Hairy Leukoplakia Follow-up
- Author: Denis P Lynch, DDS, PhD; Chief Editor: Dirk M Elston, MD more...
The complication associated with oral hairy leukoplakia (OHL) is an occasional candidal superinfection, which often results in an uncomfortable glossopyrosis (burning tongue).
Altered taste sensation is a rare complication.
The presence of oral lesions has a significant impact on health-related quality of life, because oral health is associated with physical and mental health.
The majority of patients with oral hairy leukoplakia tend to have significant immunosuppression at the time of diagnosis. Oral hairy leukoplakia occurs relatively soon after HIV seroconversion, typically before AIDS. Median CD4 count when oral hairy leukoplakia is first detected is between 235 and 468 per microliter.
Some studies of oral hairy leukoplakia in HIV-seropositive patients have shown that the median survival after the diagnosis of oral hairy leukoplakia is around 20 months. In patients with CD4 count greater than or equal to 300 per microliter, oral hairy leukoplakia is associated with median survival time of 25 months, compared to 52 months in patients with normal counts.
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