eMedicine Specialties > Nephrology > Glomerular Diseases

Glomerulonephritis, Nonstreptococcal Associated With Infection: Follow-up

Author: James W Lohr, MD, Fellowship Program Director, Professor, Department of Internal Medicine, Division of Nephrology, State University of New York at Buffalo
Coauthor(s): Quresh T Khairullah, MBBS, Consulting Staff, Department of Medicine, Division of Nephrology, St John's Hospital and Medical Center
Contributor Information and Disclosures

Updated: Dec 15, 2008

Follow-up

Further Inpatient Care

  • Inpatient care depends on the severity of infection, and the need for hospitalization depends on the clinical condition of the patient (eg, the patient may require dialytic support or IV fluids and antibiotics).

Further Outpatient Care

  • Oral antibiotics can be continued in an outpatient setting, with frequent monitoring of kidney function. Outpatient dialysis, if necessary, may need to be arranged.

Inpatient & Outpatient Medications

  • Oral antibiotics can be continued in an outpatient setting.

Complications

  • Deterioration of kidney function may require dialytic support.

Prognosis

  • Complete recovery occurs in most patients, even those patients with crescents observed in kidney biopsy tissue.
  • The outcome is based on the duration of infection before specific antibacterial or other antiinfective therapy is initiated.
  • In schistosomal infections, progression of renal disease is common, even after treatment.
  • Nephrotic-range proteinuria may persist for 6 months. A mild increase in protein excretion may be present in 15% of patients at 3 years and in 2-7% of patients at 10 years.
  • Microscopic hematuria may persist for 3-6 months after resolution of the syndrome.

Patient Education

Miscellaneous

Medicolegal Pitfalls

  • Failure to accurately diagnose
 


More on Glomerulonephritis, Nonstreptococcal Associated With Infection

Overview: Glomerulonephritis, Nonstreptococcal Associated With Infection
Differential Diagnoses & Workup: Glomerulonephritis, Nonstreptococcal Associated With Infection
Treatment & Medication: Glomerulonephritis, Nonstreptococcal Associated With Infection
Follow-up: Glomerulonephritis, Nonstreptococcal Associated With Infection
References

References

  1. Appel G. Viral infections and the kidney: HIV, hepatitis B, and hepatitis C. Cleve Clin J Med. May 2007;74(5):353-60. [Medline].

  2. Atta MG, Gallant JE, Rahman MH, et al. Antiretroviral therapy in the treatment of HIV-associated nephropathy. Nephrol Dial Transplant. Oct 2006;21(10):2809-13. [Medline].

  3. Barsoum R. The changing face of schistosomal glomerulopathy. Kidney Int. Dec 2004;66(6):2472-84. [Medline].

  4. Chadban SJ, Atkins RC. Glomerulonephritis. Lancet. May 21-27 2005;365(9473):1797-806. [Medline].

  5. Conlon PJ, Jefferies F, Krigman HR, et al. Predictors of prognosis and risk of acute renal failure in bacterial endocarditis. Clin Nephrol. Feb 1998;49(2):96-101. [Medline].

  6. Haffner D, Schindera F, Aschoff A, et al. The clinical spectrum of shunt nephritis. Nephrol Dial Transplant. Jun 1997;12(6):1143-8. [Medline].

  7. Jefferson JA, Johnson RJ. Treatment of hepatitis C-associated glomerular disease. Semin Nephrol. May 2000;20(3):286-92. [Medline].

  8. Kamar N, Izopet J, Alric L, et al. Hepatitis C virus-related kidney disease: an overview. Clin Nephrol. Mar 2008;69(3):149-60. [Medline].

  9. Lu TC, Ross M. HIV-associated nephropathy: a brief review. Mt Sinai J Med. May 2005;72(3):193-9. [Medline].

  10. Sorger K. Postinfectious glomerulonephritis. Subtypes, clinico-pathological correlations, and follow-up studies. Veroff Pathol. 1986;125:1-105. [Medline].

  11. Tang S, Lai FM, Lui YH, et al. Lamivudine in hepatitis B-associated membranous nephropathy. Kidney Int. Oct 2005;68(4):1750-8. [Medline].

  12. Wyatt CM, Rosenstiel PE, Klotman PE. HIV-associated nephropathy. Contrib Nephrol. 2008;159:151-61. [Medline].

Further Reading

Keywords

glomerular diseases associated with infection, glomerular disease, infection-related glomerulonephritis, GN, postinfectious glomerulonephritis, PIGN, bacterial infection, viral infection, protozoal infection, helminth infection, bacterial endocarditis, shunt nephritis, visceral abscesses, syphilis, hepatitis B, hepatitis C, human immunodeficiency virus, HIV, cytomegalovirus, CMV, parvovirus B19, Hantavirus, malaria, schistosomiasis, leishmaniasis, filariasis, hydatid disease, toxoplasmosis, aspergillosis

Contributor Information and Disclosures

Author

James W Lohr, MD, Fellowship Program Director, Professor, Department of Internal Medicine, Division of Nephrology, State University of New York at Buffalo
James W Lohr, MD is a member of the following medical societies: American College of Physicians, American Heart Association, American Society of Nephrology, and Central Society for Clinical Research
Disclosure: Nothing to disclose.

Coauthor(s)

Quresh T Khairullah, MBBS, Consulting Staff, Department of Medicine, Division of Nephrology, St John's Hospital and Medical Center
Quresh T Khairullah, MBBS is a member of the following medical societies: American College of Physicians, American Society of Nephrology, and International Society of Nephrology
Disclosure: Nothing to disclose.

Medical Editor

Frank C Brosius III, MD, Nephrology Program Director, Department of Internal Medicine, Division of Nephrology, Professor of Internal Medicine and Physiology, University of Michigan School of Medicine
Frank C Brosius III, MD is a member of the following medical societies: Alpha Omega Alpha, American Diabetes Association, American Society of Nephrology, and Phi Beta Kappa
Disclosure: Nothing to disclose.

Pharmacy Editor

Francisco Talavera, PharmD, PhD, Senior Pharmacy Editor, eMedicine
Disclosure: Nothing to disclose.

Managing Editor

Ajay K Singh, MB, MRCP, MBA, Associate Professor of Medicine, Director of Dialysis, Department of Medicine, Harvard Medical School; Clinical Chief of Renal Division, Brigham and Women's Hospital
Disclosure: Nothing to disclose.

CME Editor

Rebecca J Schmidt, DO, FACP, FASN, Professor of Medicine, Section Chief, Department of Medicine, Section of Nephrology, West Virginia University School of Medicine
Rebecca J Schmidt, DO, FACP, FASN is a member of the following medical societies: American College of Osteopathic Internists, American College of Physicians, American Medical Association, American Society of Nephrology, International Society of Nephrology, National Kidney Foundation, Renal Physicians Association, and West Virginia State Medical Association
Disclosure: Abbott Grant/research funds Speaking and teaching; Genzyme Honoraria Consulting; Roche Honoraria Consulting

Chief Editor

Vecihi Batuman, MD, FACP, FASN, Professor of Medicine, Section of Nephrology-Hypertension, Tulane University School of Medicine; Chief, Medicine Service, Southeast Louisiana Veterans Health Care System
Vecihi Batuman, MD, FACP, FASN is a member of the following medical societies: American College of Physicians, American Society of Hypertension, American Society of Nephrology, and International Society of Nephrology
Disclosure: Nothing to disclose.

 
 
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