Respiratory Acidosis Differential Diagnoses

  • Author: Ryland P Byrd Jr, MD; Chief Editor: Zab Mosenifar, MD   more...
 
Updated: Oct 3, 2011
 
 

Diagnostic Considerations

All potential causes of respiratory acidosis should be considered (see Etiology and Pathophysiology). These include lung disease, neuromuscular diseases, and central neurologic depression. Thus, conditions that should be considered include amyotrophic lateral sclerosis, muscular dystrophy, severe kyphoscoliosis, Guillain-Barré syndrome, and myasthenia gravis.

Differential Diagnoses

Proceed to Workup
 
 
Contributor Information and Disclosures
Author

Ryland P Byrd Jr, MD  Professor, Department of Internal Medicine, Division of Pulmonary Medicine and Critical Care Medicine, Program Director of Pulmonary Diseases and Critical Care Medicine Fellowship, East Tennessee State University, James H Quillen College of Medicine; Medical Director of Respiratory Therapy, James H Quillen Veterans Affairs Medical Center

Ryland P Byrd Jr, MD is a member of the following medical societies: American College of Chest Physicians and American Thoracic Society

Disclosure: Nothing to disclose.

Coauthor(s)

Thomas M Roy, MD  Chief, Division of Pulmonary Diseases and Critical Care Medicine, Quillen Mountain Home Veterans Affairs Medical Center; Professor, Department of Internal Medicine, Division of Pulmonary Medicine, East Tennessee State University, James H Quillen College of Medicine

Thomas M Roy, MD is a member of the following medical societies: American College of Chest Physicians, American College of Physicians, American Medical Association, American Thoracic Society, Southern Medical Association, and Wilderness Medical Society

Disclosure: Nothing to disclose.

Specialty Editor Board

Oleh Wasyl Hnatiuk, MD  Program Director, National Capital Consortium, Pulmonary and Critical Care, Walter Reed Army Medical Center; Associate Professor, Department of Medicine, Uniformed Services University of Health Sciences

Oleh Wasyl Hnatiuk, MD is a member of the following medical societies: American College of Chest Physicians, American College of Physicians, and American Thoracic Society

Disclosure: Nothing to disclose.

Francisco Talavera, PharmD, PhD  Adjunct Assistant Professor, University of Nebraska Medical Center College of Pharmacy; Editor-in-Chief, Medscape Drug Reference

Disclosure: Medscape Salary Employment

Chief Editor

Zab Mosenifar, MD  Director, Division of Pulmonary and Critical Care Medicine, Director, Women's Guild Pulmonary Disease Institute, Professor and Executive Vice Chair, Department of Medicine, Cedars Sinai Medical Center, University of California, Los Angeles, David Geffen School of Medicine

Zab Mosenifar, MD is a member of the following medical societies: American College of Chest Physicians, American College of Physicians, American Federation for Medical Research, and American Thoracic Society

Disclosure: Nothing to disclose.

Additional Contributors

The authors and editors of Medscape Reference gratefully acknowledge the contributions of previous authors Jackie A Hayes, MD, FCCP, and Wael El Minaoui, MBBS,to the development and writing of the source article.

References
  1. Murray J, Nadel J. Hypoventilation syndromes. In: Textbook of Respiratory Medicine. Vol 2. 4th ed. Philadelphia, Pa: WB Saunders; 2005:2075-80.

  2. Adnet F, Plaisance P, Borron SW, Levy A, Payen D. Prolonged severe hypercapnia complicating near fatal asthma in a 35-year-old woman. Intensive Care Med. Dec 1998;24(12):1335-8. [Medline].

  3. Cham GW, Tan WP, Earnest A, Soh CH. Clinical predictors of acute respiratory acidosis during exacerbation of asthma and chronic obstructive pulmonary disease. Eur J Emerg Med. Sep 2002;9(3):225-32. [Medline].

  4. Theerthakarai R, El-Halees W, Javadpoor S, Khan MA. Severe pectus excavatum associated with cor pulmonale and chronic respiratory acidosis in a young woman. Chest. Jun 2001;119(6):1957-61. [Medline].

  5. Ehrsam RE, Heigenhauser GJ, Jones NL. Effect of respiratory acidosis on metabolism in exercise. J Appl Physiol. Jul 1982;53(1):63-9. [Medline].

  6. Kazmaier S, Weyland A, Buhre W, et al. Effects of respiratory alkalosis and acidosis on myocardial blood flow and metabolism in patients with coronary artery disease. Anesthesiology. Oct 1998;89(4):831-7. [Medline].

  7. Wu JY, Kuo PH, Fan PC, Wu HD, Shih FY, Yang PC. The Role of Non-invasive Ventilation and Factors Predicting Extubation Outcome in Myasthenic Crisis. Neurocrit Care. 2009;10(1):35-42. [Medline].

  8. Zhang WB, Wang XY, Tian XY, Zhang H, Wang ZP, Gao YY. [Clinical value of noninvasive positive-pressure ventilation in chronic obstruction pulmonary disease combined with type II respiratory failure: a 4-year retrospective study]. Zhongguo Wei Zhong Bing Ji Jiu Yi Xue. Oct 2008;20(10):601-3. [Medline].

  9. Terragni PP, Birocco A, Faggiano C, Ranieri VM. Extracorporeal CO(2) Removal. Contrib Nephrol [serial online]. 2010 April 20;165:185-196. [Medline]. Available at http://-.

  10. Ali A, Flageole H. Diaphragmatic pacing for the treatment of congenital central alveolar hypoventilation syndrome. J Pediatr Surg. May 2008;43(5):792-6. [Medline].

  11. Pollock JM, Deibler AR, Whitlow CT, et al. Hypercapnia-Induced Cerebral Hyperperfusion: An Underrecognized Clinical Entity. AJNR Am J Neuroradiol. Oct 14 2008;[Medline].

  12. Duiverman ML, Wempe JB, Bladder G, et al. Nocturnal non-invasive ventilation in addition to rehabilitation in hypercapnic patients with COPD. Thorax. Dec 2008;63(12):1052-7. [Medline].

  13. Kellum JA. Determinants of plasma acid-base balance. Crit Care Clin. Apr 2005;21(2):329-46. [Medline].

  14. Wiseman AC, Linas S. Disorders of potassium and acid-base balance. Am J Kidney Dis. May 2005;45(5):941-9. [Medline].

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