Postpolio Syndrome Treatment & Management

  • Author: Flor M Muñiz, MD; Chief Editor: Denise I Campagnolo, MD, MS   more...
 
Updated: Aug 8, 2011
 

Rehabilitation Program

Physical Therapy

The basic management principles for individuals with postpolio syndrome include energy conservation and pacing one's activities. Although basic, these activity modifications may be difficult for some patients to accept. Psychological interventions, such as cognitive behavior therapy, may also be initiated to help reduce fatigue.[7]

Reports on exercises are conflicting, but the key factor seems to be exercise intensity. Strengthening exercises should be nonfatiguing. A specific suggestion is to exercise every other day, and the perceived rate of exertion should be less than "very hard." Loads should be held for only 4-5 seconds, and there should be a 10-second rest between bouts and a 5-minute rest between sets. The patient should perform about 3 sets of 5-10 repetitions.[8]

In addition to specifying exercises for those body areas experiencing the deleterious effects of disuse, the exercise prescription also should consider how to protect (1) muscles and joints that are experiencing the adverse effects of overuse and (2) body areas with very significant chronic weakness (generally, areas where the muscles have less than antigravity strength on manual muscle testing).

Results of these exercises vary. Strengthening programs performed as described show a 60% increase on isokinetic strength, improved cardiorespiratory status, no decline in strength in 6-12 months, and 5% increase in isometric strength.

Electrical stimulation has been used to strengthen weakened muscles or to reeducate muscles weakened through disuse, as well as to decrease pain.

For myofascial pain, consider heat, electrical stimulation, trigger point injections, stretching exercises, biofeedback, muscle relaxation exercises, or static magnetic fields for trigger points.

For gait disturbances, assistive devices can be used, but sometimes patients refuse because of the philosophy of "not giving in." Treatment also can involve limitation of ambulation to shorter distances and the use of orthotics for joint protection.

Occupational Therapy

Patients with postpolio syndrome usually benefit from different adaptive techniques and equipment to perform any activities of daily living, as well as education and energy conservation techniques.

Speech Therapy

Speech evaluation in persons with postpolio syndrome usually is recommended with any suggestion of swallowing problems. The therapist teaches the patient about different techniques to improve his/her swallowing function.

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Consultations

  • Pulmonologists
    • When the patient with postpolio syndrome reports respiratory problems, a full pulmonary evaluation may be required.
    • Sometimes, the patient may even need mechanical respiratory support.
    • A sleep evaluation may be necessary for suspected sleep apnea.
  • Orthopedists - The patient may present with various joint deformities that may require orthoses and sometimes even surgery.
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Contributor Information and Disclosures
Author

Flor M Muñiz, MD  Assistant Professor, Department of Physical Medicine and Rehabilitation, McMaster University, Hamilton, Ontario

Flor M Muñiz, MD is a member of the following medical societies: American Medical Association, Canadian Association of Physical Medicine and Rehabilitation, and Canadian Medical Association

Disclosure: Nothing to disclose.

Coauthor(s)

Gerald J Herbison, MD  Professor, Department of Rehabilitation Medicine, Jefferson Medical College, Thomas Jefferson University

Disclosure: Nothing to disclose.

Specialty Editor Board

Martin K Childers, DO, PhD  Professor, Department of Neurology, Wake Forest University School of Medicine; Professor, Rehabilitation Program, Institute for Regenerative Medicine, Wake Forest Baptist Medical Center

Martin K Childers, DO, PhD is a member of the following medical societies: American Academy of Physical Medicine and Rehabilitation, American Congress of Rehabilitation Medicine, American Osteopathic Association, Christian Medical & Dental Society, and Federation of American Societies for Experimental Biology

Disclosure: Allergan pharma Consulting fee Consulting

Francisco Talavera, PharmD, PhD  Adjunct Assistant Professor, University of Nebraska Medical Center College of Pharmacy; Editor-in-Chief, Medscape Drug Reference

Disclosure: Medscape Salary Employment

Kat Kolaski, MD  Assistant Professor, Departments of Orthopedic Surgery and Pediatrics, Wake Forest University School of Medicine

Kat Kolaski, MD is a member of the following medical societies: American Academy for Cerebral Palsy and Developmental Medicine and American Academy of Physical Medicine and Rehabilitation

Disclosure: Nothing to disclose.

Kelly L Allen, MD  Medical Director, Medevals

Disclosure: Nothing to disclose.

