Neoplastic Brachial Plexopathy Follow-up
- Author: Mark A Wren, MD, MPH; Chief Editor: Robert H Meier III, MD more...
Further Inpatient Care
- Further inpatient care is needed if more invasive procedures are performed or if medical complications need to be monitored during radiation or chemotherapy.
Further Outpatient Care
- Routine follow-up care is necessary for monitoring the patient's condition and titrating medications.
Complications
- Potential complications of NBP include rapid progression of symptoms with disabling pain, edema, muscle contractures, or bony deformities. Most patients with secondary neoplasms succumb to metastatic involvement of vital organs within a few years.
Prognosis
- Most patients with benign primary neoplasms have a good prognosis, while patients with malignant primary neoplasms have a less favorable prognosis, regardless of therapy performed. For secondary neoplasms, most patients succumb to death within a few years from metastases to vital organs. On the other hand, preservation of some function and provision of adequate analgesia may be realistic goals for many patients.
Patient Education
- See the Rehabilitation Program section above.
Kim DH, Murovic JA, Tiel RL. A series of 397 peripheral neural sheath tumors: 30-year experience at Louisiana State University Health Sciences Center. J Neurosurg. Feb 2005;102(2):246-55.
Siqueira MG, Martins RS, Teixeira MJ. Management of brachial plexus region tumours and tumour-like conditions: relevant diagnostic and surgical features in a consecutive series of eighteen patients. Acta Neurochir (Wien). Sep 2009;151(9):1089-98. [Medline].
Kori SH, Foley KM, Posner JB. Brachial plexus lesions in patients with cancer: 100 cases. Neurology. Jan 1981;31(1):45-50. [Medline].
Killer HE, Hess K. Natural history of radiation-induced brachial plexopathy compared with surgically treated patients. J Neurol. Jul 1990;237(4):247-50.
Kamenova B, Braverman AS, Schwartz M, et al. Effective treatment of the brachial plexus syndrome in breast cancer patients by early detection and control of loco-regional metastases with radiation or systemic therapy. Int J Clin Oncol. Jun 2009;14(3):219-24. [Medline].
Gerevini S, Mandelli C, Cadioli M, Scotti G. Diagnostic value and surgical implications of the magnetic resonance imaging in the management of adult patients with brachial plexus pathologies. Surg Radiol Anat. Mar 2008;30(2):91-101. [Medline].
Cross NE, Glantz MJ. Neurologic complications of radiation therapy. Neurol Clin. Feb 2003;21(1):249-77. [Medline].
Dumitru D. Brachial plexopathy and proximal mononeuropathies. In: Electrodiagnostic Medicine. Philadelphia:. Hanley & Belfus Inc;1995:585-642.
Harper CM Jr, Thomas JE, Cascino TL, Litchy WJ. Distinction between neoplastic and radiation-induced brachial plexopathy, with emphasis on the role of EMG. Neurology. Apr 1989;39(4):502-6. [Medline].
Hathaway PB, Mankoff DA, Maravilla KR, et al. Value of combined FDG PET and MR imaging in the evaluation of suspected recurrent local-regional breast cancer: preliminary experience. Radiology. Mar 1999;210(3):807-14. [Medline].
Kline DG, Judice DJ. Operative management of selected brachial plexus lesions. J Neurosurg. May 1983;58(5):631-49.
Lachance DH, O''Neill BP, Harper CM Jr, et al. Paraneoplastic brachial plexopathy in a patient with Hodgkin''s disease. Mayo Clin Proc. Jan 1991;66(1):97-101.
Liang R, Kay R, Maisey MN. Brachial plexus infiltration by non-Hodgkin''s lymphoma. Br J Radiol. Nov 1985;58(695):1125-7. [Medline].
Meador KJ, Richards B, Hunter S, et al. Bibrachial palsy due to paraneoplastic encephalomyelitis. South Med J. Aug 1989;82(8):1053-5. [Medline].
Mukherji SK, Castillo M, Wagle AG. The brachial plexus. Seminars in Ultrasound, CT and MRI. Semin Ultrasound CT MR. Dec 1996;17(6):519-38. [Medline].
Pierce SM, Recht A, Lingos TI, et al. Long-term radiation complications following conservative surgery (CS) and radiation therapy (RT) in patients with early stage breast cancer. Int J Radiat Oncol Biol Phys. 1992;23(5):915-23. [Medline].
Stewart JB. The brachial plexus. In: Focal Peripheral Neuropathies. New York, NY:. Raven Press Ltd;1993:111-140.
Weber RJ. Rehabilitation issues in plexopathies. In: Physical Medicine and Rehabilitation. Philadelphia: WB Saunders Co:. 990-1001.
Wilbourn AJ. Brachial plexus disorders. In: Peripheral Neuropathy, PDPTJE. Philadelphia:. WB Saunders Co;1993:911-50.
Wilbourn AJ. Electrodiagnosis of plexopathies. Neurol Clin. Aug 1985;3(3):511-29. [Medline].

