eMedicine Specialties > Physical Medicine and Rehabilitation > Plexopathy
Diabetic Lumbosacral Plexopathy: Follow-up
Updated: Oct 10, 2008
Follow-up
Further Inpatient Care
- Because of the sudden onset of functional loss, some patients with diabetic lumbosacral plexopathy may need to be transferred to a subacute rehabilitation facility or a convalescent home for several months, until they recover strength.
- Most patients are able to avoid inpatient care for this condition.
Further Outpatient Care
- Patients with diabetic lumbosacral plexopathy may derive further benefit from a course of outpatient physical therapy, achieving their maximum potential in terms of functional mobility and lower extremity strength.
Prognosis
- Good functional recovery within 12-24 months is expected in 60% of patients with diabetic lumbosacral plexopathy.
- Mild weakness, discomfort, and stiffness often persist for years.
- Occasional relapses can occur.
Patient Education
- The patient should be educated in the importance of good glycemic control in conjunction with proper diet and exercise.26
- During rehabilitation, the patient should be taught exercises to regain strength in the affected muscle groups, in order to improve functional recovery.
Related Medscape topics:
CME/CE Advances in Glucagon-like Peptides for the Treatment of Type 2 Diabetes
CME Managing Type 2 Diabetes: Developing Office-based Systems of Care
CME Weight Loss May Improve Glycemic Control and Blood Pressure in Type 2 Diabetes
Miscellaneous
Medicolegal Pitfalls
- Familiarity with the clinical setting of this condition and prompt diagnosis are medicolegally important. It is especially important to distinguish this disorder from compressive radiculopathy in order to avoid unnecessary surgery.
- Misdiagnosis can cause significant concerns for the patient and his/her family and could trigger a medicolegal lawsuit.
More on Diabetic Lumbosacral Plexopathy |
| Overview: Diabetic Lumbosacral Plexopathy |
| Differential Diagnoses & Workup: Diabetic Lumbosacral Plexopathy |
| Treatment & Medication: Diabetic Lumbosacral Plexopathy |
Follow-up: Diabetic Lumbosacral Plexopathy |
| References |
| « Previous Page |
References
Bruns L. Uberneuritsche lahmungen beim diabetes mellitus. Berl Klin Wochenschr. 1890;27:509-15.
Garland H. Diabetic amyotrophy. Br Med J. Nov 26 1955;2(4951):1287-90. [Medline]. [Full Text].
Asbury AK. Proximal diabetic neuropathy. Ann Neurol. Sep 1977;2(3):179-80. [Medline].
Locke S, Lawrence DG, Legg MA. Diabetic amyotrophy. Am J Med. Jun 1963;34:775-85. [Medline].
Sander HW, Chokroverty S. Diabetic amyotrophy: current concepts. Semin Neurol. Jun 1996;16(2):173-8. [Medline].
Tracy JA, Dyck PJ. The spectrum of diabetic neuropathies. Phys Med Rehabil Clin N Am. Feb 2008;19(1):1-26, v. [Medline].
Raff MC, Asbury AK. Ischemic mononeuropathy and mononeuropathy multiplex in diabetes mellitus. N Engl J Med. Jul 4 1968;279(1):17-21. [Medline].
Taylor BV, Dunne JW. Diabetic amyotrophy progressing to severe quadriparesis. Muscle Nerve. Oct 2004;30(4):505-9. [Medline].
Williams IR, Mayer RF. Subacute proximal diabetic neuropathy. Neurology. Feb 1976;26(2):108-16. [Medline].
Dyck PJ, Norell JE, Dyck PJ. Microvasculitis and ischemia in diabetic lumbosacral radiculoplexus neuropathy. Neurology. Dec 10 1999;53(9):2113-21. [Medline].
Harrison MJ, Casey EB. Diabetic amyotrophy. Br Med J. Jul 29 1972;3(5821):293. [Medline]. [Full Text].
Pascoe MK, Low PA, Windebank AJ. Subacute diabetic proximal neuropathy. Mayo Clin Proc. Dec 1997;72(12):1123-32. [Medline].
