
 

Diagnostic Considerations

Failure to diagnose cancer is one of the most frequent reasons for medical malpractice actions. Accordingly, any suggestive symptoms should be thoroughly investigated. Ion the setting of a known cancer, failure to diagnose the correct subtype of lymphoma and subsequent use of treatment for another type of lymphoma or other malignancy that is not optimal therapy for mucosa-associated lymphoid tissue (MALT) lymphoma (MALToma) is a medicolegal hazard.

In addition to the conditions listed in the differential diagnosis, other problems to be considered include the following:

  • Extranodal lymphoma
  • Gastric lymphoma
  • Low-grade non-Hodgkin lymphoma (NHL)

Differential Diagnoses

 
 
Contributor Information and Disclosures
Author

Sara J Grethlein, MD Associate Dean for Undergraduate Medical Education, Indiana University School of Medicine

Sara J Grethlein, MD is a member of the following medical societies: Alpha Omega Alpha, American College of Physicians, American Society of Hematology, American Society of Clinical Oncology

Disclosure: Nothing to disclose.

Chief Editor

Emmanuel C Besa, MD Professor Emeritus, Department of Medicine, Division of Hematologic Malignancies and Hematopoietic Stem Cell Transplantation, Kimmel Cancer Center, Jefferson Medical College of Thomas Jefferson University

Emmanuel C Besa, MD is a member of the following medical societies: American Association for Cancer Education, American Society of Clinical Oncology, American College of Clinical Pharmacology, American Federation for Medical Research, American Society of Hematology, New York Academy of Sciences

Disclosure: Nothing to disclose.

Acknowledgements

Troy H Guthrie, Jr, MD Director of Cancer Institute, Baptist Medical Center

Troy H Guthrie, Jr, MD is a member of the following medical societies: American Federation for Medical Research, American Medical Association, American Society of Hematology, Florida Medical Association, Medical Association of Georgia, and Southern Medical Association

Disclosure: Nothing to disclose.

Jose A Perez Jr, MD, MBA, MSEd Residency Director, Internal Medicine Residency Program, Vice Chair of Education, Department of Medicine, Methodist Hospital; Associate Professor of Clinical Medicine, Weill Cornell Medical College

Jose A Perez Jr, MD, MBA, MSEd is a member of the following medical societies: American College of Physician Executives, American College of Physicians, Society of General Internal Medicine, and Society of Hospital Medicine

Disclosure: Nothing to disclose.

Karen Seiter, MD Professor, Department of Internal Medicine, Division of Oncology/Hematology, New York Medical College

Karen Seiter, MD is a member of the following medical societies: American Association for Cancer Research, American College of Physicians, and American Society of Hematology

Disclosure: Novartis Honoraria Speaking and teaching; Novartis Consulting fee Speaking and teaching; Eisai Honoraria Speaking and teaching; Celgene Honoraria Speaking and teaching

Francisco Talavera, PharmD, PhD Adjunct Assistant Professor, University of Nebraska Medical Center College of Pharmacy; Editor-in-Chief, Medscape Drug Reference

Disclosure: Medscape Salary Employment

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Low magnification micrograph of a lymphoepithelial lesion of the gastrointestinal tract in the setting of a primary gastrointestinal tract lymphoma. H&E stain. Colonic biopsy (descending colon). Lymphoepithelial lesions are strongly associated with mucosa-associated lymphoid tissue lymphomas (MALT lymphomas); however, they may appear in other types of lymphomas.
High magnification micrograph of a lymphoepithelial lesion of the gastrointestinal tract in the setting of a primary gastrointestinal tract lymphoma. H&E stain. Colonic biopsy (descending colon). Lymphoepithelial lesions are strongly associated with mucosa-associated lymphoid tissue lymphomas (MALT lymphomas); however, they may appear in other types of lymphomas.
 
 
 
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