Coccyx Pain Medication

  • Author: Patrick M Foye, MD; Chief Editor: Consuelo T Lorenzo, MD   more...
 
Updated: Jan 23, 2012
 

Medication Summary

As previously stated, early interventions (eg, oral medications, injections, physical therapy) are presumed to decrease the chance that acute coccydynia will become chronic.

Once the coccyx pain has become chronic (persisting for more than 3-6 mo), it may be less likely to resolve by natural recovery alone, more likely to continue indefinitely, more likely to be resistant to treatment, and more likely to require a multimodal treatment approach (eg, oral medications combined with local injections).

Nonsteroidal anti-inflammatory drugs, analgesics, and anticonvulsants can all be used to manage pain in patients with coccydynia.

Next

Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)

Class Summary

NSAIDs have analgesic, anti-inflammatory, and antipyretic activities. The mechanism of action may be inhibition of cyclo-oxygenase (COX) activity and prostaglandin synthesis. Other mechanisms may include inhibition of leukotriene synthesis, lysosomal enzyme release, lipoxygenase activity, neutrophil aggregation, and various cell membrane functions.

Ibuprofen (Advil, Motrin, Caldolor, Neoprofen, Ibu)

 

This is a classic anti-inflammatory used for patients with mild to moderate pain. It inhibits inflammatory reactions and pain by decreasing prostaglandin synthesis.

Previous
Next

Analgesics, Other

Class Summary

Pain control is essential to quality patient care. Analgesics ensure patient comfort and have sedating properties that may be beneficial for patients who experience pain.

Acetaminophen (Aspirin Free Anacin, FeverAll, Tylenol, Mapap)

 

Acetaminophen is a first-line medication for treating pain in patients with documented hypersensitivity to aspirin or NSAIDs, with upper GI disease, or who are taking oral anticoagulants.

It is effective in relieving mild to moderate acute pain; however, acetaminophen has no peripheral anti-inflammatory effects. It may be preferred in elderly patients because of fewer GI and renal side effects.

Tramadol (Ultram, Ryzolt, Rybix ODT)

 

Tramadol inhibits ascending pain pathways, altering the patient's perception of and response to pain. It inhibits the reuptake of norepinephrine and serotonin.

Pregabalin (Lyrica)

 

Pregabalin is a structural derivative of gamma-aminobutyric acid (GABA); its mechanism of action is unknown. Pregabalin binds with high affinity to the alpha2-delta site (a calcium channel subunit). It reduces the calcium-dependent release of several neurotransmitters in vitro, possibly by modulating calcium channel function. Pregabalin has been approved by the US Food and Drug Administration (FDA) for the treatment of neuropathic pain associated with diabetic peripheral neuropathy or postherpetic neuralgia.

Fentanyl citrate (Duragesic, Abstral, Actiq, Fentora, Onsolis)

 

Fentanyl citrate is a synthetic opioid that has 75-200 times more potency and a much shorter half-life than morphine sulfate. It has fewer hypotensive effects than morphine and is safer in patients with hyperactive airway disease because of minimal or no associated histamine release. By itself, fentanyl citrate causes little cardiovascular compromise, although the addition of benzodiazepines or other sedatives may result in decreased cardiac output and blood pressure.

Fentanyl citrate is highly lipophilic and protein-bound. Prolonged exposure to it leads to accumulation of the drug in fat and delays the weaning process. Consider continuous infusion because of the medication's short half-life.

The parenteral form is the drug of choice for conscious-sedation analgesia. Fentanyl citrate is ideal for analgesic action of short duration during anesthesia and the immediate postoperative period. It is an excellent choice for pain management and sedation with short duration (30-60 min) and is easy to titrate. The drug's effects are easily and quickly reversed by naloxone.

After the initial parenteral dose of fentanyl citrate, subsequent parenteral doses should not be titrated more frequently than every 3 or 6 hours thereafter.

The transdermal form is used only for chronic pain conditions in opioid-tolerant patients. When using the transdermal dosage form, most patients are controlled with 72-hour dosing intervals; however, some patients require dosing intervals of 48 hours.

Oxycodone (OxyContin, Roxicodone)

 

Oxycodone is indicated for the relief of moderate to severe pain.

Oxycodone and acetaminophen (Percocet, Roxicet, Endocet, Primlev, Tylox)

 

This drug combination is indicated for the relief of moderate to severe pain.

