Controlled Substance Schedules 

Updated: May 15, 2014
  • Author: Abimbola Farinde, PharmD, PhD; more...
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Controlled Substance Schedules

Schedule I (CI)

  • Drugs not used medically
  • Not accepted as safe for use under medical supervision
  • High abuse potential
  • Possession and supply prohibited
  • Examples include cannabis, LSD, ecstasy, heroin, and lysergic acid [1, 2, 3, 4, 5]

Schedule II (CII)

  • Accepted medical use
  • High abuse potential
  • May lead to severe psychological or physical dependence
  • Examples include amphetamines, codeine, morphine, methamphetamines, and pentobarbital

Schedule III (CIII)

  • Accepted medical use
  • Less abuse potential than CII
  • May lead to moderate to low physical dependence or high psychological dependence
  • Examples include acetaminophen with codeine, anabolic steroids, glutethimide, methyprylon, and naloxone

Schedule IV (CIV)

Schedule V (CV)

  • Often available without a prescription
  • Less abuse potential than CIV
  • May be subject to state and local regulations
  • Examples include buprenorphine, Robitussin, pregabalin, and diphenoxylate