Chief Editor

Denise I Campagnolo, MD, MS  Director of Multiple Sclerosis Clinical Research and Staff Physiatrist, Barrow Neurology Clinics, St Joseph's Hospital and Medical Center; Investigator for Barrow Neurology Clinics; Director, NARCOMS Project for Consortium of MS Centers

Denise I Campagnolo, MD, MS is a member of the following medical societies: Alpha Omega Alpha, American Association of Neuromuscular and Electrodiagnostic Medicine, American Paraplegia Society, Association of Academic Physiatrists, and Consortium of Multiple Sclerosis Centers

Disclosure: Teva Neuroscience Honoraria Speaking and teaching; Serono-Pfizer Honoraria Speaking and teaching; Genzyme Corporation Grant/research funds investigator; Biogen Idec Grant/research funds investigator; Genentech, Inc Grant/research funds investigator; Eli Lilly & Company Grant/research funds investigator; Novartis investigator; MSDx LLC Grant/research funds investigator; BioMS Technology Corp Grant/research funds investigator; Avanir Pharmaceuticals Grant/research funds investigator

References
  1. Gonzalez H, Ottervald J, Nilsson KC, et al. Identification of novel candidate protein biomarkers for the post-polio syndrome - implications for diagnosis, neurodegeneration and neuroinflammation. J Proteomics. Jan 30 2009;71(6):670-81. [Medline].

  2. Bouza C, Munoz A, Amate JM. Postpolio syndrome: a challenge to the health-care system. Health Policy. Jan 2005;71(1):97-106. [Medline].

  3. Fordyce CB, Gagne D, Jalili F, et al. Elevated serum inflammatory markers in post-poliomyelitis syndrome. J Neurol Sci. Aug 15 2008;271(1-2):80-6. [Medline].

  4. Stoelb BL, Carter GT, Abresch RT, et al. Pain in persons with postpolio syndrome: frequency, intensity, and impact. Arch Phys Med Rehabil. Oct 2008;89(10):1933-40. [Medline].

  5. Chang KH, Lai CH, Chen SC, Hsiao WT, Liou TH, Lee CM. Body composition assessment in taiwanese individuals with poliomyelitis. Arch Phys Med Rehabil. Jul 2011;92(7):1092-7. [Medline].

  6. Correa JC, Rocco CC, de Andrade DV, et al. Electromyographic and neuromuscular analysis in patients with post-polio syndrome. Electromyogr Clin Neurophysiol. Nov-Dec 2008;48(8):329-33. [Medline].

  7. Tersteeg IM, Koopman FS, Stolwijk-Swuste JM, Beelen A, Nollet F. A 5-year longitudinal study of fatigue in patients with late-onset sequelae of poliomyelitis. Arch Phys Med Rehabil. Jun 2011;92(6):899-904. [Medline].

  8. Skough K, Krossen C, Heiwe S, et al. Effects of resistance training in combination with coenzyme Q10 supplementation in patients with post-polio: a pilot study. J Rehabil Med. Oct 2008;40(9):773-5. [Medline].

  9. Gonzalez H, Sunnerhagen KS, Sjoberg I, et al. Intravenous immunoglobulin for post-polio syndrome: a randomised controlled trial. Lancet Neurol. Jun 2006;5(6):493-500. [Medline].

  10. On AY, Oncu J, Uludag B, et al. Effects of lamotrigine on the symptoms and life qualities of patients with post polio syndrome: a randomized, controlled study. NeuroRehabilitation. 2005;20(4):245-51. [Medline].

  11. Agre JC. Symposium on post-polio syndrome. Disabil Rehabil. Jun 1996;18(6):305-6. [Medline].

  12. Agre JC. The role of exercise in the patient with post-polio syndrome. Ann N Y Acad Sci. May 25 1995;753:321-34. [Medline].

  13. Bartfeld H, Ma D. Recognizing post-polio syndrome. Hosp Pract (Off Ed). May 15 1996;31(5):95-7, 101-3, 107 passim. [Medline].

  14. Bruno RL. Post-polio syndrome. Neurology. Nov 1996;47(5):1359-60. [Medline].

  15. Dalakas MC. Pathogenetic mechanisms of post-polio syndrome: morphological, electrophysiological, virological, and immunological correlations. Ann N Y Acad Sci. May 25 1995;753:167-85. [Medline].

  16. Dalakas MC. The post-polio syndrome as an evolved clinical entity. Definition and clinical description. Ann N Y Acad Sci. May 25 1995;753:68-80. [Medline].

  17. Dinsmore S, Dambrosia J, Dalakas MC. A double-blind, placebo-controlled trial of high-dose prednisone for the treatment of post-poliomyelitis syndrome. Ann N Y Acad Sci. May 25 1995;753:303-13. [Medline].

