eMedicine Specialties > Pulmonology > Occupational Lung Diseases
Berylliosis: Multimedia
Updated: Nov 19, 2008
Multimedia
![]() | Media file 1: A high-resolution CT scan of the chest showing the typical ground glass appearance in a patient with chronic beryllium disease, or berylliosis. |
![]() | Media file 2: A histopathology slide (hematosin and eosin stain) showing the typical well-formed granuloma of chronic beryllium disease, or berylliosis. |
More on Berylliosis |
| Overview: Berylliosis |
| Differential Diagnoses & Workup: Berylliosis |
| Treatment & Medication: Berylliosis |
| Follow-up: Berylliosis |
Multimedia: Berylliosis |
| References |
| « Previous Page |
References
Saltini C, Winestock K, Kirby M, Pinkston P, Crystal RG. Maintenance of alveolitis in patients with chronic beryllium disease by beryllium-specific helper T cells. N Engl J Med. Apr 27 1989;320(17):1103-9. [Medline].
Berlin JM, Taylor JS, Sigel JE, Bergfeld WF, Dweik RA. Beryllium dermatitis. J Am Acad Dermatol. Nov 2003;49(5):939-41. [Medline].
Richeldi L, Sorrentino R, Saltini C. HLA-DPB1 glutamate 69: a genetic marker of beryllium disease. Science. Oct 8 1993;262(5131):242-4. [Medline].
Barna BP, Culver DA, Yen-Lieberman B, Dweik RA, Thomassen MJ. Clinical application of beryllium lymphocyte proliferation testing. Clin Diagn Lab Immunol. Nov 2003;10(6):990-4. [Medline].
Newman LS. Significance of the blood beryllium lymphocyte proliferation test. Environ Health Perspect. Oct 1996;104 Suppl 5:953-6. [Medline].
Rossman MD, Kern JA, Elias JA, Cullen MR, Epstein PE, Preuss OP, et al. Proliferative response of bronchoalveolar lymphocytes to beryllium. A test for chronic beryllium disease. Ann Intern Med. May 1988;108(5):687-93. [Medline].
Newman LS, Buschman DL, Newell JD Jr, Lynch DA. Beryllium disease: assessment with CT. Radiology. Mar 1994;190(3):835-40. [Medline].
Kreiss K, Mroz MM, Newman LS, Martyny J, Zhen B. Machining risk of beryllium disease and sensitization with median exposures below 2 micrograms/m3. Am J Ind Med. Jul 1996;30(1):16-25. [Medline].
Amicosante M, Berretta F, Franchi A, Rogliani P, Dotti C, Losi M, et al. HLA-DP-unrestricted TNF-alpha release in beryllium-stimulated peripheral blood mononuclear cells. Eur Respir J. Nov 2002;20(5):1174-8. [Medline].
Culver DA, Dweik RA. Chronic beryllium disease. Clin Pulm Med. 2003;10:72-9.
Kreiss K, Miller F, Newman LS, Ojo-Amaize EA, Rossman MD, Saltini C. Chronic beryllium disease--from the workplace to cellular immunology, molecular immunogenetics, and back. Clin Immunol Immunopathol. May 1994;71(2):123-9. [Medline].
Kreiss K, Mroz MM, Zhen B, Wiedemann H, Barna B. Risks of beryllium disease related to work processes at a metal, alloy, and oxide production plant. Occup Environ Med. Aug 1997;54(8):605-12. [Medline].
Kreiss K, Newman LS, Mroz MM, Campbell PA. Screening blood test identifies subclinical beryllium disease. J Occup Med. Jul 1989;31(7):603-8. [Medline].
Kriebel D, Brain JD, Sprince NL, Kazemi H. The pulmonary toxicity of beryllium. Am Rev Respir Dis. Feb 1988;137(2):464-73. [Medline].
Meyer KC. Beryllium and lung disease. Chest. Sep 1994;106(3):942-6. [Medline].
MOSBY'S GENRx-The Complete Reference For Generic And Brand Drugs. 9th ed. St. Louis, Mo: Mosby-Year Book; 1999.
Müller-Quernheim J, Gaede KI, Fireman E, Zissel G. Diagnoses of chronic beryllium disease within cohorts of sarcoidosis patients. Eur Respir J. Jun 2006;27(6):1190-5. [Medline].
Newman LS. Immunology, genetics, and epidemiology of beryllium disease. Chest. Mar 1996;109(3 Suppl):40S-43S. [Medline].
Newman LS, Kreiss K, King TE Jr, Seay S, Campbell PA. Pathologic and immunologic alterations in early stages of beryllium disease. Re-examination of disease definition and natural history. Am Rev Respir Dis. Jun 1989;139(6):1479-86. [Medline].
Newman LS, Lloyd J, Daniloff E. The natural history of beryllium sensitization and chronic beryllium disease. Environ Health Perspect. Oct 1996;104 Suppl 5:937-43. [Medline].
Newman LS, Mroz MM, Balkissoon R, Maier LA. Beryllium sensitization progresses to chronic beryllium disease: a longitudinal study of disease risk. Am J Respir Crit Care Med. Jan 1 2005;171(1):54-60. [Medline].
Pappas GP, Newman LS. Early pulmonary physiologic abnormalities in beryllium disease. Am Rev Respir Dis. Sep 1993;148(3):661-6. [Medline].
Saber W, Dweik RA. A 65-year-old factory worker with dyspnea on exertion and a normal chest x-ray. Cleve Clin J Med. Nov 2000;67(11):791-2, 794, 797-8, 800. [Medline].
Stokes RF, Rossman MD. Blood cell proliferation response to beryllium: analysis by receiver-operating characteristics. J Occup Med. Jan 1991;33(1):23-8. [Medline].
Further Reading
Keywords
berylliosis, beryllium, Be, chronic beryllium disease, CBD, acute beryllium disease, acute chemical pneumonitis




Multimedia: Berylliosis