AA (Inflammatory) Amyloidosis Differential Diagnoses
- Author: Richa Dhawan, MD; Chief Editor: Herbert S Diamond, MD more...
Differential Diagnoses
- Amyloidosis, Familial Renal
- Amyloidosis, Immunoglobulin-Related
- Glomerulonephritis, Membranous
- Renal Vein Thrombosis
Perfetto F, Moggi-Pignone A, Livi R, Tempestini A, Bergesio F, Matucci-Cerinic M. Systemic amyloidosis: a challenge for the rheumatologist. Nat Rev Rheumatol. Jul 2010;6(7):417-29. [Medline].
Obici L, Raimondi S, Lavatelli F, Bellotti V, Merlini G. Susceptibility to AA amyloidosis in rheumatic diseases: a critical overview. Arthritis Rheum. Oct 15 2009;61(10):1435-40. [Medline].
Sipe J. Revised nomenclature for serum amyloid A (SAA). Nomenclature Committee of the International Society of Amyloidosis. Part 2. Amyloid. Mar 1999;6(1):67-70. [Medline].
Simms RW, Prout MN, Cohen AS. The epidemiology of AL and AA amyloidosis. Baillieres Clin Rheumatol. Aug 1994;8(3):627-34. [Medline].
Lachmann HJ, Goodman HJ, Gilbertson JA, Gallimore JR, Sabin CA, Gillmore JD, et al. Natural history and outcome in systemic AA amyloidosis. N Engl J Med. Jun 7 2007;356(23):2361-71. [Medline].
Myllykangas-Luosujärvi R, Aho K, Kautiainen H, Hakala M. Amyloidosis in a nationwide series of 1666 subjects with rheumatoid arthritis who died during 1989 in Finland. Rheumatology (Oxford). Jun 1999;38(6):499-503. [Medline].
Gillmore JD, Lovat LB, Persey MR, Pepys MB, Hawkins PN. Amyloid load and clinical outcome in AA amyloidosis in relation to circulating concentration of serum amyloid A protein. Lancet. Jul 7 2001;358(9275):24-9. [Medline].
Immonen K, Finne P, Hakala M, Kautiainen H, Pettersson T, Grönhagen-Riska C. No improvement in survival of patients with amyloidosis associated with inflammatory rheumatic diseases -- data from the Finnish national registry for kidney diseases. J Rheumatol. Jul 2008;35(7):1334-8. [Medline].
Tanaka F, Migita K, Honda S, Fukuda T, Mine M, Nakamura T, et al. Clinical outcome and survival of secondary (AA) amyloidosis. Clin Exp Rheumatol. May-Jun 2003;21(3):343-6. [Medline].
Uda H, Yokota A, Kobayashi K, Miyake T, Fushimi H, Maeda A, et al. Two distinct clinical courses of renal involvement in rheumatoid patients with AA amyloidosis. J Rheumatol. Aug 2006;33(8):1482-7. [Medline].
Kofman T, Grimbert P, Poitrine FC, Zuber J, Garrigue V, Mousson C, et al. Renal Transplantation in Patients With AA Amyloidosis Nephropathy: Results From a French Multicenter Study. Am J Transplant. Jun 30 2011;[Medline].
Falk RH. Diagnosis and management of the cardiac amyloidoses. Circulation. Sep 27 2005;112(13):2047-60. [Medline].
Silva L, Sampaio L, Terroso G, Almeida G, Lucas R, Rios E, et al. Amyloidosis secondary to rheumatic diseases - 16 cases. Acta Reumatol Port. Oct-Dec 2010;35(5):518-23. [Medline].
Wester AL, Vatn MH, Fausa O. Secondary amyloidosis in inflammatory bowel disease: a study of 18 patients admitted to Rikshospitalet University Hospital, Oslo, from 1962 to 1998. Inflamm Bowel Dis. Nov 2001;7(4):295-300. [Medline].