Previous
Next

Anticonvulsants, Other

Class Summary

These are used as adjuvants for neuropathic pain.

Gabapentin (Neurontin)

 

Gabapentin is a membrane stabilizer. A structural analogue of the inhibitory neurotransmitter GABA, gabapentin paradoxically is thought not to exert an effect on GABA receptors. It appears to exert its action via the alpha2-delta1 and alpha2-delta2 auxiliary subunits of voltage-gated calcium channels.

Gabapentin is used to manage pain and provide sedation in neuropathic pain. Titration to effect can take place over several days (300mg on day 1, 300mg twice on day 2, and 300 mg 3 times on day 3).

Previous
 
Contributor Information and Disclosures
Author

Patrick M Foye, MD  Associate Professor of Physical Medicine and Rehabilitation, Co-Director of Musculoskeletal Fellowship, Co-Director of Back Pain Clinic, Director of Coccyx Pain Service (Tailbone Pain Service: www.TailboneDoctor.com), University of Medicine and Dentistry of New Jersey, New Jersey Medical School

Patrick M Foye, MD is a member of the following medical societies: American Academy of Physical Medicine and Rehabilitation, American Association of Neuromuscular and Electrodiagnostic Medicine, Association of Academic Physiatrists, and International Spine Intervention Society

Disclosure: Nothing to disclose.

Coauthor(s)

Charles J Buttaci, DO, PT  Pain Management, Northeast Orthopedics

Charles J Buttaci, DO, PT is a member of the following medical societies: American Academy of Physical Medicine and Rehabilitation, American Osteopathic College of Physical Medicine and Rehabilitation, and International Spine Intervention Society

Disclosure: Nothing to disclose.

Matthew Kirk Sorensen  University of Medicine and Dentistry of New Jersey-New Jersey Medical School

Matthew Kirk Sorensen, is a member of the following medical societies: Society for Developmental Biology

Disclosure: Nothing to disclose.

Chief Editor

Consuelo T Lorenzo, MD  Physiatrist, Department of Physical Medicine and Rehabilitation, Alegent Health Immanuel Rehabilitation Center

Consuelo T Lorenzo, MD is a member of the following medical societies: American Academy of Physical Medicine and Rehabilitation

Disclosure: Nothing to disclose.

Additional Contributors

Michael T Andary, MD, MS Professor, Residency Program Director, Department of Physical Medicine and Rehabilitation, Michigan State University College of Osteopathic Medicine

Michael T Andary, MD, MS is a member of the following medical societies: American Academy of Physical Medicine and Rehabilitation, American Association of Neuromuscular and Electrodiagnostic Medicine, American Medical Association, and Association of Academic Physiatrists

Disclosure: Allergan Honoraria Speaking and teaching; Pfizer Honoraria Speaking and teaching

Robert L Sheridan, MD Assistant Chief of Staff, Chief of Burn Surgery, Shriners Burns Hospital; Associate Professor of Surgery, Department of Surgery, Division of Trauma and Burns, Massachusetts General Hospital and Harvard Medical School

Robert L Sheridan, MD is a member of the following medical societies: American Academy of Pediatrics, American Association for the Surgery of Trauma, American Burn Association, and American College of Surgeons

Disclosure: Nothing to disclose.

Francisco Talavera, PharmD, PhD Adjunct Assistant Professor, University of Nebraska Medical Center College of Pharmacy; Editor-in-Chief, Medscape Drug Reference

Disclosure: Medscape Salary Employment

Dev Sinha, MD Resident Physician, Department of Physical Medicine and Rehabilitation, University of Pennsylvania Health Systems

Disclosure: Nothing to disclose.

Acknowledgments

Dr. Foye acknowledges and appreciates the numerous patients with coccyx pain who have traveled—often substantial distances—to see him over the years. Much has been learned by listening to descriptions of their symptoms and to their stories, by discovering how suffering from coccyx pain impacts the quality of their lives, and by analyzing their favorable responses to nonsurgical treatment. Their substantial contributions to the coccydynia knowledge base have helped in the treatment of many subsequent patients with coccyx pain, not only in Dr. Foye's practice, but (through his publications in this area) elsewhere as well. Dr. Foye finds it to be a gratifying privilege to help so many of these patients find relief.

Evish Kamrava, 4th year medical student, St. George's University School of Medicine, Class of 2009, assisted with the 2008 revision of this manuscript.

