Updated: Oct 22, 2009
Factitious disorder refers to the psychiatric condition in which a patient deliberately produces or falsifies symptoms of illness for the sole purpose of assuming the sick role. Patients with factitious disorder waste precious time and resources through unnecessary hospital admissions, expensive investigatory tests, and sometimes, lengthy hospital stays. Moreover, patients with factitious disorder are among the most challenging and troublesome for busy clinicians. Patients with factitious disorder can generate feelings of anger, frustration, or bewilderment, because they violate the expectations of physicians and staff that patients should "behave like patients." Patients with factitious disorder disobey the following unwritten rules of being a patient: (1) patients attempt to provide an honest history; (2) symptoms result from accident, injury, or chance; and (3) patients are seeking treatment with the goal of recovering and so will cooperate with treatment toward that end.
Patients with factitious disorder likely have been present throughout human history. Their appearance in the literature extends back to the time of the Roman physician Galen who wrote about them in the second century. In the 1800s, the British physician Gavin described how some soldiers and seamen pretended illness to excite compassion or interest.
The modern history of factitious disorder began in 1951 when a clinician (Asher) described case reports of patients who habitually migrate from hospital to hospital, seeking admission through feigned symptoms while embellishing their personal history.1 He assigned the name Munchausen syndrome to this condition after Baron von Munchausen, a well-respected, retired German cavalry officer who had tales of his life stolen and parodied in a booklet in 1785. Persons with Munchausen syndrome were said to typically (1) exhibit numerous surgical scars, especially in the abdomen, (2) display a truculent or evasive manner, (3) provide a dramatic medical history of questionable veracity, and (4) attempt to conceal such documents as hospital discharge forms or insurance claims. Asher distinguished abdominal, hemorrhagic, and neurologic subtypes.
Since the publication of Asher's article, numerous reports of patients producing or falsifying almost every conceivable kind of illness have appeared in the literature. The type of patient described by Asher is now thought to represent a minority of cases of factitious disorder. The term Munchausen syndrome most appropriately refers to the subset of patients who have a chronic variant of factitious disorder with predominantly physical signs and symptoms. In practice, however, many still use the term Munchausen syndrome interchangeably with factitious disorder. In 1976, the term Munchausen syndrome by proxy entered the medical lexicon and came to describe cases in which an individual artificially produces illness in another person; typically a mother who produces illness in a young child.
The Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision (DSM-IV-TR)2 requires that the following 3 criteria be met for the diagnosis of factitious disorder: (1) intentional production or feigning of physical or psychological signs or symptoms, (2) motivation for the behavior is to assume the sick role, and (3) absence of external incentives for the behavior (eg, economic gain, avoiding legal responsibility, improving physical well-being, as in malingering).
The DSM-IV-TR recognizes the following 3 types of factitious disorder: (1) factitious disorder with predominantly psychological signs and symptoms, (2) factitious disorder with predominantly physical signs and symptoms, and (3) factitious disorder with combined psychological and physical signs and symptoms.
A fourth type, factitious disorder not otherwise specified, includes those disorders with factitious symptoms that do not meet the criteria for factitious disorder. The DSM-IV-TR places factitious disorder by proxy (ie, Munchausen syndrome by proxy) into this category, defining it as "the intentional production or feigning of physical or psychological signs or symptoms in another person who is under the individual's care for the purpose of indirectly assuming the sick role." Factitious disorder by proxy has yet to be recognized as an official separate category in the DSM-IV-TR. Appendix B of the DSM-IV-TR lists the following research criteria for factitious disorder by proxy.
Case study
A 25-year-old nursing student was admitted to the medical service of a teaching hospital with complaints of hematamesis. She had been seen at another prominent teaching hospital and diagnosed with peptic ulcer disease but treatment had failed to resolve her symptoms. She requested surgical intervention to resolve the problem. After endoscopy failed to reveal any area of bleeding in the stomach, she became upset at the hospital staff for their inability to help her. She became angry when visited by the psychiatry consultation team and denied having any psychiatric problems, insisting that the medical system had failed her.