Kawamura N, Dyck PJ, Schmeichel AM, et al. Inflammatory mediators in diabetic and non-diabetic lumbosacral radiculoplexus neuropathy. Acta Neuropathol. Feb 2008;115(2):231-9. [Medline].
Dyck PJ, Windebank AJ. Diabetic and nondiabetic lumbosacral radiculoplexus neuropathies: new insights into pathophysiology and treatment. Muscle Nerve. Apr 2002;25(4):477-91. [Medline].
Casey EB, Harrison MJ. Diabetic amyotrophy: a follow-up study. Br Med J. Mar 11 1972;1(5801):656-9. [Medline]. [Full Text].
Bastron JA, Thomas JE. Diabetic polyradiculopathy: clinical and electromyographic findings in 105 patients. Mayo Clin Proc. Dec 1981;56(12):725-32. [Medline].
Barohn RJ, Sahenk Z, Warmolts JR. The Bruns-Garland syndrome (diabetic amyotrophy). Revisited 100 years later. Arch Neurol. Nov 1991;48(11):1130-5. [Medline].
Brown MJ, Asbury AK. Diabetic neuropathy. Ann Neurol. Jan 1984;15(1):2-12. [Medline].
Russell JW, Berent-Spillson A, Vincent AM, et al. Oxidative injury and neuropathy in diabetes and impaired glucose tolerance. Neurobiol Dis. Jun 2008;30(3):420-9. [Medline].
O'Neill BJ, Flanders AE, Escandon SL, et al. Treatable lumbosacral polyradiculitis masquerading as diabetic amyotrophy. J Neurol Sci. Oct 22 1997;151(2):223-5. [Medline].
Tataroglu C, Bicerol B, Kiylioglu N, et al. Proximal femoral conductions in patients with lumbosacral radiculoplexus neuropathy. Clin Neurol Neurosurg. Oct 2007;109(8):654-60. [Medline].
Subramony SH, Wilbourn AJ. Diabetic proximal neuropathy. Clinical and electromyographic studies. J Neurol Sci. Feb 1982;53(2):293-304. [Medline].
Fernandes Filho JA, Nathan BM, Palmert MR, et al. Diabetic amyotrophy in an adolescent responsive to intravenous immunoglobulin. Muscle Nerve. Dec 2005;32(6):818-20. [Medline].
Kawagashira Y, Watanabe H, Oki Y, et al. Intravenous immunoglobulin therapy markedly ameliorates muscle weakness and severe pain in proximal diabetic neuropathy. J Neurol Neurosurg Psychiatry. Aug 2007;78(8):899-901. [Medline].
Wada Y, Yanagihara C, Nishimura Y, et al. A case of diabetic amyotrophy with severe atrophy and weakness of shoulder girdle muscles showing good response to intravenous immune globulin. Diabetes Res Clin Pract. Jan 2007;75(1):107-10. [Medline].
Gulve EA. Exercise and glycemic control in diabetes: benefits, challenges, and adjustments to pharmacotherapy. Phys Ther. Sep 18 2008;[Medline].
Further Reading
Keywords
diabetic lumbosacral plexopathy, diabetes mellitus, diabetes mellitus type 1, diabetes mellitus type 2, type 1 diabetes, diabetes type 1, type 2 diabetes, diabetes 1, diabetes 2, diabetic neuropathy, neuropathy, lumbosacral, lumbar sacral, plexopathy, lumbosacral plexopathy, proximal neuropathy, amyotrophy, diabetic amyotrophy, distal symmetrical polyneuropathy, DSPN, polyneuropathy, Bruns-Garland syndrome, diabetic proximal neuropathy, diabetic lumbosacral polyradiculopathy, polyradiculopathy, diabetic lumbosacral radiculoplexus neuropathy(DLRPN), diabetic femoral neuropathy, ischemic mononeuropathymultiplex associated with diabetes mellitus, proximal lower limb motor neuropathy
Follow-up: Diabetic Lumbosacral Plexopathy