Horner Syndrome Treatment & Management

  • Author: Malvinder S Parmar, MB, MS, FRCP(C), FACP; Chief Editor: Jules E Harris, MD   more...
 
Updated: Jan 13, 2012
 

Medical Care

In general, appropriate treatment depends on the underlying cause. In many cases, no effective treatment is known. The goal of treatment is to eradicate the underlying disease process. Recognizing the presence of the syndrome and expedient referral to appropriate specialists are tantamount to early diagnosis.

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Consultations

Patients may require consultations with appropriate specialists (eg, pulmonologists, neurologists, internists) to manage the underlying cause.

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Contributor Information and Disclosures
Author

Malvinder S Parmar, MB, MS, FRCP(C), FACP  Assistant Professor (VPT), Faculty of Medicine, University of Ottawa Faculty of Medicine; Associate Professor, Department of Internal Medicine, Northern Ontario School of Medicine; Consulting Physician, Timmins and District Hospital, Ontario, Canada

Malvinder S Parmar, MB, MS, FRCP(C), FACP is a member of the following medical societies: American College of Physicians, American Society of Nephrology, Canadian Medical Association, Ontario Medical Association, and Royal College of Physicians and Surgeons of Canada

Disclosure: Nothing to disclose.

Specialty Editor Board

from Memorial Sloan-Kettering - Philip Schulman, MD  Chief, Medical Oncology, Department of Medicine, Memorial Sloan-Kettering Cancer Center; Clinical Professor, Department of Medicine, New York University School of Medicine

from Memorial Sloan-Kettering - Philip Schulman, MD is a member of the following medical societies: American Association for Cancer Research, American College of Physicians, American Society of Hematology, and Medical Society of the State of New York

Disclosure: Nothing to disclose.

Francisco Talavera, PharmD, PhD  Adjunct Assistant Professor, University of Nebraska Medical Center College of Pharmacy; Editor-in-Chief, Medscape Drug Reference

Disclosure: Medscape Salary Employment

Benjamin Movsas, MD  Vice-Chairman, Department of Radiation Oncology, Fox Chase Cancer Center

Benjamin Movsas, MD is a member of the following medical societies: American College of Radiology, American Radium Society, and American Society for Therapeutic Radiology and Oncology

Disclosure: Nothing to disclose.

Rajalaxmi McKenna, MD, FACP  Southwest Medical Consultants, SC, Department of Medicine, Good Samaritan Hospital, Advocate Health Systems

Rajalaxmi McKenna, MD, FACP is a member of the following medical societies: American Society of Clinical Oncology, American Society of Hematology, and International Society on Thrombosis and Haemostasis

Disclosure: Nothing to disclose.

Chief Editor

Jules E Harris, MD  Clinical Professor of Medicine, Section of Hematology/Oncology, University of Arizona College of Medicine, Arizona Cancer Center

Jules E Harris, MD is a member of the following medical societies: American Association for Cancer Research, American Association for the Advancement of Science, American Association of Immunologists, American Society of Hematology, and Central Society for Clinical Research

Disclosure: GlobeImmune Salary Consulting

References

  1. du Petit FP. Mémoire dans lequel il est démontré que les nerfs intercostaux fournissent des rameaux que portent des esprits dans les yeux. Paris, Mém: Hist Acad Roy Sci; 1727;1-19.

  2. Bernard C. Des phénomènes oculo-pupillaires produits par la section du nerf sympathique cervical: ils sont indépendants des phénomènes vasculaires calorifiques de la tête. Comptes rendus de l'Académie des sciences, Paris. 1852;55:381-88.

  3. Weir Mitchell S, Keen Jr W, Morehouse GR. Gunshot Wounds and Other Injuries of Nerves. Philadelphia: Lippincott; 1864. Reprinted, San Francisco: Norman Publishing; 1989.

  4. Horner JF. Über eine Form von Ptosis. Klinische Monatsblätter für Augenheilkunde, Stuttgart. 1869;7:193-8.

  5. Durham DG. Congenital hereditary Horner's syndrome. AMA Arch Ophthalmol. Nov 1958;60(5):939-40. [Medline].

  6. von Passow A. Okulare Paresen im Symptomenbilde des "Status dysraphicus", zugleich ein Beitrag zur Ätiologie der Sympathikusparese (Horner-Syndrom und Heterochromia iridis). Münchener medizinische Wochenshrift. 1934;74:1243-9.

  7. Krasnianski M, Georgiadis D, Grehl H, Lindner A. [Correlation of clinical and magnetic resonance imaging findings in patients with brainstem infarction]. Fortschr Neurol Psychiatr. May 2001;69(5):236-41. [Medline].

  8. Biousse V, Touboul PJ, D'Anglejan-Chatillon J, Lévy C, Schaison M, Bousser MG. Ophthalmologic manifestations of internal carotid artery dissection. Am J Ophthalmol. Oct 1998;126(4):565-77. [Medline].

  9. Piccoli M, Golinelli M, Colli G, Mullineris B, Melotti G. Homer syndrome after thoracoscopic apicectomy for spontaneous pneumothorax as a complication of chest tube placement. Chir Ital. Nov-Dec 2007;59(6):887-9. [Medline].

