eMedicine Specialties > Physical Medicine and Rehabilitation > Muscle Pain Syndromes
Myofascial Pain
Updated: Aug 26, 2009
Introduction
Background
Myofascial pain (MP) is a common, painful disorder that is responsible for many pain clinic visits. MP can affect any skeletal muscles in the body. Skeletal muscle accounts for approximately 50% of body weight, and approximately 400 muscles make up the body. MP is responsible for many cases of chronic musculoskeletal pain.
MP can cause local or referred pain, tightness, tenderness, popping and clicking, stiffness and limitation of movement, autonomic phenomena, local twitch response (LTR) in the affected muscle, and muscle weakness without atrophy. Trigger points (TrPs), which cause referred pain in characteristic areas for specific muscles, restricted range of motion (ROM), and a visible or palpable LTR to local stimulation, are classic signs of MP. Over 70% of TrPs correspond to acupuncture points used to treat pain.1
An active TrP is an area that refers pain to a remote area in a defined pattern when local stimulation is applied. Satellite TrPs appear in response to a primary, active TrP and usually disappear after the primary TrP has been inactivated. Latent TrPs cause stiffness and limitation of ROM but no pain. Frequently, they are found in asymptomatic individuals.
Although MP and fibromyalgia have some overlapping features, they are separate entities; fibromyalgia is a widespread pain problem, not a regional condition caused by specific TrPs.
Pathophysiology
A taut band in a muscle may be necessary as a precursor to the development of a trigger point (TrP). Taut bands are common in asymptomatic individuals, but patients with them are more likely to develop a TrP. A latent TrP can develop into an active TrP for a number of reasons. Psychological stress, muscle tension, and physical factors, such as poor posture, can cause a latent TrP to become active.
The pathophysiology of myofascial pain is not well understood. Current research supports sensitization of low-threshold, mechanosensitive afferents associated with dysfunctional motor endplates in the area of the TrPs projecting to sensitized dorsal horn neurons in the spinal cord. Pain referred from TrPs, as well as LTRs, may be mediated through the spinal cord after stimulation of a sensitive locus.2,3
Frequency
United States
Myofascial pain (MP) is extremely common, and almost everyone develops a trigger point (TrP) at some time. In the US, 14.4% of the general population suffers from chronic musculoskeletal pain. Approximately 21-93% of patients with regional pain complaints have MP. Studies have demonstrated that 25-54% of asymptomatic individuals have latent TrPs.
Mortality/Morbidity
Myofascial pain (MP) is not a fatal condition, but it can cause significant reduction in quality of life (QOL) and is a major cause of time lost from work. Costs associated with MP sap millions, perhaps billions, of dollars from the economy.
Race
No racial differences in the incidence of myofascial pain have been described in the literature.
Sex
Myofascial pain is distributed equally between men and women.
Age
Myofascial trigger points (TrPs) can be found in persons of all ages, even infants. The likelihood of developing active TrPs increases with age and activity level into the middle years. Sedentary individuals are more prone to develop active TrPs than are individuals who exercise vigorously on a daily basis.
Clinical
History
Patients with myofascial pain usually report regionalized aching and poorly localized pain in the muscles and joints. They also may report sensory disturbances, such as numbness in a characteristic of distribution. The type of pain felt is characteristic of the muscle involved. An acute onset may occur after a specific event or trauma (eg, moving quickly in an awkward position), while chronic pain may result from poor posture or overuse.4 Patients may note disturbed sleep. Persons with cervical and periscapular myofascial pain may have difficulty finding a comfortable sleeping position. They may or may not be aware of muscle weakness in the affected muscles and may have a tendency to drop things.
Physical
A skilled examiner can provide accurate diagnosis of myofascial pain (MP). Unfortunately, most medical school and residency training programs do not adequately cover this common condition.5 Locating trigger points (TrPs) is the most important part of the physical examination. TrPs tend to occur in characteristic locations in individual muscles. The book Travell and Simons' Myofascial Pain and Dysfunction: The Trigger Point Manual is considered the criterion standard reference on locating and treating TrPs.2,6,7
When the TrP is located, the patient typically has a positive jump sign when local pressure is applied over the area; the jump sign should not be confused with an LTR. The jump sign simply means that the patient jumps from pain or discomfort in the area that has been palpated. Apply a consistent amount of pressure to the area, because applying too much pressure can elicit pain in nearly all individuals. A pressure algometer (ie, pressure threshold meter) or palpatometer can be used to standardize the amount of pressure applied.8
A taut band is found in the muscle, either by palpation or by needle penetration. It can be distinguished by palpating or by dragging the fingers perpendicular to the muscle fibers. A localized knot or a tight, ropy area is noted. Patients report that the area is extremely tender when palpated. A localized flinching in the area of the muscle being palpated or an LTR may be noted in active TrPs, as well as in latent ones. Palpation or insertion of a needle into the TrP causes reproduction of the patient's pain and, frequently, sensory complaints. Palpation of either an active or a latent TrP causes referred pain in a characteristic area for each muscle, a phenomenon described in the above-mentioned TrP manual. Sensory disturbance (eg, paresthesias, dysesthesias, localized skin tenderness) may be noted in the same area where pain may be referred. Autonomic phenomena also may be elicited (eg, sweating, piloerection, temperature changes).
