eMedicine Specialties > Psychiatry > Addiction

Opioid Abuse: Multimedia

Author: William J Meehan, MD, Chief Resident in Clinical Research, Department of Psychiatry, University of Massachusetts Memorial Medical Center, University of Massachusetts Medical School
Coauthor(s): Steven A Adelman, MD, Director, Behavioral Health and Addiction Medicine, Harvard Vanguard Medical Associates
Contributor Information and Disclosures

Updated: Jul 31, 2009

Multimedia

Schematic diagram of the brain-reward circuitry o...
(Enlarge Image)
Media file 1: Schematic diagram of the brain-reward circuitry of the mammalian (laboratory rat) brain with sites at which various abusable substances appear to act to enhance brain-reward and, thus, to induce drug-taking behavior and possibly drug craving. Courtesy William & Wilkins Substance Abuse by Eliot L Gardner.KEY - Nucleus accumbens (Acc), ventral tegmental area (VTA), amygdala (AMYG), locus ceruleus (LC), dopaminergic mesolimbic system (DA), ventral pallidum (VP), noradrenergic fibers (NF), enkephalinergic outflow (ENK), frontal cortex (FCX), GABAergic inhibitory fiber system (GABA), dynorphinergic outflow (DYN),component of reward circuitry preferentially activated by electrical intracranial self-stimulation (ICSS).
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Schematic diagram of the brain-reward circuitry o...

Schematic diagram of the brain-reward circuitry of the mammalian (laboratory rat) brain with sites at which various abusable substances appear to act to enhance brain-reward and, thus, to induce drug-taking behavior and possibly drug craving. Courtesy William & Wilkins Substance Abuse by Eliot L Gardner.KEY - Nucleus accumbens (Acc), ventral tegmental area (VTA), amygdala (AMYG), locus ceruleus (LC), dopaminergic mesolimbic system (DA), ventral pallidum (VP), noradrenergic fibers (NF), enkephalinergic outflow (ENK), frontal cortex (FCX), GABAergic inhibitory fiber system (GABA), dynorphinergic outflow (DYN),component of reward circuitry preferentially activated by electrical intracranial self-stimulation (ICSS).

More on Opioid Abuse

Overview: Opioid Abuse
Differential Diagnoses & Workup: Opioid Abuse
Treatment & Medication: Opioid Abuse
Follow-up: Opioid Abuse
Multimedia: Opioid Abuse
References
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References

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Further Reading

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Keywords

opioid abuse, narcotic abuse, drug abuse, pain relievers, endorphins, heroin, morphine, opium, PCP, opioid receptors, intravenous drug use, IV drug use, intravenous drug user, IDU, drug dependence, pain reliever abuse

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Contributor Information and Disclosures

Author

William J Meehan, MD, Chief Resident in Clinical Research, Department of Psychiatry, University of Massachusetts Memorial Medical Center, University of Massachusetts Medical School
Disclosure: Nothing to disclose.

Coauthor(s)

Steven A Adelman, MD, Director, Behavioral Health and Addiction Medicine, Harvard Vanguard Medical Associates
Steven A Adelman, MD is a member of the following medical societies: American Academy of Addiction Psychiatry, American Psychiatric Association, American Society of Addiction Medicine, and Massachusetts Medical Society
Disclosure: Nothing to disclose.

Medical Editor

Barry I Liskow, MD, Professor of Psychiatry, Vice Chairman, Psychiatry Department, Director, Psychiatric Residency Program, University of Kansas School of Medicine; Director, Psychiatric Outpatient Clinic, The University of Kansas Medical Center
Barry I Liskow, MD is a member of the following medical societies: American Academy of Clinical Psychiatrists, American Academy of Psychiatrists in Alcoholism and Addictions, American Medical Association, American Psychiatric Association, and Research Society on Alcoholism
Disclosure: Nothing to disclose.

Pharmacy Editor

Francisco Talavera, PharmD, PhD, Senior Pharmacy Editor, eMedicine
Disclosure: eMedicine Salary Employment

Managing Editor

Eduardo Dunayevich, MD, Adjunct Assistant Professor, Department of Psychiatry, University of Cincinnati; Clinical Research Physician, Neuroscience, Lilly Research Laboratories
Eduardo Dunayevich, MD is a member of the following medical societies: American Psychiatric Association
Disclosure: Nothing to disclose.

CME Editor

Harold H Harsch, MD, Program Director of Geropsychiatry, Department of Geriatrics/Gerontology, Associate Professor, Department of Psychiatry and Department of Medicine, Froedtert Hospital, Medical College of Wisconsin
Harold H Harsch, MD is a member of the following medical societies: American Psychiatric Association
Disclosure: lilly Honoraria Speaking and teaching; Forest Labs Honoraria Speaking and teaching; AstraZeneca Honoraria Speaking and teaching; Pfizer Grant/research funds Speaking and teaching; Northstar Grant/research funds Research; Novartis Grant/research funds research; Pfizer  Speaking and teaching; Sanofi-avetis Grant/research funds research; Otsuke Grant/research funds reseach; GlaxoSmithKline Grant/research funds research

Chief Editor

Stephen Soreff, MD, President of Education Initiatives, Nottingham, NH; Faculty, Metropolitan College of Boston University, Boston, MA
Stephen Soreff, MD is a member of the following medical societies: American College of Mental Health Administration and American Psychosomatic Society
Disclosure: Nothing to disclose.

 
 
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