eMedicine Specialties > Infectious Diseases > Skin and Soft-Tissue Infections
Catscratch Disease: Follow-up
Updated: Jan 26, 2009
Follow-up
Further Inpatient Care
- Depending on severity, immunocompromised patients or patients with atypical manifestations of catscratch disease (CSD) may require hospitalization.
Further Outpatient Care
- Patients should be instructed to return for a follow-up evaluation to ensure resolution of lymphadenopathy in 2-4 months.
- Patients should return to care if their condition worsens or the lymph node starts to suppurate.
Prognosis
- Catscratch disease is usually self-limiting and carries an excellent prognosis.
- Complications and sequelae are rare in typical catscratch disease.
- Severe encephalitis and other disseminated forms of B henselae infection can lead to long-term sequelae.
- The disease is very rare.
Miscellaneous
Medicolegal Pitfalls
- Symptoms of catscratch disease (CSD) that do not resolve and persistent lymphadenopathy should be re-evaluated for other infectious etiologies and lymphoma.
- Failure to have the patient follow up for resolution of symptoms and to rule out other etiologies may result in adverse outcomes.
- If antibiotics are administered, monitor for adverse reactions. Dose adjustments may be necessary in children and in cases of renal insufficiency and hepatic disease.
More on Catscratch Disease |
| Overview: Catscratch Disease |
| Differential Diagnoses & Workup: Catscratch Disease |
| Treatment & Medication: Catscratch Disease |
Follow-up: Catscratch Disease |
| References |
| « Previous Page |
References
Reynolds MG, Holman RC, Curns AT, O'Reilly M, McQuiston JH, Steiner CA. Epidemiology of cat-scratch disease hospitalizations among children in the United States. Pediatr Infect Dis J. Aug 2005;24(8):700-4. [Medline].
Jackson LA, Perkins BA, Wenger JD. Cat scratch disease in the United States: an analysis of three national databases. Am J Public Health. Dec 1993;83(12):1707-11. [Medline].
Dolan MJ, Wong MT, Regnery RL, Jorgensen JH, Garcia M, Peters J. Syndrome of Rochalimaea henselae adenitis suggesting cat scratch disease. Ann Intern Med. Mar 1 1993;118(5):331-6. [Medline].
Florin TA, Zaoutis TE, Zaoutis LB. Beyond cat scratch disease: widening spectrum of Bartonella henselae infection. Pediatrics. May 2008;121(5):e1413-25. [Medline].
Bass JW, Freitas BC, Freitas AD, et al. Prospective randomized double blind placebo-controlled evaluation of azithromycin for treatment of cat-scratch disease. Pediatr Infect Dis J. Jun 1998;17(6):447-52. [Medline].
Musso D, Drancourt M, Raoult D. Lack of bactericidal effect of antibiotics except aminoglycosides on Bartonella (Rochalimaea) henselae. J Antimicrob Chemother. Jul 1995;36(1):101-8. [Medline].
Ives TJ, Manzewitsch P, Regnery RL, Butts JD, Kebede M. In vitro susceptibilities of Bartonella henselae, B. quintana, B. elizabethae, Rickettsia rickettsii, R. conorii, R. akari, and R. prowazekii to macrolide antibiotics as determined by immunofluorescent-antibody analysis of infected Vero cell monolayers. Antimicrob Agents Chemother. Mar 1997;41(3):578-82. [Medline].
Adal KA, Cockerell CJ, Petri WA Jr. Cat scratch disease, bacillary angiomatosis, and other infections due to Rochalimaea. N Engl J Med. May 26 1994;330(21):1509-15. [Medline].
Baorto E, Payne RM, Slater LN, et al. Culture-negative endocarditis caused by Bartonella henselae. J Pediatr. Jun 1998;132(6):1051-4. [Medline].
Bass JW, Vincent JM, Person DA. The expanding spectrum of Bartonella infections: II. Cat-scratch disease. Pediatr Infect Dis J. Feb 1997;16(2):163-79. [Medline].
Batts S, Demers DM. Spectrum and treatment of cat-scratch disease. Pediatr Infect Dis J. Dec 2004;23(12):1161-2. [Medline].
Ben-Ami R, Ephros M, Avidor B, Katchman E, Varon M, Leibowitz C. Cat-scratch disease in elderly patients. Clin Infect Dis. Oct 1 2005;41(7):969-74. [Medline].
Carithers HA. Cat-scratch disease: an overview based on a study of 1200 patients. Am J Dis Child. 1985;139:1124-33. [Medline].