References
  1. Howorth B. The painful coccyx. Clin Orthop. 1959;14:145-60.

  2. Wray CC, Easom S, Hoskinson J. Coccydynia. Aetiology and treatment. J Bone Joint Surg Br. Mar 1991;73(2):335-8. [Medline]. [Full Text].

  3. Nathan ST, Fisher BE, Roberts CS. Coccydynia: a review of pathoanatomy, aetiology, treatment and outcome. J Bone Joint Surg Br. Dec 2010;92(12):1622-7. [Medline].

  4. Foye PM. Stigma against patients with coccyx pain. Pain Med. Dec 2010;11(12):1872. [Medline].

  5. Richette P, Maigne JY, Bardin T. Coccydynia related to calcium crystal deposition. Spine. Aug 1 2008;33(17):E620-3. [Medline].

  6. Foye PM. Coccydynia (coccyx pain) caused by chordoma. Int Orthop. Jun 2007;31(3):427. [Medline]. [Full Text].

  7. Foye PM. Finding the causes of coccydynia (coccygeal pain). J Bone Joint Surg Br. Jan 18 2007;[Full Text].

  8. Maigne JY, Doursounian L, Chatellier G. Causes and mechanisms of common coccydynia: role of body mass index and coccygeal trauma. Spine. Dec 1 2000;25(23):3072-9. [Medline].

  9. Foye PM. A new diagnostic test for coccyx pain (tailbone pain): seated MRI. Am J Phys Med Rehabil. Mar 2008;87(3):S36.

  10. Balain B, Eisenstein SM, Alo GO, et al. Coccygectomy for coccydynia: case series and review of literature. Spine. Jun 1 2006;31(13):E414-20. [Medline].

  11. [Best Evidence] Maigne JY, Chatellier G, Faou ML, et al. The treatment of chronic coccydynia with intrarectal manipulation: a randomized controlled study. Spine. Aug 15 2006;31(18):E621-7. [Medline].

  12. Foye PM, Schoenherr L, Kim JH. Coccydynia (coccyx pain) after colonoscopy. Am J Phys Med Rehabil. Mar 2008;87(3):S36.

  13. Maigne JY, Guedj S, Fautrel B. [Coccygodynia: value of dynamic lateral x-ray films in sitting position]. Rev Rhum Mal Osteoartic. Nov 30 1992;59(11):728-31. [Medline].

  14. Maigne JY, Tamalet B. Standardized radiologic protocol for the study of common coccygodynia and characteristics of the lesions observed in the sitting position. Clinical elements differentiating luxation, hypermobility, and normal mobility. Spine. Nov 15 1996;21(22):2588-93. [Medline].

  15. Wood KB, Mehbod AA. Operative treatment for coccygodynia. J Spinal Disord Tech. Dec 2004;17(6):511-5. [Medline].

  16. Kerr EE, Benson D, Schrot RJ. Coccygectomy for chronic refractory coccygodynia: clinical case series and literature review. J Neurosurg Spine. May 2011;14(5):654-63. [Medline].

  17. Alo GO, Eisenstein SM, Darby A. The sacro-coccygeal joint in coccydynia. J Bone Joint Surg Br. 1998;80-B(2S):196.

  18. Foye PM. Reasons to delay or avoid coccygectomy for coccyx pain. Injury. Nov 2007;38(11):1328-9. [Medline].

  19. Hodges SD, Eck JC, Humphreys SC. A treatment and outcomes analysis of patients with coccydynia. Spine J. Mar-Apr 2004;4(2):138-40. [Medline].

  20. Pennekamp PH, Kraft CN, Stütz A, et al. Coccygectomy for coccygodynia: does pathogenesis matter?. J Trauma. Dec 2005;59(6):1414-9. [Medline].

  21. Borgia CA. Coccydynia: its diagnosis and treatment. Mil Med. Apr 1964;129:335-8. [Medline].

  22. Foye PM. Ganglion impar blocks for chronic pelvic and coccyx pain. Pain Physician. Nov 2007;10(6):780-1. [Medline]. [Full Text].

  23. Foye PM. Safe ganglion Impar blocks for visceral and coccyx pain. Techniques in Regional Anesthesia and Pain Management. April 2008;12(2):122-123.