Due to lack of findings, factitious disorder was considered and staff was advised to observe her closely over the next few days. She was seen sticking her finger up her nose and causing it to bleed into the back of her throat. She then swallowed the blood. When she was confronted by the medical team she became angry and signed out of the hospital, refusing psychiatric follow-up. The internist on the medical team subsequently learned that she had been admitted to a nearby hospital with an abscess in her thigh. She had apparently injected a foreign substance into her thigh. She was diagnosed with factitious disorder with somatic symptoms.
As with many psychiatric illnesses, the pathophysiology of factitious disorder is unclear. Case reports of abnormalities on MRIs of the brains of patients with chronic factitious disorder suggest that brain biology may play a role in some cases. For example, in one report, a patient with Munchausen syndrome that underwent SPECT scan was found to have marked hyperperfusion of the right hemithalamus.3
In addition, some patients with factitious disorder have displayed abnormalities on psychological testing. Results of EEG studies have thus far been nonspecific.
The prevalence of factitious disorder is unclear. Many authorities believe the condition is underdiagnosed because it involves willful deception, which may be missed by medical staff. Conversely, the prevalence of chronic factitious disorder may be overdiagnosed in some cases because the same patients with factitious disorder may migrate from hospital to hospital. The frequency of presentation of various factitious illnesses (eg, which factitious illnesses are most common) is unclear. However, most researchers agree that the prevalence of factitious psychological symptoms is much lower than the prevalence of factitious physical symptoms. Studies investigating the prevalence of factitious disorder have found the following:
Whether the epidemiology of factitious disorder differs in countries other than the US is unclear.
Factitious disorder can result in morbidity and mortality from the patient's re-creation of actual medical conditions (eg, exogenous administration of insulin) or from the procedures undertaken by the physician to diagnose or treat the condition (eg, unnecessary cardiac catheterizations, surgeries). The factitious production of illness also can lead to emotional distress and suffering for the patient and those close to the patient. No studies have quantified the total estimated morbidity and mortality from factitious disorder.
Persons with factitious disorder are usually female and employed in medical fields such as nursing or medical technology. Working in the medical field provides knowledge of how disease might be produced artificially and provides access to equipment (eg, syringes, chemicals) with which to do so.
Persons with factitious disorder tend to be women aged 20-40 years. Persons with chronic factitious disorder (ie, Munchausen syndrome) tend to be middle-aged men.5 Factitious disorder has been noted in the pediatric population.6
Patients may feign illness by means of a factitious history alone (eg, falsely claiming to have had a syncopal episode), by a factitious history plus the manipulation of assessment instruments (eg, claiming illness and manipulating a thermometer to show fever), by a factitious history and the use of external agents that mimic disease (eg, adding exogenous blood to urine and claiming hematuria), or by a factitious history and inducing an actual medical condition (eg, injecting bacteria to produce infection, ingesting CNS-active medications to induce psychiatric symptoms). Individuals with an actual medical condition may provide a fictitious history consistent with their condition (eg, pseudoseizures in a patient with epilepsy).
Detection of factitious disorder is typically slowed by the natural tendency among physicians to believe what patients say. Indeed, this tendency may be even greater because many patients with factitious disorder work in the health care field and are colleagues. The detection of factitious disorder among those who have an actual medical condition can be even more difficult.
Suspicion of factitious disorder is raised when the patient has multiple surgical scars or a gridiron abdomen, indicating the chronic form of factitious disorder, or with evidence of self-induced physical signs.
Mental Status Examination
Patients with factitious disorder may vary in their presentation, and no findings have been shown to be pathognomonic. The following findings are possible:
An example of a patient with factitious disorder follows.
A woman presented to the emergency department as disheveled with poor eye contact. She was dressed unremarkably in street clothes. She was unable to answer basic questions about her past and grimaced as she appeared to concentrate, to no avail. She spoke with an English accent and claimed no memory of who she was or how she got to the hospital. She cooperated with the examiner but could provide little useful information. Her mood was serious and affect was restricted. Thought process was linear. Thought content was impoverished. She did not endorse any hallucinations, delusions, or thoughts about suicide or homicide.
After some efforts by a social worker at the hospital, she was discovered to be a house wife from another city who was in an unhappy marriage and decided to leave to start a new life and had a history of psychiatric hospitalizations. She lost her British accent and acknowledged that she indeed had simulated her symptoms and her history. She was diagnosed with factitious disorder with predominantly psychological signs and symptoms.