Lachmann HJ, Gilbertson JA, Gillmore JD, et al. Unicentric Castleman's disease complicated by systemic AA amyloidosis: a curable disease. QJM. Apr 2002;95(4):211-8. [Medline].
Picken MM. Amyloidosis-where are we now and where are we heading?. Arch Pathol Lab Med. Apr 2010;134(4):545-51. [Medline].
Ahlmen M, Ahlmen J, Svalander C, et al. Cytotoxic drug treatment of reactive amyloidosis in rheumatoid arthritis with special reference to renal insufficiency. Clin Rheumatol. Mar 1987;6(1):27-38. [Medline].
Fernández-Nebro A, Tomero E, Ortiz-Santamaría V, Castro MC, Olivé A, de Haro M, et al. Treatment of rheumatic inflammatory disease in 25 patients with secondary amyloidosis using tumor necrosis factor alpha antagonists. Am J Med. May 2005;118(5):552-6. [Medline].
Kuroda T, Otaki Y, Sato H, Fujimura T, Nakatsue T, Murakami S, et al. A case of AA amyloidosis associated with rheumatoid arthritis effectively treated with Infliximab. Rheumatol Int. Sep 2008;28(11):1155-9. [Medline].
Shimoyama M, Ohtahara A, Fukui H, Okamura T, Shimizu H, Miyamoto M, et al. Acute secondary gastrointestinal amyloidosis in a patient with rheumatoid arthritis. Am J Med Sci. Sep 2003;326(3):145-7. [Medline].
Leslie KS, Lachmann HJ, Bruning E, McGrath JA, Bybee A, Gallimore JR, et al. Phenotype, genotype, and sustained response to anakinra in 22 patients with autoinflammatory disease associated with CIAS-1/NALP3 mutations. Arch Dermatol. Dec 2006;142(12):1591-7. [Medline].
Fushimi T, Takahashi Y, Kashima Y, et al. Severe protein losing enteropathy with intractable diarrhea due to systemic AA amyloidosis, successfully treated with corticosteroid and octreotide. Amyloid. Mar 2005;12(1):48-53. [Medline].
Perez Equiza E, Arguinano JM, Gastearena J. Successful treatment of AA amyloidosis secondary to Hodgkin's disease with 4'-iodo-4'-deoxydoxorubicin. Haematologica. Jan 1999;84(1):93-4. [Medline].
Bodin K, Ellmerich S, Kahan MC, Tennent GA, Loesch A, Gilbertson JA, et al. Antibodies to human serum amyloid P component eliminate visceral amyloid deposits. Nature. Nov 4 2010;468(7320):93-7. [Medline]. [Full Text].
Dember LM, Hawkins PN, Hazenberg BP, Gorevic PD, Merlini G, Butrimiene I, et al. Eprodisate for the treatment of renal disease in AA amyloidosis. N Engl J Med. Jun 7 2007;356(23):2349-60. [Medline].
Ueda M, Ando Y, Nakamura M, Yamashita T, Himeno S, Kim J, et al. FK506 inhibits murine AA amyloidosis: possible involvement of T cells in amyloidogenesis. J Rheumatol. Nov 2006;33(11):2260-70. [Medline].
Yan SD, Zhu H, Zhu A, Golabek A, Du H, Roher A, et al. Receptor-dependent cell stress and amyloid accumulation in systemic amyloidosis. Nat Med. Jun 2000;6(6):643-51. [Medline].
Vandecasteele SJ, De Paepe P, De Vriese AS. Successful treatment of renal AA amyloidosis in familial Mediterranean fever with pegylated alpha-2a interferon. Clin Nephrol. Feb 2011;75 Suppl 1:1-3. [Medline].
Joss N, McLaughlin K, Simpson K, et al. Presentation, survival and prognostic markers in AA amyloidosis. QJM. Aug 2000;93(8):535-42. [Medline].