Essential criteria for identifying an active or latent TrP include the following:
- Palpable taut band if the muscle is accessible
- Exquisite spot tenderness of a nodule in a taut band
- Patient's recognition of current pain complaint by pressure on the tender nodule
- Painful limit to full ROM stretch of the involved muscle
Confirmatory observations include the following:
- Visual or tactile identification of an LTR
- Imaging of an LTR induced by needle penetration of a tender nodule
- Pain or altered sensation on compression of a tender nodule, in the distribution expected from a TrP in that muscle
- Electromyographic demonstration of spontaneous electrical activity (SEA) that is characteristic of active loci in the tender nodule of a taut band
- Lowered skin resistance to electrical current - This has been found over active TrPs when compared with surrounding tissue and may be useful in localizing TrPs. Skin resistance normalizes after the treatment of TrPs.
Causes
Several factors contribute to myofascial pain (MP). Abnormal stresses on the muscles from sudden stress on shortened muscles, leg-length discrepancies, or skeletal asymmetry are thought to be common causes of MP. Poor posture also may cause MP. In addition, the assumption of a static position for a prolonged period of time has been implicated in the condition. Anemia and low levels of calcium, potassium, iron, and vitamins C, B-1, B-6, and B-12 are believed to play a role. Chronic infections and sleep deprivation have been cited as causative factors, as have radiculopathy, visceral diseases, and depression. Hypothyroidism, hyperuricemia, and hypoglycemia also have been implicated in MP. The pathogenesis likely has a central mechanism, with peripheral clinical manifestations.
More on Myofascial Pain |
Overview: Myofascial Pain |
| Differential Diagnoses & Workup: Myofascial Pain |
| Treatment & Medication: Myofascial Pain |
| Follow-up: Myofascial Pain |
| References |
| Further Reading |
| Next Page » |
References
Dorsher PT. Myofascial referred-pain data provide physiologic evidence of acupuncture meridians. J Pain. Jul 2009;10(7):723-31. [Medline].
McPartland JM. Travell trigger points--molecular and osteopathic perspectives. J Am Osteopath Assoc. Jun 2004;104(6):244-9. [Medline]. [Full Text].
Hong CZ, Simons DG. Pathophysiologic and electrophysiologic mechanisms of myofascial trigger points. Arch Phys Med Rehabil. Jul 1998;79(7):863-72. [Medline].
Gerwin RD. A review of myofascial pain and fibromyalgia--factors that promote their persistence. Acupunct Med. Sep 2005;23(3):121-34. [Medline].
Graff-Radford SB. Myofascial pain: diagnosis and management. Curr Pain Headache Rep. Dec 2004;8(6):463-7. [Medline].
Simons DG, Travell JG, Simons LS. Travell and Simons' Myofascial Pain and Dysfunction: The Trigger Point Manual. 2nd ed. Baltimore, Md: Williams & Wilkins; 1999.
Gerwin RD, Dommerholt J, Shah JP. An expansion of Simons' integrated hypothesis of trigger point formation. Curr Pain Headache Rep. Dec 2004;8(6):468-75. [Medline].
Myburgh C, Larsen AH, Hartvigsen J. A systematic, critical review of manual palpation for identifying myofascial trigger points: evidence and clinical significance. Arch Phys Med Rehabil. Jun 2008;89(6):1169-76. [Medline].
Hameroff SR, Crago BR, Blitt CD, et al. Comparison of bupivacaine, etidocaine, and saline for trigger-point therapy. Anesth Analg. Oct 1981;60(10):752-5. [Medline].
Hong CZ. Lidocaine injection versus dry needling to myofascial trigger point. The importance of the local twitch response. Am J Phys Med Rehabil. Jul-Aug 1994;73(4):256-63. [Medline].
Venâncio Rde A, Alencar FG, Zamperini C. Different substances and dry-needling injections in patients with myofascial pain and headaches. Cranio. Apr 2008;26(2):96-103. [Medline].
