eMedicine Specialties > Infectious Diseases > Viral Infections

Cytomegalovirus: Multimedia

Author: Todd S Wills, MD, Assistant Professor, Department of Internal Medicine, Division of Infectious Diseases, University of South Florida College of Medicine
Contributor Information and Disclosures

Updated: Apr 28, 2009

Multimedia

Here, using immunofluorescent technique, a specim...Media file 1: Here, using immunofluorescent technique, a specimen of human embryonic lung (25X) reveals the presence of cytomegalovirus. Courtesy of the CDC/Dr. Craig Lyerla.
Here, using immunofluorescent technique, a specim...

Here, using immunofluorescent technique, a specimen of human embryonic lung (25X) reveals the presence of cytomegalovirus. Courtesy of the CDC/Dr. Craig Lyerla.

More on Cytomegalovirus

Overview: Cytomegalovirus
Differential Diagnoses & Workup: Cytomegalovirus
Treatment & Medication: Cytomegalovirus
Follow-up: Cytomegalovirus
Multimedia: Cytomegalovirus
References

References

  1. [Best Evidence] Pass RF, Zhang C, Evans A, Simpson T, Andrews W, Huang ML, et al. Vaccine prevention of maternal cytomegalovirus infection. N Engl J Med. Mar 19 2009;360(12):1191-9. [Medline].

  2. Afessa B, Peters SG. Major complications following hematopoietic stem cell transplantation. Semin Respir Crit Care Med. Jun 2006;27(3):297-309.

  3. Berenberg W, Nankervis G. Long-term follow-up of cytomegalic inclusion disease of infancy. Pediatrics. Sep 1970;46(3):403-10. [Medline].

  4. Boeckh M, Gooley TA, Myerson D. Cytomegalovirus pp65 antigenemia-guided early treatment with ganciclovir versus ganciclovir at engraftment after allogeneic marrow transplantation: a randomized double-blind study. Blood. Nov 15 1996;88(10):4063-71. [Medline].

  5. Bonkowsky HL, Lee RV, Klatskin G. Acute granulomatous hepatitis. Occurrence in cytomegalovirus mononucleosis. JAMA. Sep 22 1975;233(12):1284-8. [Medline].

  6. Boppana SB, Pass RF, Britt WJ. Symptomatic congenital cytomegalovirus infection: neonatal morbidity and mortality. Pediatr Infect Dis J. Feb 1992;11(2):93-9. [Medline].

  7. Britt W, Alford C. Cytomegalovirus. In: Virology. Philadelphia, Pa: Lippincott Raven; 1996:. 2493-545.

  8. Cohen BA. Prognosis and response to therapy of cytomegalovirus encephalitis and meningomyelitis in AIDS. Neurology. Feb 1996;46(2):444-50. [Medline].

  9. Dieterich DT, Chachoua A, Lafleur F. Ganciclovir treatment of gastrointestinal infections caused by cytomegalovirus in patients with AIDS. Rev Infect Dis. Jul-Aug 1988;10 Suppl 3:S532-7. [Medline].

  10. Dieterich DT, Rahmin M. Cytomegalovirus colitis in AIDS: presentation in 44 patients and a review of the literature. J Acquir Immune Defic Syndr. 1991;4 Suppl 1:S29-35. [Medline].

  11. Falagas ME, Vardakas KZ. Anti-cytomegalovirus prophylaxis in solid-organ transplant recipients. Clin Microbiol Infect. Jul 2006;12(7):603-5.

  12. Gershon A, Gold E, Nankervis G. Viral Infections of Humans. 4th ed. New York, NY: Plenum Medical; 1997:. 229-51.

  13. Goodrich J, Khardori N. Cytomegalovirus: the taming of the beast?. Lancet. Dec 13 1997;350(9093):1718-9. [Medline].

  14. Goodrich JM, Bowden RA, Fisher L. Ganciclovir prophylaxis to prevent cytomegalovirus disease after allogeneic marrow transplant. Ann Intern Med. Feb 1 1993;118(3):173-8. [Medline].

  15. Griffiths P, Emery V. Cytomegalovirus. In: Clinical Virology. New York, NY: Churchill Livingstone; 1997:. 445-70.

  16. Horwitz CA, Henle W, Henle G. Clinical and laboratory evaluation of cytomegalovirus-induced mononucleosis in previously healthy individuals. Report of 82 cases. Medicine (Baltimore). Mar 1986;65(2):124-34. [Medline].

  17. Khoury JA, Storch GA, Bohl DL, et al. Prophylactic Versus Preemptive Oral Valganciclovir for the Management of Cytomegalovirus Infection in Adult Renal Transplant Recipients. Am J Transplant. Jun 19 2006.

  18. Li CR, Greenberg PD, Gilbert MJ. Recovery of HLA-restricted cytomegalovirus (CMV)-specific T-cell responses after allogeneic bone marrow transplant: correlation with CMV disease and effect of ganciclovir prophylaxis. Blood. Apr 1 1994;83(7):1971-9. [Medline].

  19. Limaye AP, Bakthavatsalam R, Kim HW, et al. Impact of cytomegalovirus in organ transplant recipients in the era of antiviral prophylaxis. Transplantation. Jun 27 2006;81(12):1645-52.