Akar N, Yalcinkaya F, Akar E, et al. MEFV mutation analysis in Turkish familial Mediterranean fever patients with amyloidosis. Amyloid. Dec 1999;6(4):301-2. [Medline].
Berglund K, Thysell H, Keller C. Results, principles and pitfalls in the management of renal AA-amyloidosis; a 10-21 year followup of 16 patients with rheumatic disease treated with alkylating cytostatics. J Rheumatol. Dec 1993;20(12):2051-7. [Medline].
Bohle A, Wehrmann M, Eissele R, et al. The long-term prognosis of AA and AL renal amyloidosis and the pathogenesis of chronic renal failure in renal amyloidosis. Pathol Res Pract. Apr 1993;189(3):316-31. [Medline].
Booth DR, Booth SE, Gillmore JD, et al. SAA1 alleles as risk factors in reactive systemic AA amyloidosis. Amyloid. Dec 1998;5(4):262-5. [Medline].
Buck FS, Koss MN, Sherrod AE, et al. Ethnic distribution of amyloidosis: an autopsy study. Mod Pathol. Jul 1989;2(4):372-7. [Medline].
Buxbaum J. The amyloidoses. In: Dieppe PA, Klippel JH, eds. Rheumatology. 2nd ed. St. Louis, Mo: Mosby; 1998:1-10.
Cunnane G, Whitehead AS. Amyloid precursors and amyloidosis in rheumatoid arthritis. Baillieres Best Pract Res Clin Rheumatol. Dec 1999;13(4):615-28. [Medline].
Drewe E, Huggins ML, Morgan AG, et al. Treatment of renal amyloidosis with etanercept in tumour necrosis factor receptor-associated periodic syndrome. Rheumatology (Oxford). Nov 2004;43(11):1405-8. [Medline].
Gabay C, Kushner I. Acute-phase proteins and other systemic responses to inflammation. N Engl J Med. Feb 11 1999;340(6):448-54. [Medline].
Gallo GR, Feiner HD, Chuba JV, et al. Characterization of tissue amyloid by immunofluorescence microscopy. Clin Immunol Immunopathol. Jun 1986;39(3):479-90. [Medline].
Gertz MA, Kyle RA. Secondary systemic amyloidosis: response and survival in 64 patients. Medicine (Baltimore). Jul 1991;70(4):246-56. [Medline].
Heering P, Hetzel R, Grabensee B, et al. Renal transplantation in secondary systemic amyloidosis. Clin Transplant. Jun 1998;12(3):159-64. [Medline].
Helin HJ, Korpela MM, Mustonen JT, et al. Renal biopsy findings and clinicopathologic correlations in rheumatoid arthritis. Arthritis Rheum. Feb 1995;38(2):242-7. [Medline].
Hirschfield GM. Amyloidosis: a clinico-pathophysiological synopsis. Semin Cell Dev Biol. Feb 2004;15(1):39-44. [Medline].
Janssen S, Van Rijswijk MH, Meijer S, et al. Systemic amyloidosis: a clinical survey of 144 cases. Neth J Med. 1986;29(11):376-85. [Medline].
Joss N, McLaughlin K, Simpson K, Boulton-Jones JM. Presentation, survival and prognostic markers in AA amyloidosis. QJM. Aug 2000;93(8):535-42. [Medline].
Kisilevsky R, Young ID. Pathogenesis of amyloidosis. Baillieres Clin Rheumatol. Aug 1994;8(3):613-26. [Medline].
Lachmann HJ, Gilbertson JA, Gillmore JD, Hawkins PN, Pepys MB. Unicentric Castleman's disease complicated by systemic AA amyloidosis: a curable disease. QJM. Apr 2002;95(4):211-8. [Medline].
Lachmann HJ, Goodman HJ, Gilbertson JA, Gallimore JR, Sabin CA, Gillmore JD, et al. Natural history and outcome in systemic AA amyloidosis. N Engl J Med. Jun 7 2007;356(23):2361-71. [Medline].