  24. Foye PM. Ganglion impar blocks via coccygeal versus sacrococcygeal joints. Reg Anesth Pain Med. May-Jun 2008;33(3):279-80. [Medline].

  25. Foye PM. Ganglion impar injection techniques for coccydynia (coccyx pain) and pelvic pain. Anesthesiology. May 2007;106(5):1062-3; author reply 1063. [Medline].

  26. Foye PM. New approaches to ganglion impar blocks via coccygeal joints. Reg Anesth Pain Med. May-Jun 2007;32(3):269. [Medline].

  27. Foye PM. Treatment of tailbone pain (coccyx pain, coccydynia) by injection of local anesthetic to the ganglion Impar. www.Tailbone.info. Available at http://tailbone.info/ganglionimparinjections.html. Accessed Jul 14 2007.

  28. Oh CS, Chung IH, Ji HJ, et al. Clinical implications of topographic anatomy on the ganglion impar. Anesthesiology. Jul 2004;101(1):249-50. [Medline].

  29. Buttaci CJ, Foye PM, Stitik TP, et al. Coccydynia successfully treated with ganglion impar blocks: a case series. Am J Phys Med Rehabil. Mar 2005;84(3):218.

  30. Kuthuru M, Kabbara AI, Oldenburg P, et al. Coccygeal pain relief after transsacrococcygeal block of the ganglion Impar under fluoroscopy: a case report. Arch Phys Med Rehabil. Sep 2003;84(9):E24.

  31. Kabbara AI. Transsacrococcygeal ganglion impar block for postherpetic neuralgia. Anesthesiology. Jul 2005;103(1):211-2. [Medline].

  32. Atim A, Ergin A, Bilgiç S, Deniz S, Kurt E. Pulsed radiofrequency in the treatment of coccygodynia. Agri. Jan 2011;23(1):1-6. [Medline].

  33. Plancarte R, Amescua C, Patt RB, et al. Presacral blockade of the ganglion of Walther (ganglion Impar). Anesthesiology. 1990;73(3a):A751.

  34. Foye PM, Buttaci CJ, Stitik TP, et al. Successful injection for coccyx pain. Am J Phys Med Rehabil. Sep 2006;85(9):783-4. [Medline].

  35. Reig E, Abejón D, Del Pozo C, et al. Thermocoagulation of the ganglion impar or ganglion of walther: description of a modified approach. Preliminary results in chronic, nononcological pain. Pain Pract. Jun 2005;5(2):103-10. [Medline].

Previous
Next
 
Lateral view of the pelvis and coccyx. The bracket shows the area of focus for radiographs that would provide a coned-down view of mainly the coccyx and distal sacrum. A more common lateral view would often also include larger bony structures, such as the lumbar spine and femur, all of which would make it difficult to optimize visualization of the small bones of the coccyx. In patients with coccyx pain, these coned-down, lateral views of the coccyx can provide important diagnostic information. Coned-down images obtained in the weight-bearing (seated) position can be compared with those obtained in a non–weight-bearing position (eg, side lying), thus allowing assessment for dynamic instability (eg, dislocations that occur only while seated).
Coccyx pain (coccydynia, or tailbone pain) is typically worse when the patient is sitting. Often, the pain is even worse when sitting leaning slightly backward, since this increases the weight bearing on the coccyx, as shown in this image. Dynamic radiographs of the coccyx involve obtaining coned-down (focused) views of the coccyx while the patient is seated (eg, in his or her most painful position). Often, this involves having the patient lean backward 0-40°, depending on the symptoms. Radiographs obtained in this position are compared with those obtained in a non–weight-bearing position (eg, side lying) to assess for instability or dislocations in the seated position.
Patients with a painful coccyx often find it more comfortable to sit leaning slightly forward, as shown in this image. This forward-leaning position minimizes any weight bearing on the coccyx itself and thus minimizes the exacerbation of coccyx pain. As shown, when a patient sits leaning forward, most of the weight bearing occurs bilaterally through the inferior ischial regions of the pelvis and the posterior thigh (femur) regions.
 
 
 
All material on this website is protected by copyright, Copyright © 1994-2012 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.

DISCLAIMER: The content of this Website is not influenced by sponsors. The site is designed primarily for use by qualified physicians and other medical professionals. The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The information provided here is for educational and informational purposes only. In no way should it be considered as offering medical advice. Please check with a physician if you suspect you are ill.