Ebola Virus: Multimedia

References

1. Sanchez A, Trappier SG, Mahy BW, Peters CJ, Nichol ST. The virion glycoproteins of Ebola viruses are encoded in two reading frames and are expressed through transcriptional editing. Proc Natl Acad Sci U S A. Apr 16 1996;93(8):3602-7. [Medline].

2. Leroy EM, Baize S, Volchkov VE, Fisher-Hoch SP, Georges-Courbot MC, Lansoud-Soukate J, et al. Human asymptomatic Ebola infection and strong inflammatory response. Lancet. Jun 24 2000;355(9222):2210-5. [Medline].

3. Amblard J, Obiang P, Edzang S, Prehaud C, Bouloy M, Guenno BL. Identification of the Ebola virus in Gabon in 1994. Lancet. Jan 18 1997;349(9046):181-2. [Medline].

4. Swanepoel R, Leman PA, Burt FJ, Zachariades NA, Braack LE, Ksiazek TG, et al. Experimental inoculation of plants and animals with Ebola virus. Emerg Infect Dis. Oct-Dec 1996;2(4):321-5. [Medline].

5. Johnson E, Jaax N, White J, Jahrling P. Lethal experimental infections of rhesus monkeys by aerosolized Ebola virus. Int J Exp Pathol. Aug 1995;76(4):227-36. [Medline].

6. Allela L, Boury O, Pouillot R, Delicat A, Yaba P, Kumulungui B, et al. Ebola virus antibody prevalence in dogs and human risk. Emerg Infect Dis. Mar 2005;11(3):385-90. [Medline].

7. Alsop Z. Ebola outbreak in Uganda "atypical", say experts. Lancet. Dec 22 2007;370(9605):2085. [Medline].

8. Geisbert TW, Jahrling PB. Differentiation of filoviruses by electron microscopy. Virus Res. Dec 1995;39(2-3):129-50. [Medline].

9. Geisbert TW, Hensley LE, Jahrling PB, Larsen T, Geisbert JB, Paragas J, et al. Treatment of Ebola virus infection with a recombinant inhibitor of factor VIIa/tissue factor: a study in rhesus monkeys. Lancet. Dec 13 2003;362(9400):1953-8. [Medline].

10. Sullivan NJ, Sanchez A, Rollin PE, Yang ZY, Nabel GJ. Development of a preventive vaccine for Ebola virus infection in primates. Nature. Nov 30 2000;408(6812):605-9. [Medline].

11. Geisbert TW, Pushko P, Anderson K, Smith J, Davis KJ, Jahrling PB. Evaluation in nonhuman primates of vaccines against Ebola virus. Emerg Infect Dis. May 2002;8(5):503-7. [Medline].

12. Bausch DG, Feldmann H, Geisbert TW, Bray M, Sprecher AG, Boumandouki P. Outbreaks of filovirus hemorrhagic fever: time to refocus on the patient. J Infect Dis. Nov 15 2007;196 Suppl 2:S136-41. [Medline].

13. Bwaka MA, Bonnet MJ, Calain P, Colebunders R, De Roo A, Guimard Y, et al. Ebola hemorrhagic fever in Kikwit, Democratic Republic of the Congo: clinical observations in 103 patients. J Infect Dis. Feb 1999;179 Suppl 1:S1-7. [Medline].

14. Dowell SF. Ebola hemorrhagic fever: why were children spared?. Pediatr Infect Dis J. Mar 1996;15(3):189-91. [Medline].

15. Feldmann H, Klenk HD, Sanchez A. Molecular biology and evolution of filoviruses. Arch Virol Suppl. 1993;7:81-100. [Medline].

16. Feldmann H, Slenczka W, Klenk HD. Emerging and reemerging of filoviruses. Arch Virol Suppl. 1996;11:77-100. [Medline].

17. Formenty P, Leroy EM, Epelboin A, Libama F, Lenzi M, Sudeck H, et al. Detection of Ebola virus in oral fluid specimens during outbreaks of Ebola virus hemorrhagic fever in the Republic of Congo. Clin Infect Dis. Jun 1 2006;42(11):1521-6. [Medline].

18. Georges-Courbot MC, Lu CY, Lansoud-Soukate J, Leroy E, Baize S. Isolation and partial molecular characterisation of a strain of Ebola virus during a recent epidemic of viral haemorrhagic fever in Gabon. Lancet. Jan 18 1997;349(9046):181. [Medline].

19. Gonzalez JP, Pourrut X, Leroy E. Ebolavirus and other filoviruses. Curr Top Microbiol Immunol. 2007;315:363-87. [Medline].

20. Jaax NK, Davis KJ, Geisbert TJ, Vogel P, Jaax GP, Topper M, et al. Lethal experimental infection of rhesus monkeys with Ebola-Zaire (Mayinga) virus by the oral and conjunctival route of exposure. Arch Pathol Lab Med. Feb 1996;120(2):140-55. [Medline].