Lam SKL, Ngian GS, Travers R, Lim KKT. Amyloidosis: a rheumatological perspective on diagnosis, further investigation and treatment. International Journal of Rheumatic Diseases. Jun 2008;11(1):55-9.
Lee H, Han KH, Jung YH, Kang HG, Moon KC, Ha IS, et al. A case of systemic amyloidosis associated with cyclic neutropenia. Pediatr Nephrol. Apr 2011;26(4):625-9. [Medline].
Livneh A, Langevitz P, Shinar Y, et al. MEFV mutation analysis in patients suffering from amyloidosis of familial Mediterranean fever. Amyloid. Mar 1999;6(1):1-6. [Medline].
Livneh A, Zemer D, Langevitz P, et al. Colchicine treatment of AA amyloidosis of familial Mediterranean fever. An analysis of factors affecting outcome. Arthritis Rheum. Dec 1994;37(12):1804-11. [Medline].
Lofberg H, Thysell H, Westman K, et al. Demonstration and classification of amyloidosis in needle biopsies of the kidneys, with special reference to amyloidosis of the AA-type. Acta Pathol Microbiol Immunol Scand [A]. Nov 1987;95(6):357-63. [Medline].
Mihara M, Shiina M, Nishimoto N, et al. Anti-interleukin 6 receptor antibody inhibits murine AA-amyloidosis. J Rheumatol. Jun 2004;31(6):1132-8. [Medline].
Moriguchi M, Terai C, Koseki Y, et al. Influence of genotypes at SAA1 and SAA2 loci on the development and the length of latent period of secondary AA-amyloidosis in patients with rheumatoid arthritis. Hum Genet. Oct 1999;105(4):360-6. [Medline].
Nakamura T. Clinical strategies for amyloid A amyloidosis secondary to rheumatoid arthritis. Mod Rheumatol. 2008;18(2):109-18. [Medline].
Naya MT, Soria C, Quereda C, Orte L, Romero R, Ortuño J. End-stage renal disease in a patient with amyloidosis secondary to acne conglobata. Nephron. 1991;57(1):109-10. [Medline].
Obici L, Perfetti V, Palladini G, et al. Clinical aspects of systemic amyloid diseases. Biochim Biophys Acta. Nov 10 2005;1753(1):11-22. [Medline].
Oka T, Iwata J, Furihata M, Sonobe H, Miyoshi I, Ohtsuki Y. Inhibitory effects of human interferons on the immortalization of human, but not rabbit, T lymphocytes by human T-lymphotropic virus type-I (HTLV-I). Int J Cancer. Jul 30 1992;51(6):915-20. [Medline].
Oka T, Iwata J, Furihata M, Sonobe H, Miyoshi I, Ohtsuki Y. Inhibitory effects of human interferons on the immortalization of human, but not rabbit, T lymphocytes by human T-lymphotropic virus type-I (HTLV-I). Int J Cancer. Jul 30 1992;51(6):915-20. [Medline].
Sipe J. Revised nomenclature for serum amyloid A (SAA). Nomenclature Committee of the International Society of Amyloidosis. Part 2. Amyloid. Mar 1999;6(1):67-70. [Medline].
van der Hilst JC, Yamada T, Op den Camp HJ, van der Meer JW, Drenth JP, Simon A. Increased susceptibility of serum amyloid A 1.1 to degradation by MMP-1: potential explanation for higher risk of type AA amyloidosis. Rheumatology (Oxford). Nov 2008;47(11):1651-4. [Medline].
Wiland P, Wojtala R, Goodacre J, Szechinski J. The prevalence of subclinical amyloidosis in Polish patients with rheumatoid arthritis. Clin Rheumatol. Jun 2004;23(3):193-8. [Medline].
Zhang CL, Lyngmo V, Nordøy A. The effects of saturated fatty acids on endothelial cells. Thromb Res. Jan 1 1992;65(1):65-75. [Medline].

