eMedicine Specialties > Physical Medicine and Rehabilitation > Plexopathy
Radiation-Induced Brachial Plexopathy: Follow-up
Updated: Jun 11, 2009
Follow-up
Further Outpatient Care
- Continue to monitor the neurologic examination findings. If changes occur, consider repeating electromyelography or MRI.
- Reinforce patient education regarding protection and care of the extremity with lymphedema. If lymphedema worsens, consider the aforementioned therapeutic interventions and perform an MRI to rule out metastatic disease.
Inpatient & Outpatient Medications
- For pain control - Tricyclic antidepressants or anticonvulsants for lancinating pain
Transfer
- If there is evidence of neoplastic disease, the patient needs to be enrolled in an appropriate facility for radiation or chemotherapy.
Deterrence
- Use radiotherapy doses below 60 cGy.
Complications
- Lymphangitis
- Cellulitis
- Complex regional pain syndrome, type 2
- Glenohumeral joint subluxation
- Contractures in the involved upper extremity
Prognosis
- One third of patients experience significant progression of their radiation-induced plexopathy, whereas the remainder of patients demonstrate gradual progression.
Patient Education
- Educate patients about lowering the risks of infection secondary to the incident associated with upper extremity trauma.
Miscellaneous
Medicolegal Pitfalls
- Failure to make an accurate diagnosis of radiation-induced brachial plexopathy
More on Radiation-Induced Brachial Plexopathy |
| Overview: Radiation-Induced Brachial Plexopathy |
| Differential Diagnoses & Workup: Radiation-Induced Brachial Plexopathy |
| Treatment & Medication: Radiation-Induced Brachial Plexopathy |
Follow-up: Radiation-Induced Brachial Plexopathy |
| References |
| Further Reading |
| « Previous Page |
References
Wong M, Tang AL, Umapathi T. Partial ulnar nerve transfer to the nerve to the biceps for the treatment of brachial plexopathy in metastatic breast carcinoma: case report. J Hand Surg Am. Jan 2009;34(1):79-82. [Medline].
Galecki J, Hicer-Grzenkowicz J, Grudzien-Kowalska M, et al. Radiation-induced brachial plexopathy and hypofractionated regimens in adjuvant irradiation of patients with breast cancer--a review. Acta Oncol. 2006;45(3):280-4. [Medline]. [Full Text].
Schierle C, Winograd JM. Radiation-induced brachial plexopathy: review. Complication without a cure. J Reconstr Microsurg. Feb 2004;20(2):149-52. [Medline].
Shimazaki H, Nakano I. [Radiation myelopathy and plexopathy]. Brain Nerve. Feb 2008;60(2):115-21. [Medline].
Forquer JA, Fakiris AJ, Timmerman RD, et al. Brachial plexopathy from stereotactic body radiotherapy in early-stage NSCLC: Dose-limiting toxicity in apical tumor sites. Radiother Oncol. May 17 2009;[Medline].
Sureka J, Cherian RA, Alexander M, et al. MRI of brachial plexopathies. Clin Radiol. Feb 2009;64(2):208-18. [Medline].
Tung TH, Liu DZ, Mackinnon SE. Nerve transfer for elbow flexion in radiation-induced brachial plexopathy: a case report. Hand (N Y). Jun 2009;4(2):123-8. [Medline].
Delanian S, Balla-Mekias S, Lefaix JL. Striking regression of chronic radiotherapy damage in a clinical trial of combined pentoxifylline and tocopherol. J Clin Oncol. Oct 1999;17(10):3283-90. [Medline].
Fathers E, Thrush D, Huson SM, Norman A. Radiation-induced brachial plexopathy in women treated for carcinoma of the breast. Clin Rehabil. Mar 2002;16(2):160-5. [Medline].
Garden FH. Radiation injury to the spinal cord and peripheral nerves. State of the art reviews PM&R. 1994;8:405-411.
Hoeller U, Rolofs K, Bajrovic A, et al. A patient questionnaire for radiation-induced brachial plexopathy. Am J Clin Oncol. Feb 2004;27(1):1-7. [Medline].
Jaeckle KA. Plexopathies in cancer patients. In: Levin, Victor A, ed. Cancer in the Nervous System. New York, NY: Churchill Livingstone; 1996:347-60.
Kori SH. Diagnosis and management of brachial plexus lesions in cancer patients. Oncology (Huntingt). Aug 1995;9(8):756-60; discussion 765. [Medline].
Mondrup K, Olsen NK, Pfeiffer P, Rose C. Clinical and electrodiagnostic findings in breast cancer patients with radiation-induced brachial plexus neuropathy. Acta Neurol Scand. Feb 1990;81(2):153-8. [Medline].
Pierce SM, Recht A, Lingos TI, et al. Long-term radiation complications following conservative surgery (CS) and radiation therapy (RT) in patients with early stage breast cancer. Int J Radiat Oncol Biol Phys. 1992;23(5):915-23. [Medline].
Posner JB. Side effects of radiation therapy. In: Neurologic Complications of Cancer. Philadelphia, Pa: FA Davis; 1995:311-37.
Stubgen JP. Neuromuscular disorders in systemic malignancy and its treatment. Muscle Nerve. Jun 1995;18(6):636-48. [Medline].
Further Reading
Related eMedicine topics:
Brachial Neuritis
Diabetic Lumbosacral Plexopathy
Neoplastic Brachial Plexopathy
Neoplastic Lumbosacral Plexopathy
Radiation-Induced Lumbosacral Plexopathy
Traumatic Brachial Plexopathy
Clinical guidelines:
ACR Appropriateness Criteria® plexopathy. American College of Radiology - Medical Specialty Society. 2006. 13 pages. NGC:005539
Clinical trials:
Stem Cell Therapy to Improve the Muscle Function of Patients With Partly Denervated Muscles of the Arm
Keywords
radiation-induced brachial plexopathy, brachial plexus, plexopathy, brachial plexopathy, radiation therapy, radiation treatment, breast cancer radiation therapy, breast radiation therapy, cancer radiation therapy, irradiation brachial plexopathy,
Follow-up: Radiation-Induced Brachial Plexopathy