  20. McCutchan JA. Cytomegalovirus infections of the nervous system in patients with AIDS. Clin Infect Dis. Apr 1995;20(4):747-54. [Medline].

  21. Meiselman MS, Cello JP, Margaretten W. Cytomegalovirus colitis. Report of the clinical, endoscopic, and pathologic findings in two patients with the acquired immune deficiency syndrome. Gastroenterology. Jan 1985;88(1 Pt 1):171-5. [Medline].

  22. Reed EC, Bowden RA, Dandliker PS. Treatment of cytomegalovirus pneumonia with ganciclovir and intravenous cytomegalovirus immunoglobulin in patients with bone marrow transplants. Ann Intern Med. Nov 15 1988;109(10):783-8. [Medline].

  23. Richardson WP, Colvin RB, Cheeseman SH. Glomerulopathy associated with cytomegalovirus viremia in renal allografts. N Engl J Med. Jul 9 1981;305(2):57-63. [Medline].

  24. Riddell SR, Watanabe KS, Goodrich JM. Restoration of viral immunity in immunodeficient humans by the adoptive transfer of T cell clones. Science. Jul 10 1992;257(5067):238-41. [Medline].

  25. Snover D, Hutton S, Bloomer J. Cytomegalovirus hepatitis: A histological and immunochemical comparison in immunocompromised and immunocompetent patients. Laboratory Investigation. 1985;52:6 A.

  26. Snover DC, Horwitz CA. Liver disease in cytomegalovirus mononucleosis: a light microscopical and immunoperoxidase study of six cases. Hepatology. May-Jun 1984;4(3):408-12. [Medline].

  27. Thorne JE, Jabs DA, Kempen JH, et al. Causes of visual acuity loss among patients with AIDS and cytomegalovirus retinitis in the era of highly active antiretroviral therapy. Ophthalmology. Aug 2006;113(8):1441-5.

  28. Torok-Storb B, Boeckh M, Hoy C. Association of specific cytomegalovirus genotypes with death from myelosuppression after marrow transplantation. Blood. Sep 1 1997;90(5):2097-102. [Medline].

  29. Walter EA, Greenberg PD, Gilbert MJ. Reconstitution of cellular immunity against cytomegalovirus in recipients of allogeneic bone marrow by transfer of T-cell clones from the donor. N Engl J Med. Oct 19 1995;333(16):1038-44. [Medline].

  30. Whimbey E, Champlin RE, Couch RB. Community respiratory virus infections among hospitalized adult bone marrow transplant recipients. Clin Infect Dis. May 1996;22(5):778-82. [Medline].

  31. Wilcox CM, Diehl DL, Cello JP. Cytomegalovirus esophagitis in patients with AIDS. A clinical, endoscopic, and pathologic correlation. Ann Intern Med. Oct 15 1990;113(8):589-93. [Medline].

Further Reading

Keywords

cytomegalovirus, CMV, Betaherpesvirinae, Herpesviridae, mononucleosis, pneumonia, hepatitis, encephalitis, colitis, uveitis, retinitis, neuropathy, HIV, CMV syndrome, fever of unknown origin, FUO, STDs, transplant infections

Contributor Information and Disclosures

Author

Todd S Wills, MD, Assistant Professor, Department of Internal Medicine, Division of Infectious Diseases, University of South Florida College of Medicine
Todd S Wills, MD is a member of the following medical societies: Infectious Diseases Society of America
Disclosure: Nothing to disclose.

Medical Editor

Douglas A Drevets, MD, Assistant Professor, Department of Medicine, Section of Infectious Disease, Oklahoma University Health Sciences Center
Douglas A Drevets, MD is a member of the following medical societies: American Association of Immunologists, American Society for Microbiology, Central Society for Clinical Research, and Christian Medical & Dental Society
Disclosure: Nothing to disclose.

Pharmacy Editor

Francisco Talavera, PharmD, PhD, Senior Pharmacy Editor, eMedicine
Disclosure: Nothing to disclose.

Managing Editor

John W King, MD, Professor of Medicine, Section of Infectious Diseases, Louisiana State University Health Sciences Center; Director, Viral Therapeutics Clinics for Hepatitis; Consulting Staff, Department of Infectious Diseases, Overton Brook Veterans Affairs Medical Center
John W King, MD is a member of the following medical societies: American Association for the Advancement of Science, American College of Physicians, American Federation for Medical Research, American Society for Microbiology, Association of Subspecialty Professors, Infectious Diseases Society of America, and Sigma Xi
Disclosure: emedicine $50.00 author of chapter

CME Editor

Eleftherios Mylonakis, MD, Clinical and Research Fellow, Department of Internal Medicine, Division of Infectious Diseases, Massachusetts General Hospital
Eleftherios Mylonakis, MD is a member of the following medical societies: American Association for the Advancement of Science, American College of Physicians, American Society for Microbiology, and Infectious Diseases Society of America
Disclosure: Nothing to disclose.

Chief Editor

Burke A Cunha, MD, Professor of Medicine, State University of New York School of Medicine at Stony Brook; Chief, Infectious Disease Division, Winthrop-University Hospital
Burke A Cunha, MD is a member of the following medical societies: American College of Chest Physicians, American College of Physicians, and Infectious Diseases Society of America
Disclosure: Nothing to disclose.

 
 
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