Chia JK, Nakata MM, Lami JL, et al. Azithromycin for the treatment of cat-scratch disease. Clin Infect Dis. Jan 1998;26(1):193-4. [Medline].
Cunha BA. Antibiotic Essentials. 5th ed. Royal Oak, Mich: Physicians Press; 2006.
Dyachenko P, Ziv M, Raz R, Chazan B, Lev A, Rozenman D. Cat scratch disease encephalopathy in an immunocompetent patient. Eur J Intern Med. Dec 2005;16(8):610-1. [Medline].
Giladi M, Maman E, Paran D, Bickels J, Comaneshter D, Avidor B. Cat-scratch disease-associated arthropathy. Arthritis Rheum. Nov 2005;52(11):3611-7. [Medline].
Grando D, Sullivan LJ, Flexman JP, Watson MW, Andrew JH. Bartonella henselae associated with Parinaud's oculoglandular syndrome. Clin Infect Dis. May 1999;28(5):1156-8. [Medline].
Lamps LW, Scott MA. Cat-scratch disease: historic, clinical, and pathologic perspectives. Am J Clin Pathol. Jun 2004;121 Suppl:S71-80. [Medline].
Losanoff JE, Sauter ER, Rider KD. Cat scratch disease presenting with abdominal pain and retroperitoneal lymphadenopathy. J Clin Gastroenterol. Mar 2004;38(3):300-1. [Medline].
Margileth AM. Antibiotic therapy for cat-scratch disease: clinical study of therapeutic outcome in 268 patients and a review of the literature. Pediatr Infect Dis J. Jun 1992;11(6):474-8. [Medline].
Margileth AM. Recent Advances in Diagnosis and Treatment of Cat Scratch Disease. Curr Infect Dis Rep. Apr 2000;2(2):141-146. [Medline].
Martínez-Osorio H, Calonge M, Torres J, González F. Cat-scratch disease (ocular bartonellosis) presenting as bilateral recurrent iridocyclitis. Clin Infect Dis. Mar 1 2005;40(5):e43-5. [Medline].
Massei F, Gori L, Macchia P, Maggiore G. The expanded spectrum of bartonellosis in children. Infect Dis Clin North Am. Sep 2005;19(3):691-711. [Medline].
Noyola DE, Holder DL, Fishman MA, Edwards MS. Recurrent encephalopathy in cat-scratch disease. Pediatr Infect Dis J. Jun 1999;18(6):567-8. [Medline].
Reed JB, Scales DK, Wong MT, et al. Bartonella henselae neuroretinitis in cat scratch disease. Diagnosis, management, and sequelae. Ophthalmology. Mar 1998;105(3):459-66. [Medline].
Robson JM, Harte GJ, Osborne DR, et al. Cat-scratch disease with paravertebral mass and osteomyelitis. Clin Infect Dis. Feb 1999;28(2):274-8. [Medline].
Rolain JM, Brouqui P, Koehler JE, Maguina C, Dolan MJ, Raoult D. Recommendations for treatment of human infections caused by Bartonella species. Antimicrob Agents Chemother. Jun 2004;48(6):1921-33. [Medline].
Schmalfuss IM, Dean CW, Sistrom C, Bhatti MT. Optic neuropathy secondary to cat scratch disease: distinguishing MR imaging features from other types of optic neuropathies. AJNR Am J Neuroradiol. Jun-Jul 2005;26(6):1310-6. [Medline].
Seals JE, Oken HA. Cat scratch encephalopathy. Md Med J. Jul-Aug 1999;48(4):176-8. [Medline].
Tsujino K, Tsukahara M, Tsuneoka H, Ichihara K, Furuya T, Kawauchi S. Clinical implication of prolonged fever in children with cat scratch disease. J Infect Chemother. Aug 2004;10(4):227-33. [Medline].
Zangwill K. Therapeutic options for cat-scratch disease. Pediatr Infect Dis J. Nov 1998;17(11):1059-61. [Medline].
Further Reading
Keywords
catscratch disease, cat scratch disease, CSD, cat scratch fever, catscratch fever, Bartonella henselae infection, B henselae infection, Bartonella infection, bacillary angiomatosis, peliosis, verruga peruana, Parinaud's oculoglandular syndrome, Parinaud oculoglandular syndrome, Parinaud syndrome, neuroretinitis, acute encephalopathy, endocarditis, Bartonella endocarditis, subacute regional lymphadenitis, bartonellosis, catscratch antigen, CSA, atypical catscratch disease, atypical cat scratch disease, Rochalimaea henselae, R henselae
Follow-up: Catscratch Disease