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Hypothyroid Myopathy Follow-up

  • Author: Divakara Kedlaya, MBBS; Chief Editor: Stephen Kishner, MD, MHA  more...
Updated: Apr 07, 2015

Further Outpatient Care

See the list below:

  • Outpatient physical therapy is indicated.

Further Inpatient Care

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  • Some patients with hypothyroid myopathy may need a short stay in acute rehabilitation.

Inpatient & Outpatient Medications

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  • Continuation of thyroid supplementation is needed, with close monitoring of the levels. Once a normal value has been achieved (normal TSH), levels can be checked annually, unless the patient becomes pregnant or exacerbation of symptoms develops.


See the list below:

  • Patients with hypothyroid myopathy should be careful with regard to the use of cholesterol-reducing agents (ie, HMG CoA reductase inhibitors), such as statins.


With treatment, hypothyroidism has a good prognosis. An early diagnosis and the prompt introduction of thyroid supplemental treatment are needed. Complete resolution of weakness and other symptoms of hypothyroid myopathy may take several months to years of treatment.[13]

In a study of patients with endocrine disorder myopathies, Sharma et al found that out of 10 hypothyroid patients with apparent muscle dysfunction, 7 patients (70%) achieved resolution of muscle complaints after being treated for low T4 levels for an average period of 6.4 months.[31]

Contributor Information and Disclosures

Divakara Kedlaya, MBBS Clinical Associate Professor, Department of Physical Medicine and Rehabilitation, Loma Linda University School of Medicine; Medical Director, Physical Medicine and Rehabilitation and Pain Management, St Mary Corwin Medical Center

Divakara Kedlaya, MBBS is a member of the following medical societies: American Academy of Physical Medicine and Rehabilitation, Colorado Medical Society, American Association of Neuromuscular and Electrodiagnostic Medicine

Disclosure: Nothing to disclose.


Diana Echeverry, MD, MPH Assistant Professor, Department of Endocrinology, Charles Drew University of Medicine and Science

Disclosure: Nothing to disclose.

Specialty Editor Board

Francisco Talavera, PharmD, PhD Adjunct Assistant Professor, University of Nebraska Medical Center College of Pharmacy; Editor-in-Chief, Medscape Drug Reference

Disclosure: Received salary from Medscape for employment. for: Medscape.

Kat Kolaski, MD Assistant Professor, Departments of Orthopedic Surgery and Pediatrics, Wake Forest University School of Medicine

Kat Kolaski, MD is a member of the following medical societies: American Academy for Cerebral Palsy and Developmental Medicine, American Academy of Physical Medicine and Rehabilitation

Disclosure: Nothing to disclose.

Chief Editor

Stephen Kishner, MD, MHA Professor of Clinical Medicine, Physical Medicine and Rehabilitation Residency Program Director, Louisiana State University School of Medicine in New Orleans

Stephen Kishner, MD, MHA is a member of the following medical societies: American Academy of Physical Medicine and Rehabilitation, American Association of Neuromuscular and Electrodiagnostic Medicine

Disclosure: Nothing to disclose.

Additional Contributors

Elizabeth A Moberg-Wolff, MD Medical Director, Pediatric Rehabilitation Medicine Associates

Elizabeth A Moberg-Wolff, MD is a member of the following medical societies: American Academy for Cerebral Palsy and Developmental Medicine, American Academy of Physical Medicine and Rehabilitation

Disclosure: Nothing to disclose.

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