International Normalized Ratio (INR) Targets: Atrial Fibrillation and Flutter 

Updated: Dec 10, 2014
  • Author: Buck Christensen; Chief Editor: Buck Christensen  more...
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International Normalized Ratio (INR) Targets: Atrial Fibrillation and Flutter

The international normalized ratio (INR) recommendations below are per guidelines from the American College of Chest Physicians (2008). [1]

The INR target (range) is 2.5 (2.0-3.0) in all of the following circumstances:

  • Ischemic stroke, transient ischemic attack (TIA), or systemic embolism
  • Risk factors (age >75 years, hypertension, diabetes mellitus, decreased left ventricular systolic function, heart failure)
  • After open-heart surgery
  • Planned cardioversion
  • Emergency cardioversion

Duration of therapy

  • Ischemic stroke, TIA, or systemic embolism: Long-term
  • Risk factors: Long-term
  • Mitral stenosis: Long-term
  • After open-heart surgery: 4 weeks
  • Planned cardioversion: 3 weeks prior and 4 weeks after
  • Emergency cardioversion: 4 weeks