eMedicine Specialties > Rheumatology > Systemic Rheumatic Disease

Sjogren Syndrome: Multimedia

Author: Anne V Miller, MD, Assistant Professor of Medicine, Division of Rheumatology, Southern Illinois University School of Medicine
Coauthor(s): Sriya K M Ranatunga, MD, MPH,, Assistant Professor, Department of Clinical Medicine, Southern Illinois University School of Medicine; Mark L Francis, MD, Chief, Associate Professor, Department of Internal Medicine, Division of Rheumatology, Southern Illinois University School of Medicine
Contributor Information and Disclosures

Updated: Mar 13, 2009

Multimedia

Sjögren syndrome. Marked bilateral parotid g...
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Media file 1: Sjögren syndrome. Marked bilateral parotid gland enlargement in a patient with primary Sjögren syndrome. Sicca syndrome is a common clinical finding.
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Sjögren syndrome. Marked bilateral parotid g...

Sjögren syndrome. Marked bilateral parotid gland enlargement in a patient with primary Sjögren syndrome. Sicca syndrome is a common clinical finding.

Sjögren syndrome. Clinical photograph and ph...
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Media file 2: Sjögren syndrome. Clinical photograph and photomicrograph of a 48-year-old man with Sjögren syndrome with a large left parotid mass. On biopsy, B-cell lymphoma of mucosa-associated lymphoid tissue (MALT) type was identified. Microscopic section of parotid biopsy, stained with immunoperoxidase for kappa light chains (brown-stained cells), showed monoclonal population of B cells, confirming the diagnosis.
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Sjögren syndrome. Clinical photograph and ph...

Sjögren syndrome. Clinical photograph and photomicrograph of a 48-year-old man with Sjögren syndrome with a large left parotid mass. On biopsy, B-cell lymphoma of mucosa-associated lymphoid tissue (MALT) type was identified. Microscopic section of parotid biopsy, stained with immunoperoxidase for kappa light chains (brown-stained cells), showed monoclonal population of B cells, confirming the diagnosis.

Sjögren syndrome. Photograph that demonstrat...
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Media file 3: Sjögren syndrome. Photograph that demonstrates the Schirmer test, which is used to detect deficient tear production in patients with Sjögren syndrome. The filter paper strip is placed at the junction of the eyelid margins. After 5 minutes, 15 mm of paper should be moistened if tear production is normal, as shown here. Persons older than 40 years may moisten between 10 mm and 15 mm. Patients with Sjögren syndrome have less moistening. Sjögren syndrome is most common in patients with rheumatoid arthritis but may also occur without associated disease and in systemic lupus erythematosus, polyarteritis, systemic sclerosis, lymphoma, and sarcoidosis.
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Sjögren syndrome. Photograph that demonstrat...

Sjögren syndrome. Photograph that demonstrates the Schirmer test, which is used to detect deficient tear production in patients with Sjögren syndrome. The filter paper strip is placed at the junction of the eyelid margins. After 5 minutes, 15 mm of paper should be moistened if tear production is normal, as shown here. Persons older than 40 years may moisten between 10 mm and 15 mm. Patients with Sjögren syndrome have less moistening. Sjögren syndrome is most common in patients with rheumatoid arthritis but may also occur without associated disease and in systemic lupus erythematosus, polyarteritis, systemic sclerosis, lymphoma, and sarcoidosis.

Sjögren syndrome. Dryness of the mouth and t...
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Media file 4: Sjögren syndrome. Dryness of the mouth and tongue due to lack of salivary secretion is characteristic of xerostomia associated with Sjögren syndrome. Mouth dryness may produce a deep red tongue, as shown here, and dental caries are common.
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Sjögren syndrome. Dryness of the mouth and t...

Sjögren syndrome. Dryness of the mouth and tongue due to lack of salivary secretion is characteristic of xerostomia associated with Sjögren syndrome. Mouth dryness may produce a deep red tongue, as shown here, and dental caries are common.

Sjögren syndrome. Photomicrograph of a lip b...
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Media file 5: Sjögren syndrome. Photomicrograph of a lip biopsy specimen showing two lymphocytic foci adjacent to normal-appearing mucinous acini typical of minor salivary gland abnormalities in Sjögren syndrome.
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Sjögren syndrome. Photomicrograph of a lip b...

