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Staphylococcal Infections Follow-up

  • Author: Thomas E Herchline, MD; Chief Editor: Mark R Wallace, MD, FACP, FIDSA  more...
 
Updated: Apr 25, 2016
 

Further Inpatient Care

Many hospitals have implemented screening for methicillin-resistant S aureus (MRSA) infections upon admission to an intensive care unit. Topical decolonization therapy and contact isolation of patients who test positive for MRSA has been shown to decrease MRSA infection rates.[17]

A nationwide Veterans Administration hospital program of nasal surveillance, contact precautions, and hand hygiene reduced ICU healthcare-associated MRSA infections by 62% and non-ICU healthcare-associated MRSA infections by 45%.[33]

Nonantibiotic methods to reduce nasal S aureus colonization are emerging. A study by Steed et al showed nasal application of a nonantibiotic alcohol-based antiseptic (Nozin Nasal Sanitizer advanced antiseptic from Global Life Technologies, Corp) was effective in reducing S aureus and total bacterial carriage, suggesting the usefulness of this approach as a safe, effective, and convenient alternative to antibiotic treatment. Seventy-eight of 387 healthcare providers screened (20.2%) tested positive for S aureus infection. Of 39 subjects who tested positive for S aureus infection who completed the study, 20 received antiseptic and 19 received placebo treatment. Antiseptic treatment reduced S aureus colony-forming units from baseline by 99% (median) and 82% (mean) (P < 0.001). Total bacterial colony-forming units were reduced by 91% (median) and 71% (mean) (P < 0.001).[34]

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Complications

Complications of S aureus bacteremia include septic arthritis, osteomyelitis, pyomyositis, endocarditis, and pneumonia.

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Prognosis

The prognosis of staphylococcal infections varies widely depending on the site of infection and the underlying condition. Overall, the prognosis is good, with full recovery in most patients who receive appropriate therapy.

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Patient Education

For excellent patient education resources, visit eMedicineHealth's Women's Health Center. Also, see eMedicineHealth's patient education article Toxic Shock Syndrome.

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Contributor Information and Disclosures
Author

Thomas E Herchline, MD Professor of Medicine, Wright State University, Boonshoft School of Medicine; Medical Director, Public Health, Dayton and Montgomery County, Ohio

Thomas E Herchline, MD is a member of the following medical societies: Alpha Omega Alpha, Infectious Diseases Society of Ohio, Infectious Diseases Society of America

Disclosure: Nothing to disclose.

Specialty Editor Board

Francisco Talavera, PharmD, PhD Adjunct Assistant Professor, University of Nebraska Medical Center College of Pharmacy; Editor-in-Chief, Medscape Drug Reference

Disclosure: Received salary from Medscape for employment. for: Medscape.

John L Brusch, MD, FACP Assistant Professor of Medicine, Harvard Medical School; Consulting Staff, Department of Medicine and Infectious Disease Service, Cambridge Health Alliance

John L Brusch, MD, FACP is a member of the following medical societies: American College of Physicians, Infectious Diseases Society of America

Disclosure: Nothing to disclose.

Chief Editor

Mark R Wallace, MD, FACP, FIDSA Clinical Professor of Medicine, Florida State University College of Medicine; Clinical Professor of Medicine, University of Central Florida College of Medicine

Mark R Wallace, MD, FACP, FIDSA is a member of the following medical societies: American College of Physicians, American Medical Association, American Society for Microbiology, Infectious Diseases Society of America, International AIDS Society, Florida Infectious Diseases Society

Disclosure: Nothing to disclose.

Additional Contributors

Klaus-Dieter Lessnau, MD, FCCP Clinical Associate Professor of Medicine, New York University School of Medicine; Medical Director, Pulmonary Physiology Laboratory; Director of Research in Pulmonary Medicine, Department of Medicine, Section of Pulmonary Medicine, Lenox Hill Hospital

Klaus-Dieter Lessnau, MD, FCCP is a member of the following medical societies: American College of Chest Physicians, American College of Physicians, American Medical Association, American Thoracic Society, Society of Critical Care Medicine

Disclosure: Nothing to disclose.

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