Outcome and Prognosis
In general, outcome is good. A typical patient should return to baseline after shunting, unless prolonged elevated intracranial pressure or brain herniation has occurred. The neurologic function of children is optimized with shunting. Infection, especially if repeated, may affect cognitive status.
The best long-term results in the most carefully selected patients are no better than 60% in normal pressure hydrocephalus. Few complete recoveries occur. Often, gait and incontinence respond to shunting, but dementia responds less frequently.
Often, various other neurologic abnormalities associated with hydrocephalus are the limiting factor in patient recovery. Examples are migrational abnormalities and postinfectious hydrocephalus.
Future and Controversies
Hydrocephalus research and treatment have advanced tremendously in the last 20 years. Examples are the development of new shunt materials and, more recently, programmable valve technology. Current research categories include the following:
- Transplantation of tissue, such as vascularized omentum, to reestablish normal cerebrospinal fluid (CSF) could be the best method to treat communicating hydrocephalus.
- Third ventriculostomies and aqueductoplasty eliminate the need for shunting in noncommunicating cases of hydrocephalus. New optics and smaller scopes have expanded this field over the last 5 years.
The author would like to thank Dr. Yoon Hahn and Dr. David McLone for their guidance in treating patients with hydrocephalus.
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References
Hahn YS, Engelhard H, McLone DG. Abdominal CSF pseudocyst. Clinical features and surgical management. Pediatr Neurosci. 1985-1986;12(2):75-9. [Medline].
Aronyk KE. The history and classification of hydrocephalus. Neurosurg Clin N Am. Oct 1993;4(4):599-609. [Medline].
Black PMcL, Ojemann RG. Hydrocephalus in adults. In: Youman JR, ed. Neurological Surgery. 3rd ed. Philadelphia, Pa:. WB Saunders Co;1990:927-944.
Gleason PL, Black PM, Matsumae M. The neurobiology of normal pressure hydrocephalus. Neurosurg Clin N Am. Oct 1993;4(4):667-75. [Medline].
McLone DG, Partington MD. Arrest and compensation of hydrocephalus. Neurosurg Clin N Am. Oct 1993;4(4):621-4. [Medline].
Milhorat T. Hydrocephalus: Pathophysiology and Clinical Features. Neurosurgery. 1996;3:3625-3632.
Pang D, Altschuler E. Low-pressure hydrocephalic state and viscoelastic alterations in the brain. Neurosurgery. Oct 1994;35(4):643-55; discussion 655-6. [Medline].
Sainte-Rose C. Hydrocephalus in childhood.In: Youmans JR, ed. Neurological Surgery. Philadelphia, Pa:. WB Saunders Co;1996:890-926.
Further Reading
Keywords
hydrocephalus, abnormal rise in cerebrospinal fluid volume, abnormal rise in cerebrospinal fluid pressure, CSF, imbalance of cerebrospinal fluid production and absorption, spinal bifida, congenital hydrocephalus, acquired hydrocephalus, aqueductal stenosis, intracranial tumor obstruction, intracranial trauma, intracranial hemorrhage, intracranial infection, disorders of cerebrospinal fluid production, disorders of cerebrospinal fluid circulation, disorders of cerebrospinal fluid absorption, cerebrospinal fluid diversion, third ventriculostomy, normal pressure hydrocephalus
Follow-up: Hydrocephalus