21. Jahrling PB, Geisbert TW, Dalgard DW, Johnson ED, Ksiazek TG, Hall WC, et al. Preliminary report: isolation of Ebola virus from monkeys imported to USA. Lancet. Mar 3 1990;335(8688):502-5. [Medline].

22. Kiley MP, Bowen ET, Eddy GA, Isaacson M, Johnson KM, McCormick JB, et al. Filoviridae: a taxonomic home for Marburg and Ebola viruses?. Intervirology. 1982;18(1-2):24-32. [Medline].

23. Legrand J, Grais RF, Boelle PY, Valleron AJ, Flahault A. Understanding the dynamics of Ebola epidemics. Epidemiol Infect. May 2007;135(4):610-21. [Medline].

24. Onyango CO, Opoka ML, Ksiazek TG, Formenty P, Ahmed A, Tukei PM. Laboratory diagnosis of Ebola hemorrhagic fever during an outbreak in Yambio, Sudan, 2004. J Infect Dis. Nov 15 2007;196 Suppl 2:S193-8. [Medline].

25. Peters CJ. Ebola and hantaviruses. FEMS Immunol Med Microbiol. Aug 1997;18(4):281-9. [Medline].

26. Peters CJ, Sanchez A, Feldmann A. Filoviruses as emerging pathogens. Semin Virol. 1994;5:147-54.

27. Peterson AT, Bauer JT, Mills JN. Ecologic and geographic distribution of filovirus disease. Emerg Infect Dis. Jan 2004;10(1):40-7. [Medline].

28. Professional journal. Viral haemorrhagic fever in imported monkeys. Wkly Epidemiol Rec. May 8 1992;67(19):142-3. [Medline].

29. Sanchez A, Kiley MP, Holloway BP, Auperin DD. Sequence analysis of the Ebola virus genome: organization, genetic elements, and comparison with the genome of Marburg virus. Virus Res. Sep 1993;29(3):215-40. [Medline].

30. Takada A, Kawaoka Y. Pathogenesis of Ebola virus infection: recent insights. Trends Microbiol. Jul 1998;6(7):258-9. [Medline].

31. Volchkov VE, Volchkova VA, Slenczka W, Klenk HD, Feldmann H. Release of viral glycoproteins during Ebola virus infection. Virology. May 25 1998;245(1):110-9. [Medline].

Further Reading

Keywords

Ebola virus, viral hemorrhagic fever syndrome, Arenaviridae, Bunyaviridae, Flaviviridae, Filoviridae, EBO-Z, Marburg virus, Ebola infection, Ebola virus Zaire, Ebola virus Sudan, EBO-S, African-derived Ebola virus, Ebola virus Côte-d'Ivoire, EBO-C, Ebola virus Reston, EBO-R

Contributor Information and Disclosures

Author

John W King, MD, Professor of Medicine, Section of Infectious Diseases, Louisiana State University Health Sciences Center; Director, Viral Therapeutics Clinics for Hepatitis; Consulting Staff, Department of Infectious Diseases, Overton Brook Veterans Affairs Medical Center
John W King, MD is a member of the following medical societies: American Association for the Advancement of Science, American College of Physicians, American Federation for Medical Research, American Society for Microbiology, Association of Subspecialty Professors, Infectious Diseases Society of America, and Sigma Xi
Disclosure: emedicine $50.00 author of chapter

Medical Editor

Martin J Wood, MD †, Former Consulting Staff, Department of Infection and Tropical Medicine, Birmingham Heartlands Hospital, UK
Martin J Wood, MD † is a member of the following medical societies: Alliance for the Prudent Use of Antibiotics, American Society for Microbiology, Infectious Diseases Society of America, International Society for Infectious Diseases, and Royal College of Physicians
Disclosure: Nothing to disclose.

Pharmacy Editor

Francisco Talavera, PharmD, PhD, Senior Pharmacy Editor, eMedicine
Disclosure: Nothing to disclose.

Managing Editor

Thomas M Kerkering, MD, Professor of Medicine and Microbiology, Department of Internal Medicine, Division of Infectious Disease, Brody School of Medicine at East Carolina University
Thomas M Kerkering, MD is a member of the following medical societies: Alpha Omega Alpha, American College of Physicians, American Public Health Association, American Society for Microbiology, American Society of Tropical Medicine and Hygiene, Infectious Diseases Society of America, Medical Society of Virginia, and Wilderness Medical Society
Disclosure: Nothing to disclose.

CME Editor

Eleftherios Mylonakis, MD, Clinical and Research Fellow, Department of Internal Medicine, Division of Infectious Diseases, Massachusetts General Hospital
Eleftherios Mylonakis, MD is a member of the following medical societies: American Association for the Advancement of Science, American College of Physicians, American Society for Microbiology, and Infectious Diseases Society of America
Disclosure: Nothing to disclose.

Chief Editor

Burke A Cunha, MD, Professor of Medicine, State University of New York School of Medicine at Stony Brook; Chief, Infectious Disease Division, Winthrop-University Hospital
Burke A Cunha, MD is a member of the following medical societies: American College of Chest Physicians, American College of Physicians, and Infectious Diseases Society of America
Disclosure: Nothing to disclose.