Delusional Disorder
Depression
Schizophrenia
Factitious disorder appears in the differential diagnosis for many illnesses. Accordingly, factitious disorder must be distinguished from a true or real general medical condition or mental disorder, including those that are (1) due to accident or chance, (2) due to noncompliance with treatment, (3) iatrogenic, or (4) the result of attempted suicide, homicide, or self-mutilation.
Factitious disorder must also be distinguished from the somatoform illnesses and malingering. Factitious disorder has been believed to fall on a continuum between these illnesses.
Somatoform disorders include the following conditions:
Psychiatrists often observe that in the case of somatoform disorders, the production of the symptoms of illness is not intentional, and the motivation for illness is unconscious; in factitious disorder, symptoms are produced intentionally but for unconscious reasons; and in malingering, symptom production is intentional and conscious to achieve an external incentive beyond assuming the sick role (eg, evading the police, obtaining compensation, getting a bed for the night). In practice, however, determining whether an external incentive exists can sometimes be difficult.
The differential diagnosis for factitious disorder by proxy includes the following possibilities:
Patients with other psychiatric diagnoses can also present with somatic preoccupation that is not supported by findings from physical examination, laboratory testing, or imaging. Patients with major depression with psychotic features and delusional disorder (somatoform type) can present with somatic delusions. Associated features of these conditions should facilitate the differential diagnosis.
Provide medical care as needed to treat comorbid conditions and complications arising from induced illness.
Provide surgical care as needed to treat comorbid conditions and complications arising from induced illness.
There is a lack of evidence to support the efficacy of any particular pharmacological intervention in treating factitious disorder. However, pharmacologic therapy for concurrent psychiatric diagnoses is indicated.
Further inpatient care may be required if patients relapse. This includes the treatment of any medical or surgical conditions as well as psychiatric hospitalization when necessary.
Close psychiatric follow-up care and monitoring in the outpatient setting is indicated to prevent relapse. Close medical follow-up care may also be necessary, depending on the condition.
Transfer from the medical floor to an inpatient psychiatric department is indicated if patients agree to treatment. In rare cases, involuntary hospitalization may be possible if the patient's health is jeopardized severely by continued production of factitious illness (eg, the patient has already lost a kidney because of factitious disorder and is in danger of losing another).
Deterrence and prevention involve clear documentation of patients with a known history of factitious disorder, although it does not involve blacklisting.
Complications may arise from the induction of factitious illness or arise iatrogenically from the workup or treatment for the condition, in addition to producing high health care costs.
A patient with factitious disorder is entitled to the same rights to privacy and confidentiality of information as any other patient.
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Munchausen syndrome, Munchausen syndrome by proxy, factitious disorder, Ganser syndrome, somatoform illnesses, malingering, somatization disorder, conversion disorder, hypochondriasis
Todd S Elwyn, MD, Staff Psychiatrist, Tripler Army Medical Center, Schofield Barracks Soldier Assistance Center
Todd S Elwyn, MD is a member of the following medical societies: American Academy of Child and Adolescent Psychiatry, American Academy of Psychiatry and the Law, American College of Legal Medicine, and American Psychiatric Association
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Iqbal Ahmed, MBBS, Professor, Department of Psychiatry, John A Burns School of Medicine, University of Hawaii
Iqbal Ahmed, MBBS is a member of the following medical societies: Academy of Psychosomatic Medicine, American Association for Geriatric Psychiatry, American Neuropsychiatric Association, and American Psychiatric Association
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Sarah C Aronson, MD, Associate Professor, Departments of Psychiatry and Medicine, Case Western Reserve School of Medicine/University Hospitals of Cleveland
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Harold H Harsch, MD, Program Director of Geropsychiatry, Department of Geriatrics/Gerontology, Associate Professor, Department of Psychiatry and Department of Medicine, Froedtert Hospital, Medical College of Wisconsin
Harold H Harsch, MD is a member of the following medical societies: American Psychiatric Association
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Stephen Soreff, MD is a member of the following medical societies: American College of Mental Health Administration and American Psychosomatic Society
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