Hand-Foot-and-Mouth Disease (HFMD) Medication

Updated: Jun 16, 2017
  • Author: Stephen J Nervi, MD; Chief Editor: Michael Stuart Bronze, MD  more...
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Medication

Medication Summary

The goals of pharmacotherapy are to reduce morbidity and to prevent complications.

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Antipyretics/analgesics

Class Summary

These agents are used to control fever and pain.

Acetaminophen (Tylenol, Aspirin Free Anacin, Feverall)

Reduces fever by acting directly on hypothalamic heat-regulating centers, which increases dissipation of body heat via vasodilation and sweating.

Ibuprofen (Motrin, Ibuprin)

One of the few NSAIDs indicated for reduction of fever.

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Topical anesthetics

Class Summary

These agents can be applied to ulcerations to control pain.

Lidocaine anesthetic (Dermaflex)

Decreases permeability to sodium ions in neuronal membranes. This results in the inhibition of depolarization, blocking the transmission of nerve impulses.

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Antihistamines

Class Summary

These agents act by competitive inhibition of histamine at the H1 receptor.

Diphenhydramine hydrochloride (Benadryl, Benylin)

For symptomatic relief of symptoms caused by release of histamine in allergic reactions.

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