Benzodiazepine Equivalency Table 

Updated: Apr 28, 2017
  • Author: Abimbola Farinde, PharmD, PhD; more...
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Benzodiazepine Equivalency

Evidence-based information on benzodiazepine equivalency is limited, and different sources may disagree; hence the use of dose ranges in this table. Even so, the data listed in this table are estimates, and their use requires clinical judgement.

Particularly when tapering a dose, a very gradual reduction with attention to patient response is required. This is particularly the case for patients who have been taking benzodiazepines for an extended period of time. When escalating a dose, it is preferable to err on the side of caution, to avoid overshooting and causing respiratory depression.

Table 1. Benzodiazepine Equivalency [1, 2, 3, 4] (Open Table in a new window)

  Approximately Equivalent Oral Doses, mg Time to Peak Level, hours Half-life, hours
Alprazolam (Xanax) 0.5–1 1-2 12
Bromazepam (Lexotan)* 3–6 1-4 20
Chlordiazepoxide (Librium) 10–25 1-4 100
Clonazepam (Klonopin) 0.25–0.5 1-4 34
Clorazepate (Tranxene) 7.5–15 0.5-2 100
Diazepam (Valium) 5–10 1-2 100
Flurazepam (Dalmane) 15–30 0.5-1 100
Lorazepam (Ativan) 1–2 1-4 15
Nitrazepam (Mogadon)* 2.5–10 0.5-2 30
Oxazepam (Serax) 15–30 1-4 8
Quazepam (Doral) 10–20 1.5 25-41
Temazepam (Restoril) 10–20 2-3 11
Triazolam (Halcion) 0.25–0.5 1-2 2
*Not available in the United States