eMedicine Specialties > Physical Medicine and Rehabilitation > Plexopathy

Radiation-Induced Brachial Plexopathy: Follow-up

Author: Robert J Kaplan, MD, James E Van Zandt VA Medical Center, Staff Physician, Department of Rehabilitation Medicine
Contributor Information and Disclosures

Updated: Jun 11, 2009

Follow-up

Further Outpatient Care

  • Continue to monitor the neurologic examination findings. If changes occur, consider repeating electromyelography or MRI.
  • Reinforce patient education regarding protection and care of the extremity with lymphedema. If lymphedema worsens, consider the aforementioned therapeutic interventions and perform an MRI to rule out metastatic disease.

Inpatient & Outpatient Medications

  • For pain control - Tricyclic antidepressants or anticonvulsants for lancinating pain

Transfer

  • If there is evidence of neoplastic disease, the patient needs to be enrolled in an appropriate facility for radiation or chemotherapy.

Deterrence

  • Use radiotherapy doses below 60 cGy.

Complications

  • Lymphangitis
  • Cellulitis
  • Complex regional pain syndrome, type 2
  • Glenohumeral joint subluxation
  • Contractures in the involved upper extremity

Prognosis

  • One third of patients experience significant progression of their radiation-induced plexopathy, whereas the remainder of patients demonstrate gradual progression.

Patient Education

  • Educate patients about lowering the risks of infection secondary to the incident associated with upper extremity trauma.

Miscellaneous

Medicolegal Pitfalls

  • Failure to make an accurate diagnosis of radiation-induced brachial plexopathy
 


More on Radiation-Induced Brachial Plexopathy

Overview: Radiation-Induced Brachial Plexopathy
Differential Diagnoses & Workup: Radiation-Induced Brachial Plexopathy
Treatment & Medication: Radiation-Induced Brachial Plexopathy
Follow-up: Radiation-Induced Brachial Plexopathy
References
Further Reading

References

  1. Wong M, Tang AL, Umapathi T. Partial ulnar nerve transfer to the nerve to the biceps for the treatment of brachial plexopathy in metastatic breast carcinoma: case report. J Hand Surg Am. Jan 2009;34(1):79-82. [Medline].

  2. Galecki J, Hicer-Grzenkowicz J, Grudzien-Kowalska M, et al. Radiation-induced brachial plexopathy and hypofractionated regimens in adjuvant irradiation of patients with breast cancer--a review. Acta Oncol. 2006;45(3):280-4. [Medline][Full Text].

  3. Schierle C, Winograd JM. Radiation-induced brachial plexopathy: review. Complication without a cure. J Reconstr Microsurg. Feb 2004;20(2):149-52. [Medline].

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  5. Forquer JA, Fakiris AJ, Timmerman RD, et al. Brachial plexopathy from stereotactic body radiotherapy in early-stage NSCLC: Dose-limiting toxicity in apical tumor sites. Radiother Oncol. May 17 2009;[Medline].

  6. Sureka J, Cherian RA, Alexander M, et al. MRI of brachial plexopathies. Clin Radiol. Feb 2009;64(2):208-18. [Medline].

  7. Tung TH, Liu DZ, Mackinnon SE. Nerve transfer for elbow flexion in radiation-induced brachial plexopathy: a case report. Hand (N Y). Jun 2009;4(2):123-8. [Medline].

  8. Delanian S, Balla-Mekias S, Lefaix JL. Striking regression of chronic radiotherapy damage in a clinical trial of combined pentoxifylline and tocopherol. J Clin Oncol. Oct 1999;17(10):3283-90. [Medline].

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Keywords

radiation-induced brachial plexopathy, brachial plexusplexopathy, brachial plexopathyradiation therapy, radiation treatment, breast cancer radiation therapy, breast radiation therapy, cancer radiation therapy, irradiation brachial plexopathy,

Contributor Information and Disclosures

Author

Robert J Kaplan, MD, James E Van Zandt VA Medical Center, Staff Physician, Department of Rehabilitation Medicine
Robert J Kaplan, MD is a member of the following medical societies: American Academy of Physical Medicine and Rehabilitation, Association of Academic Physiatrists, and Physiatric Association of Spine, Sports and Occupational Rehabilitation
Disclosure: Nothing to disclose.

Medical Editor

Rajesh R Yadav, MD, Assistant Professor, Section of Physical Medicine and Rehabilitation, MD Anderson Cancer Center, University of Texas at Houston
Rajesh R Yadav, MD is a member of the following medical societies: American Academy of Physical Medicine and Rehabilitation
Disclosure: Nothing to disclose.

Pharmacy Editor

Francisco Talavera, PharmD, PhD, Senior Pharmacy Editor, eMedicine
Disclosure: eMedicine Salary Employment

Managing Editor

Patrick M Foye, MD, FAAPMR, FAAEM, Associate Professor of Physical Medicine and Rehabilitation, Co-Director of Musculoskeletal Fellowship, Co-Director of Back Pain Clinic, Director of Coccyx Pain Service (Tailbone Pain Service: www.TailboneDoctor.com), University of Medicine and Dentistry of New Jersey, New Jersey Medical School
Patrick M Foye, MD, FAAPMR, FAAEM is a member of the following medical societies: American Academy of Physical Medicine and Rehabilitation, American Association of Neuromuscular and Electrodiagnostic Medicine, Association of Academic Physiatrists, and International Spine Intervention Society
Disclosure: Nothing to disclose.

CME Editor

Kelly L Allen, MD, Regional Medical Director, IMX-Medical Management Services
Disclosure: Nothing to disclose.

Chief Editor

Robert H Meier III, MD, Director, Amputee Services of America; Active Medical Staff, Presbyterian/St Luke's Hospital, Spalding Rehabilitation Hospital, Select Specialty Hospital; Consulting Staff, Kindred Hospital
Robert H Meier III, MD is a member of the following medical societies: American Academy of Physical Medicine and Rehabilitation and Association of Academic Physiatrists
Disclosure: Nothing to disclose.

 
 
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