  18. Einarsson G, Grimby G. Strengthening exercise program in post-polio subjects. Birth Defects Orig Artic Ser. 1987;23(4):275-83. [Medline].

  19. Feldman RM, Soskolne CL. The use of nonfatiguing strengthening exercises in post-polio syndrome. Birth Defects Orig Artic Ser. 1987;23(4):335-41. [Medline].

  20. Halstead LS, Rossi CD. Post-polio syndrome: clinical experience with 132 consecutive outpatients. Birth Defects Orig Artic Ser. 1987;23(4):13-26. [Medline].

  21. Horemans HL, Nollet F, Beelen A. Pyridostigmine in postpolio syndrome: no decline in fatigue and limited functional improvement. J Neurol Neurosurg Psychiatry. Dec 2003;74(12):1655-61. [Medline].

  22. Illa I, Leon-Monzon M, Agboatwalla M. Antiganglioside antibodies in patients with acute polio and post-polio syndrome. Ann N Y Acad Sci. May 25 1995;753:374-7. [Medline].

  23. Julien J, Leparc-Goffart I, Lina B. Postpolio syndrome: poliovirus persistence is involved in the pathogenesis. J Neurol. Jun 1999;246(6):472-6. [Medline].

  24. Maselli RA, Wollmann R, Roos R. Function and ultrastructure of the neuromuscular junction in post-polio syndrome. Ann N Y Acad Sci. May 25 1995;753:129-37. [Medline].

  25. Okumura H, Kurland LT, Waring SC. Amyotrophic lateral sclerosis and polio: is there an association?. Ann N Y Acad Sci. May 25 1995;753:245-56. [Medline].

  26. Diseases of the motor unit. In: DeLisa J, Gans B, eds. Rehabilitation Medicine: Principles and Practice. 3rd ed. Philadelphia, Pa: Lippincott-Raven; 1998:1554-6.

  27. Ring D, Vaccaro AR, Scuderi G. An association between the flat back and postpolio syndromes: a report of three cases. Arch Phys Med Rehabil. Mar 1997;78(3):324-6. [Medline].

  28. Semino-Mora C, Dalakas MC. Rimmed vacuoles with beta-amyloid and ubiquitinated filamentous deposits in the muscles of patients with long-standing denervation (postpoliomyelitis muscular atrophy): similarities with inclusion body myositis. Hum Pathol. Oct 1998;29(10):1128-33. [Medline].

  29. Shetty KR, Gupta KL, Agre JC. Effect of human growth hormone on muscle function in post-polio syndrome. Ann N Y Acad Sci. May 25 1995;753:386-9. [Medline].

  30. Sliwa J. Postpolio syndrome and rehabilitation. Am J Phys Med Rehabil. Dec 2004;83(12):909. [Medline].

  31. Sonies BC, Dalakas MC. Progression of oral-motor and swallowing symptoms in the post-polio syndrome. Ann N Y Acad Sci. May 25 1995;753:87-95. [Medline].

  32. Spector SA, Gordon PL, Yildiz E. Effect of strength training in patients with post-polio syndrome. A preliminary report. Ann N Y Acad Sci. May 25 1995;753:402-4. [Medline].

  33. Stein DP, Dambrosia JM, Dalakas MC. A double-blind, placebo-controlled trial of amantadine for the treatment of fatigue in patients with the post-polio syndrome. Ann N Y Acad Sci. May 25 1995;753:296-302. [Medline].

  34. Thorsteinsson G. Management of postpolio syndrome. Mayo Clin Proc. Jul 1997;72(7):627-38. [Medline].

  35. Trojan DA, Cashman NR. Anticholinesterases in post-poliomyelitis syndrome. Ann N Y Acad Sci. May 25 1995;753:285-95. [Medline].

  36. Trojan DA, Collet JP, Shapiro S. A multicenter, randomized, double-blinded trial of pyridostigmine in postpolio syndrome. Neurology. Oct 12 1999;53(6):1225-33. [Medline].

  37. van Kralingen KW, Ivanyi B, van Keimpema AR. Sleep complaints in postpolio syndrome. Arch Phys Med Rehabil. Jun 1996;77(6):609-11. [Medline].

  38. Windebank AJ, Litchy WJ, Daube JR. Lack of progression of neurologic deficit in survivors of paralytic polio: a 5-year prospective population-based study. Neurology. Jan 1996;46(1):80-4. [Medline].

  39. Windebank AJ, Litchy WJ, Daube JR. Prospective cohort study of polio survivors in Olmsted County, Minnesota. Ann N Y Acad Sci. May 25 1995;753:81-6. [Medline].

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