Sjögren syndrome. Photomicrograph of a lip biopsy specimen showing two lymphocytic foci adjacent to normal-appearing mucinous acini typical of minor salivary gland abnormalities in Sjögren syndrome.

More on Sjogren Syndrome

Overview: Sjogren Syndrome
Differential Diagnoses & Workup: Sjogren Syndrome
Treatment & Medication: Sjogren Syndrome
Follow-up: Sjogren Syndrome
Multimedia: Sjogren Syndrome
References
Further Reading
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References

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Further Reading

Additional resources on Sjögren syndrome are available at Medscape's Sjögren's Syndrome Resource Center.

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Keywords

Sjogren's syndrome, Sjögren’s syndrome, Sjogren syndrome, Sjögren syndrome, SS, primary Sjögren syndrome, secondary Sjögren syndrome, Mikulicz disease, Gougerot syndrome, Gougerot's syndrome, autoimmune exocrinopathy, epithelitis, sicca complex, xerophthalmia, dry eye disease, dry eye syndrome, parotid gland enlargement, connective tissue disease, systemic lupus erythematosus, SLE, rheumatoid arthritis, RA, scleroderma, sicca symptoms, parotitis, polymyositis, primary biliary cirrhosis, thyroiditis, chronic active hepatitis, mixed cryoglobulinemia, MALT lymphoma, Shogren syndrome, Schogren syndrome

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Contributor Information and Disclosures

Author

Anne V Miller, MD, Assistant Professor of Medicine, Division of Rheumatology, Southern Illinois University School of Medicine
Anne V Miller, MD is a member of the following medical societies: Alpha Omega Alpha, American College of Physicians, American College of Rheumatology, and International Society for Clinical Densitometry
Disclosure: Nothing to disclose.

Coauthor(s)

Sriya K M Ranatunga, MD, MPH,, Assistant Professor, Department of Clinical Medicine, Southern Illinois University School of Medicine
Disclosure: Nothing to disclose.

Mark L Francis, MD, Chief, Associate Professor, Department of Internal Medicine, Division of Rheumatology, Southern Illinois University School of Medicine
Mark L Francis, MD is a member of the following medical societies: American Association of Immunologists, American College of Physicians, American College of Rheumatology, American Medical Association, Illinois State Medical Society, and Phi Beta Kappa
Disclosure: Nothing to disclose.

Medical Editor

Carlos J Lozada, MD, Director of Rheumatology Fellowship Program, Associate Professor, Department of Medicine, Division of Rheumatology and Immunology, Jackson Memorial Medical Center, University of Miami School of Medicine
Carlos J Lozada, MD is a member of the following medical societies: American College of Physicians and American College of Rheumatology
Disclosure: Nothing to disclose.

Pharmacy Editor

Francisco Talavera, PharmD, PhD, Senior Pharmacy Editor, eMedicine
Disclosure: eMedicine Salary Employment

Managing Editor

Elliot Goldberg, MD, Dean of the Western Pennsylvania Clinical Campus, Professor, Department of Medicine, Temple University School of Medicine
Elliot Goldberg, MD is a member of the following medical societies: Alpha Omega Alpha, American College of Physicians, and American College of Rheumatology
Disclosure: Nothing to disclose.

CME Editor

Alex J Mechaber, MD, FACP, Associate Dean for Undergraduate Medical Education, Associate Professor of Medicine, University of Miami Miller School of Medicine
Alex J Mechaber, MD, FACP is a member of the following medical societies: Alpha Omega Alpha, American College of Physicians-American Society of Internal Medicine, and Society of General Internal Medicine
Disclosure: Nothing to disclose.

Chief Editor

Herbert S Diamond, MD, Professor of Medicine, Temple University School of Medicine; Chairman Emeritus, Department of Internal Medicine, Western Pennsylvania Hospital
Herbert S Diamond, MD is a member of the following medical societies: Alpha Omega Alpha, American College of Physicians, American College of Rheumatology, American Medical Association, and Phi Beta Kappa
Disclosure: medifocus Honoraria Review panel membership; health dialogs Honoraria Consulting; West Penn Allegheny Health System None Board membership

 
 
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