  10. González Martín-Moro J, Sastre-Pérez J, Pena Fernández I. Horner syndrome after temporomandibular joint arthroscopy: a new complication. J Oral Maxillofac Surg. Jun 2009;67(6):1320-2. [Medline].

  11. Allen AY, Meyer DR. Neck procedures resulting in Horner syndrome. Ophthal Plast Reconstr Surg. Jan-Feb 2009;25(1):16-8. [Medline].

  12. Monheit GD, Cohen JL. Long-term safety of repeated administrations of a new formulation of botulinum toxin type A in the treatment of glabellar lines: interim analysis from an open-label extension study. J Am Acad Dermatol. Sep 2009;61(3):421-5. [Medline].

  13. Raeder JG. Brain. Oxford: 1924:47;149-158.

  14. Rombolá CA, Atance PL, Honguero Martínez AF. Claude Bernard-Horner Syndrome as a Rare Complication of Postoperative Pleural Drainage. Arch Bronconeumol. 2008;44:116-7. [Medline].

  15. Arnold M, Baumgartner RW, Stapf C, Nedeltchev K, Buffon F, Benninger D, et al. Ultrasound diagnosis of spontaneous carotid dissection with isolated Horner syndrome. Stroke. Jan 2008;39(1):82-6. [Medline]. [Full Text].

  16. Morales J, Brown SM, Abdul-Rahim AS, Crosson CE. Ocular effects of apraclonidine in Horner syndrome. Arch Ophthalmol. Jul 2000;118(7):951-4. [Medline].

  17. Koc F, Kavuncu S, Kansu T, Acaroglu G, Firat E. The sensitivity and specificity of 0.5% apraclonidine in the diagnosis of oculosympathetic paresis. Br J Ophthalmol. Nov 2005;89(11):1442-4. [Medline].

  18. Mughal M, Longmuir R. Current pharmacologic testing for Horner syndrome. Curr Neurol Neurosci Rep. Sep 2009;9(5):384-9. [Medline].

  19. Cooper-Knock J, Pepper I, Hodgson T, Sharrack B. Early diagnosis of Horner syndrome using topical apraclonidine. J Neuroophthalmol. Sep 2011;31(3):214-6. [Medline].

  20. Kawasaki A, Borruat FX. False negative apraclonidine test in two patients with Horner syndrome. Klin Monatsbl Augenheilkd. May 2008;225(5):520-2. [Medline].

  21. Adams RD, Victor M. Eye signs in neurologic diagnosis. In: Principles of Neurology. 5th ed. New York: McGraw-Hill, Inc; 1993:375-9.

  22. Biousse V, Touboul PJ, D'Anglejan-Chatillon J, Levy C, Schaison M, et al. Ophthalmologic manifestations of internal carotid artery dissection. Am J Ophthalmol. Oct 1998;126(4):565-77. [Medline].

  23. Birch C. Horner. In: Names We Remember 56 Eponymous Medical Biographies. Kent, England: Ravenswood, Beckenham; 70-72.

  24. Bucci T, Califano L. Bernard-Horner's syndrome: unusual complication after neck dissection. J Oral Maxillofac Surg. Apr 2008;66(4):833. [Medline].

  25. Dziewas R, Konrad C, Drager B, Evers S, Besselmann M, Ludemann P, et al. Cervical artery dissection--clinical features, risk factors, therapy and outcome in 126 patients. J Neurol. Oct 2003;250(10):1179-84. [Medline].

  26. Lee JH, Lee HK, Lee DH, Choi CG, Kim SJ, Suh DC. Neuroimaging strategies for three types of Horner syndrome with emphasis on anatomic location. AJR Am J Roentgenol. Jan 2007;188(1):W74-W81. [Medline].

  27. Magalini SI, Magalini SC. Dictionary of Medical Syndromes. Philadelphia, Pa: Lippincott Williams & Wilkins; 1997.

  28. McCorry D, Bamford J. Painful Horner's syndrome caused by carotid dissection. Postgrad Med J. Mar 2004;80(941):164. [Medline].

  29. Merrison AF, Lhatoo SD. Horner's syndrome postpartum. BJOG. Jan 2004;111(1):86-8. [Medline].

  30. Morris JG, Lee J, Lim CL. Facial sweating in Horner's syndrome. Brain. Sep 1984;107 ( Pt 3):751-8. [Medline].

  31. Nautiyal A, Singh S, DiSalle M, O'Sullivan J. Painful Horner syndrome as a harbinger of silent carotid dissection. PLoS Med. Jan 2005;2(1):e19. [Medline].

  32. Reede DL, Garcon E, Smoker WR, Kardon R. Horner's syndrome: clinical and radiographic evaluation. Neuroimaging Clin N Am. May 2008;18(2):369-85, xi. [Medline].

  33. Walton KA, Buono LM. Horner syndrome. Curr Opin Ophthalmol. Dec 2003;14(6):357-63. [Medline].

  34. Weiner WJ, Goetz C. Disorders of ocular movement and pupillary function. In: Neurology for the Non-neurologist. 1999. Lippincott, Williams & Wilkins; 4th ed:242-5.

 
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