Wreje U, Brorsson B. A multicenter randomized controlled trial of injections of sterile water and saline for chronic myofascial pain syndromes. Pain. Jun 1995;61(3):441-4. [Medline].
Aoki KR. Evidence for antinociceptive activity of botulinum toxin type A in pain management. Headache. Jul-Aug 2003;43 Suppl 1:S9-15. [Medline].
Lang AM. Botulinum toxin therapy for myofascial pain disorders. Curr Pain Headache Rep. Oct 2002;6(5):355-60. [Medline].
Jeynes LC, Gauci CA. Evidence for the use of botulinum toxin in the chronic pain setting--a review of the literature. Pain Pract. Jul-Aug 2008;8(4):269-76. [Medline].
Cheshire WP, Abashian SW, Mann JD. Botulinum toxin in the treatment of myofascial pain syndrome. Pain. Oct 1994;59(1):65-9. [Medline].
Affaitati G, Fabrizio A, Savini A, et al. A randomized, controlled study comparing a lidocaine patch, a placebo patch, and anesthetic injection for treatment of trigger points in patients with myofascial pain syndrome: evaluation of pain and somatic pain thresholds. Clin Ther. Apr 2009;31(4):705-20. [Medline].
Gam AN, Warming S, Larsen LH, et al. Treatment of myofascial trigger-points with ultrasound combined with massage and exercise--a randomised controlled trial. Pain. Jul 1998;77(1):73-9. [Medline].
Lee SH, Chen CC, Lee CS, et al. Effects of needle electrical intramuscular stimulation on shoulder and cervical myofascial pain syndrome and microcirculation. J Chin Med Assoc. Apr 2008;71(4):200-6. [Medline].
Srbely JZ, Dickey JP, Lowerison M, et al. Stimulation of myofascial trigger points with ultrasound induces segmental antinociceptive effects: a randomized controlled study. Pain. May 26 2008;[Medline].
Flor H, Birbaumer N. Comparison of the efficacy of electromyographic biofeedback, cognitive- behavioral therapy, and conservative medical interventions in the treatment of chronic musculoskeletal pain. J Consult Clin Psychol. Aug 1993;61(4):653-8. [Medline].
Birch S, Jamison RN. Controlled trial of Japanese acupuncture for chronic myofascial neck pain: assessment of specific and nonspecific effects of treatment. Clin J Pain. Sep 1998;14(3):248-55. [Medline].
Leite FM, Atallah AN, El Dib R, et al. Cyclobenzaprine for the treatment of myofascial pain in adults. Cochrane Database Syst Rev. Jul 8 2009;CD006830. [Medline].
Bendtsen L, Jensen R, Olesen J. Qualitatively altered nociception in chronic myofascial pain. Pain. May-Jun 1996;65(2-3):259-64. [Medline].
Danto JB. Review of integrated neuromusculoskeletal release and the novel application of a segmental anterior/posterior approach in the thoracic, lumbar, and sacral regions. J Am Osteopath Assoc. Dec 2003;103(12):583-96. [Medline]. [Full Text].
Facco E, Ceccherelli F. Myofascial pain mimicking radicular syndromes. Acta Neurochir Suppl. 2005;92:147-50. [Medline].
Hsueh TC, Cheng PT, Kuan TS, et al. The immediate effectiveness of electrical nerve stimulation and electrical muscle stimulation on myofascial trigger points. Am J Phys Med Rehabil. Nov-Dec 1997;76(6):471-6. [Medline].
Saggini R, Giamberardino MA, Gatteschi L, et al. Myofascial pain syndrome of the peroneus longus: biomechanical approach. Clin J Pain. Mar 1996;12(1):30-7. [Medline].
Simons DG. Review of enigmatic MTrPs as a common cause of enigmatic musculoskeletal pain and dysfunction. J Electromyogr Kinesiol. Feb 2004;14(1):95-107. [Medline].
Further Reading
Related eMedicine topics:
Cervical Myofascial Pain
Fibromyalgia [Pediatrics: General Medicine]
Fibromyalgia [Physical Medicine and Rehabilitation]
Fibromyalgia [Rheumatology]
Massage, Traction, and Manipulation
Myofascial Pain in Athletes
Transcutaneous Electrical Nerve Stimulation
Keywords
myofascial pain, myofascial, trigger point, myofascial pain, myofascial pain syndrome, trigger point pain, chronic myofascial pain, trigger point therapy, myofascial trigger point, myofascial trigger, trigger point injections, trigger pain, pain and myofascial, musclehãrten, myogeloses, osteochondrosis, myofascitis
Overview: Myofascial Pain